Clinical trials
Probiotic clinical trials
Below are recruiting probiotic clinical trials, each written for real people, not researchers. We’re tracking 223 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06092554Recruiting
Probiotics to prevent pneumonia in ventilated patients
This trial tests whether giving probiotics to patients on a breathing machine (mechanical ventilation) can help prevent pneumonia. It is for adults who are on a ventilator after a recent head injury, stroke, or brain bleed.
BrusselsAges 18–80 - NCT06158152Recruiting
AM3 supplement for metabolic syndrome pilot study
This study tests an oral supplement called AM3 in people with metabolic syndrome. It looks at whether the supplement can help improve sugar and fat levels in the blood.
MadridAges 18–75 - NCT06186089Recruiting
How stomach surgery affects gut bacteria and your thinking
This study looks at how having stomach cancer surgery changes your gut bacteria and thinking abilities. Researchers want to understand if these changes affect memory or brain function after the operation.
Wuhan, HubeiAges 40–80 - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT06268964RecruitingPhase 1/Phase 2
Trimebutine vs probiotics for kids with belly pain
This study compares two treatments—trimebutine and probiotics—to see which works better for children with recurring stomach pain that has no clear medical cause. It aims to find a safe and effective option for kids aged 4 to 18.
ColimaAges 4–18 - NCT06284577Recruiting
Quality of life and gut health in children with cystic fibrosis
This study looks at how a drug called ETI (a combination of three medicines) affects the quality of life and gut health of children with cystic fibrosis. If you or your child has the right type of CF and is between 2 and 18 years old, this trial may help us understand how treatment improves daily life and digestion.
OsloAges 2–18 - NCT06309199Recruiting
Healthy Baby Digestive Health and Probiotics Study
This study looks at how common digestive problems are in healthy babies and whether probiotics can help. It involves following your baby from birth to age 1 with regular check-ups.
Bangkok, BangkokAges 3 days–1 year - NCT07694791Recruiting
Gut health supplements for people on peritoneal dialysis
This trial tests whether taking probiotic and prebiotic supplements can improve gut health in people receiving peritoneal dialysis at home. It may help with digestion and overall well-being.
Monterrey, Nuevo LeónAges 18 years+ - NCT06428422Recruiting
Probiotic supplement for advanced lung cancer
This trial tests if taking a probiotic supplement along with your standard lung cancer treatment can help you live longer and respond better to therapy. It is for people with advanced non-small cell lung cancer who have not tried immunotherapy before.
KonyaAges 19–90 - NCT06456229Recruiting
Probiotics after colorectal cancer surgery
This trial tests if taking probiotics (healthy bacteria) before and after surgery can help your bowels start working again sooner. It's for people having planned colorectal cancer surgery.
SingaporeAges 21–99 - NCT06505330Recruiting
Probiotics for kids with cleft palate
This study looks at whether giving probiotics (helpful bacteria) to children with cleft palate can improve the bacteria in their airways and possibly prevent infections. Researchers want to see if this simple treatment helps keep kids healthier.
Edegem, AntwerpAges 6 months–2 years - NCT06573892Recruiting
Gut Bacteria and Chronic Heart Failure
This study looks at how the bacteria in your gut (the microbiome) relates to chronic heart failure. Researchers want to see if certain probiotics (friendly bacteria) might help people with heart failure feel better.
AstanaAges 18 years+ - NCT06609447RecruitingPhase 4
Probiotic with vedolizumab for moderate ulcerative colitis
This study tests whether adding a special probiotic (VSL#3) to vedolizumab helps people with moderate ulcerative colitis more than vedolizumab alone. You may qualify if you are already planning to start vedolizumab and haven't responded well enough to other treatments.
Beijing, Beijing MunicipalityAges 18–85 - NCT06636240Recruiting
Mulberry for eczema in children
This study tests whether mulberry extract could help improve eczema symptoms in children. It is a small, early trial to see if this natural prebiotic is safe and helpful.
New Taipei City, TaiwanAges 6–17 - NCT06639425Recruiting
Testing a probiotic for newly diagnosed type 2 diabetes
This study tests whether a probiotic called Lactobacillus Paracasei LC19 can help control blood sugar in people who have just been diagnosed with type 2 diabetes and are not on any diabetes medications. It may be a natural way to manage the condition.
Beijing, Beijing MunicipalityAges 18–65 - NCT06700044Recruiting
Probiotics for high-risk pregnancy
This study tests whether taking a probiotic supplement during pregnancy can help prevent complications in women at risk for preeclampsia. You would take a daily probiotic or placebo pill from about 20 weeks until delivery.
LundAges 18 years+ - NCT06725888Recruiting
Vagitab-T for bacterial vaginosis
This study tests a medical device called Vagitab-T as an extra treatment for women with bacterial vaginosis who are already taking the antibiotic metronidazole. It may help prevent the infection from coming back.
Timișoara, Timiș CountyAges 18–65 - NCT06729671Recruiting
Probiotics for antipsychotic-related metabolic issues
This trial tests if a probiotic supplement can help reduce metabolic side effects (like weight gain or high blood sugar) caused by antipsychotic medications. It is for people with psychosis who are on stable treatment.
CorkAges 18–65 - NCT06755307Recruiting
Probiotic cream for diaper rash in babies
This study tests whether a probiotic (beneficial bacteria) cream can help heal diaper rash in babies. It's for otherwise healthy infants under 2 who have diaper dermatitis.
MariborAges 1 month–2 years - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06789484Recruiting
Study of gut bacteria in healthy newborns
This study looks at the gut bacteria of healthy, full-term newborns whose parents plan to breastfeed exclusively. It aims to understand how the gut microbiome develops in early life.
HvidovreAges Up to 1 day - NCT06898788RecruitingEarly Phase 1
Probiotics for depression in teens and young adults
This study tests whether a probiotic supplement can help improve depression in young people who are already taking an SSRI antidepressant. If you join, you will take a probiotic or placebo for several weeks and have your mood and brain activity checked.
San Francisco, CaliforniaAges 15–24 - NCT06959043Recruiting
Diet and exercise for type 2 diabetes
This study tests if a plant-based diet and exercise program can improve blood sugar control in people with type 2 diabetes. Participants will live in a hospital for 4 weeks to follow the program closely.
São Paulo, São PauloAges 45–70 - NCT07044310RecruitingPhase 2
Probiotics for preventing bone loss during breast cancer hormone therapy
This trial tests if a probiotic supplement can help prevent bone loss in women with HR-positive breast cancer who are starting an aromatase inhibitor. You would take the probiotic daily and provide blood and stool samples to see how it affects your bone health.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for probiotic?
- Yes. Clin2 currently lists 223 recruiting probiotic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a probiotic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a probiotic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.