Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 716 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06537934Recruiting
Advanced CT scan to check heart and lung health in lung disease
This study uses a special high-resolution CT scan to look at heart and lung problems in people with a type of lung disease that gets worse over time. It may help doctors understand how the heart is affected and guide better care.
MilanAges 18 years+ - NCT06532851Recruiting
Exercise therapy for knee cartilage health
This study tests whether specific exercises can improve your knee cartilage health and daily function. It is for people with a meniscus tear who are at risk for knee arthritis but don't have arthritis yet.
Ar RamthaAges 35–55 - NCT05676580Recruiting
Study of risk factors and vision changes in keratoconus
This study looks at what leads to keratoconus and how it progresses over time. It may help doctors better predict worsening vision and plan earlier care.
Montpellier, OccitanieAges 10–40 - NCT06127303RecruitingPhase 2
Toripalimab plus cryoablation for lung cancer with limited progression
This trial tests a combination of an immunotherapy drug (toripalimab) and a freezing treatment (cryoablation) for people with advanced non-small cell lung cancer that has started to grow again in only a few spots after initial treatment. It aims to see if this approach can help control the cancer without switching to a completely new therapy.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06262321RecruitingPhase 2
Chest Radiation for Advanced Lung Cancer at High Risk of Symptoms
This study tests whether giving radiation to tumors in the chest soon after starting systemic therapy can help prevent symptoms like pain, trouble breathing, or bleeding. It is for people with advanced non-small cell lung cancer that does not have certain gene changes and has high-risk tumors in the chest.
Rochester, New YorkAges 18 years+ - NCT06482905RecruitingPhase 1
CAR-T cell therapy for recurrent grade 4 brain tumors
This trial tests a new treatment called TX103 CAR-T cells for people with a grade 4 glioma (like glioblastoma) that has come back or gotten worse after standard treatment. The therapy uses your own immune cells that are specially trained to attack a marker called B7-H3 found on tumor cells.
Phoenix, ArizonaAges 18–75 - NCT06485076Recruiting
Early comfort care for multiple myeloma and aggressive lymphoma
This study offers a palliative care team (doctors and nurses focused on comfort and quality of life) to people newly diagnosed with multiple myeloma or with an aggressive lymphoma that has come back. The goal is to help manage symptoms early, so you feel better and stay stronger during your cancer treatment.
Toronto, OntarioAges 18 years+ - NCT04520048Recruiting
Blood vessel tests to predict preeclampsia worsening in pregnancy
This study measures blood vessel–related markers in pregnant people who already have high blood pressure or early preeclampsia. The goal is to predict who is more likely to get worse, so care can be better targeted.
Bobigny, Seine Saint DenisAges 18–40 - NCT06444412RecruitingPhase 2
Testing a new PET scan to detect brain tumor recurrence
This trial tests a special imaging scan called Ga-68 PSMA-11 PET/CT to see if it can better detect when a glioma brain tumor has come back or progressed. It is for people who have already had standard treatment and are planning surgery for a suspected recurrence.
Rochester, MinnesotaAges 18 years+ - NCT06446531RecruitingPhase 1
Preventing diabetes progression in Hispanic adults
This trial tests if a medication can prevent or slow the progression from prediabetes to type 2 diabetes and reduce heart risk. It is for Hispanic adults who are overweight and have prediabetes.
San Antonio, TexasAges 18 years+ - NCT06439836RecruitingPhase 1
Combination immunotherapy for advanced bladder cancer
This trial tests a new drug, CA-4948, combined with pembrolizumab (Keytruda) for people with advanced bladder cancer that grew after prior immunotherapy. The goal is to see if this combination can help when standard treatments stop working.
Duarte, CaliforniaAges 18 years+ - NCT06435000Recruiting
A study tracking Stargardt disease progression
This study follows people with Stargardt disease (a genetic eye condition that causes vision loss) over time. It aims to learn more about how the disease progresses and does not test any treatment.
San Diego, CaliforniaAges 12–65 - NCT06420219Recruiting
New head and neck cancer study for untreated patients
This study is looking at newly diagnosed head and neck cancer before any treatment begins. It will analyze your cancer's genes and other markers to understand how it develops and grows, which may help improve future care.
Los Angeles, CaliforniaAges 18 years+ - NCT06282848Recruiting
Myopia treatments for children ages 7 to 9
This study compares different ways to slow down nearsightedness (myopia) in children, including eyedrops and other treatments. It is designed for kids whose vision is getting worse and who are willing to join for 2 years.
Hong KongAges 7–9 - NCT04521972Recruiting
Testing how room light affects labor and uterine contractions
This study looks at whether changing the light you’re exposed to (using blue-filter glasses and adjusting lighting) changes uterine contractions and how labor progresses. You’d also track your lighting and use a home monitor that measures contraction activity.
East Lansing, MichiganAges 18–42 - NCT06390930Recruiting
Breathing bursts of lower oxygen for hand function in MS
This study tests whether breathing short bursts of reduced oxygen (acute intermittent hypoxia) can improve hand function and nerve health in people with relapsing-remitting MS who have some hand weakness.
Chicago, IllinoisAges 18–75 - NCT06380842Recruiting
Organ function after necrosectomy for pancreatitis with sepsis
This study looks at how a surgery to remove dead tissue from the pancreas (called open necrosectomy) affects organ function in patients with acute pancreatitis and sepsis. It may help doctors understand how to better treat this serious condition.
Chengdu, ChinaAges 18 years+ - NCT06382948RecruitingPhase 3
Elacestrant and everolimus for ESR1-mutant advanced breast cancer
This trial tests a new combination of two oral targeted therapy pills (elacestrant and everolimus) for people with a specific type of advanced breast cancer. It is for those whose cancer has an ESR1 mutation and has stopped responding to CDK4/6 inhibitors and hormone therapy.
InnsbruckAges 18 years+ - NCT04525833Recruiting
Visit Tzu Chi gastroenterology clinic study
This study looks at people who have visited a Tzu Chi Hospital gastroenterology clinic. It may help researchers understand liver and other whole-body health conditions in patients who receive care there.
New Taipei CityAges 18–99 - NCT06344000Recruiting
Nutrition and disease progression in bronchiectasis
This study looks at how nutrition affects the course of bronchiectasis, a lung condition that causes coughing and frequent infections. It may help find ways to slow the disease down.
Wuhan, HubeiAges 18–100 - NCT06349538Enrolling by invitation
Essential tremor subtypes and progression markers study
This study looks for biological markers to better understand different types of essential tremor and how the condition changes over time. It may help identify who has which subtype and predict disease progression.
Graz, AustriaAges 18 years+ - NCT06319027RecruitingPhase 2
Can brain scans help predict glioblastoma progression?
This trial is testing whether certain details on brain scans can help doctors better predict how brain cancer (glioblastoma) will progress. You may be eligible if you are newly diagnosed with this type of cancer and plan to receive standard treatment.
Birmingham, AlabamaAges 18 years+ - NCT05964829Recruiting
Test a leg sleeve to improve walking in multiple sclerosis
This trial studies whether using the Cionic “Neural Sleeve” can improve walking and leg movement in people with multiple sclerosis (MS). It may help if your MS affects mobility, and you can safely wear and tolerate the device during the day.
Cleveland, OhioAges 22–75
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 716 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.