Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 716 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06101290Recruiting
Local therapy for progressing spots in genitourinary cancers
This trial explores whether treating only the new or growing spots of cancer (called oligoprogression) with local therapies like radiation or ablation can help you stay on your current systemic treatment longer. It is for people with prostate, bladder, or kidney cancer that has started to progress in a few places.
Sacramento, CaliforniaAges 18 years+ - NCT06103669Recruiting
Local treatment for limited cancer spread
This trial tests whether using local treatments (like targeted radiation or ablation) on a few new spots of cancer can help people whose cancer is otherwise stable on their current treatment. It enrolls people with various solid tumors, such as breast, gynecologic, head & neck, sarcoma, or other types.
Sacramento, CaliforniaAges 18 years+ - NCT06093906Recruiting
Positive processes and transition to health (PATH) study
This study tests a new therapy that may help people recover after a stressful life event. Over about 6 weeks, you'll work with a coach to retrain your brain's patterns and feel more in control again, as well as reconnect with positive activities.
Newark, DelawareAges 18–65 - NCT06079567Recruiting
Study of FSHD2 progression over 18 months
This study follows people with FSHD2 over 18 months to learn how the disease progresses and affects daily life. No new drugs are tested—just regular check-ups and an MRI scan.
LeuvenAges 18–75 - NCT06065371RecruitingPhase 1
Sacituzumab govitecan plus capecitabine for advanced GI cancers
This trial tests a combination of two drugs—sacituzumab govitecan (targeted therapy) and capecitabine (chemotherapy)—for people with advanced stomach, colon, or pancreatic cancer that has stopped responding to standard treatments.
Detroit, MichiganAges 18 years+ - NCT06047171RecruitingPhase 2
Testing ALE.F02 for new kidney inflammation from vasculitis
This trial tests a new medicine called ALE.F02 for people newly diagnosed with a type of kidney inflammation called rapidly progressive glomerulonephritis (RPGN) caused by ANCA vasculitis. The goal is to see if it can help rescue kidney function.
PragueAges 18 years+ - NCT06034327Recruiting
Testing a new spectacle lens for slowing myopia in kids 6–8
This study tests a special spectacle lens designed to slow the progression of nearsightedness (myopia) in children aged 6 to 8. It may be a good option for kids who are mildly to moderately nearsighted and haven't used other myopia control treatments.
Oakland, CaliforniaAges 6–8 - NCT06046131Recruiting
Study on factors affecting prostate cancer progression in Guadeloupe and Brittany
This study looks at how genes, environment, and health history affect the growth of prostate cancer. It may help find better ways to treat the disease in people from the Caribbean and Brittany regions of France.
Rennes, Ille-et-VilaineAges 18 years+ - NCT04428554RecruitingPhase 2
Radiation to control bladder cancer spread after no growth
This trial tests whether giving focused radiation (SBRT) to a few remaining metastatic spots can stop bladder cancer from progressing after initial chemotherapy or immunotherapy has worked. It may help patients who still have up to three remaining distant lesions but are not getting worse.
AlbiAges 18 years+ - NCT06044025RecruitingPhase 1
Maintenance therapy for prostate cancer with rising PSA
This trial tests two medications (metformin and a turmeric compound) as a maintenance therapy for men with prostate cancer whose PSA is rising slowly after prior treatment. The goal is to see if these drugs can keep the cancer from growing while you take a break from standard hormone therapy.
Little Rock, ArkansasAges 18–100 - NCT06022146RecruitingPhase 3
Short TB prevention for school contacts
This trial tests a very short (one-month) medicine course to prevent tuberculosis (TB) in students and school staff who have been exposed to someone with active TB. If you have latent TB infection (the germs are in your body but you're not sick), this treatment aims to stop it from turning into active TB disease.
Anshun, GuiyangAges 13 years+ - NCT06007248Recruiting
Study of inflammation-related coronary artery disease
This study compares two types of coronary artery disease: one linked to inflammation (IR-CAD) and the standard type (AS-CAD). If you have had a heart procedure and were recently hospitalized for worsening chest pain, this study may help doctors understand your condition better.
Beijing, Beijing MunicipalityAges 45–64 - NCT06002581Recruiting
Using brain stimulation to slow Parkinson's disease progression
This study tests if a non-invasive brain stimulation technique called rTMS (repetitive Transcranial Magnetic Stimulation) can slow down Parkinson's disease by improving slow-wave sleep. It aims to help people with mild to moderate Parkinson's who are stable on their medication.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT05860400Recruiting
Testing add-on treatment to calm artery inflammation after heart procedures
This study looks at whether a comprehensive add-on treatment—starting with immune medicine and then a heart procedure when needed—can improve outcomes for people whose coronary artery disease is getting worse quickly. It focuses on cases where inflammation is likely driving new artery blockages or worsening chest pain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05948930Recruiting
Exercise and brain training for mild memory problems
This study tests whether a mix of physical exercise and computer brain training can improve working memory in people with mild cognitive impairment (MCI). It may help by strengthening memory skills and supporting brain health through supervised activity and computer-based practice.
Baltimore, MarylandAges 50–80 - NCT05955638Enrolling by invitation
Dual-focus contacts to slow worsening near-sightedness
This study tests whether dual-focus soft contact lenses can help slow how quickly myopia (near-sightedness) gets worse in young university students. You may be assigned either the dual-focus lens or a control lens, and you would need to wear the lenses most days for set hours.
Bradford, West YorkshireAges 18–21 - NCT05959005Recruiting
Tracking early macular atrophy changes in the eye
This study focuses on people age 50+ with early “wasting away” changes in the macula (central retina) called atrophic lesions. It aims to better understand how these early changes progress and how they affect vision testing, which may help improve future treatments.
Salt Lake City, UtahAges 50 years+ - NCT05946564RecruitingPhase 3
Pioglitazone to protect kidney function in ANCA vasculitis
This Phase 3 trial tests whether pioglitazone can help protect kidney function in people with newly diagnosed or relapsing ANCA-associated vasculitis that is actively affecting the kidneys. It aims to improve “renal tolerance,” meaning your kidneys may be better able to tolerate the disease and treatment.
AmiensAges 18–80 - NCT05926102Recruiting
Screening study for prostate cancer risk and access
This study looks at how genetic risk and regular screening can help find prostate cancer earlier. It may help you and other Veterans understand what screening is best for different risk levels and access needs.
Boston, MassachusettsAges 55–69 - NCT05940623Recruiting
Home eye pressure monitoring for glaucoma
This study tests whether measuring your eye pressure at home with a special device can help control glaucoma and slow its progression. It may offer a more convenient way to track your condition between doctor visits.
Wong Chuk HangAges 18 years+ - NCT05918263Recruiting
Exercise to slow prostate cancer in men on active surveillance
This trial tests whether moderate exercise can help keep low-risk prostate cancer from growing in men who are monitoring their cancer instead of treating it right away. It may be especially helpful for men with certain risk factors like obesity or being Black or African American.
Boston, MassachusettsAges 18 years+ - NCT05899439Recruiting
Blood test study of immune changes in type 1 diabetes
This study looks at how your immune system changes over time and how that relates to developing type 1 diabetes. You may be able to join if you can have blood drawn, since the study focuses on blood samples.
Gainesville, FloridaAges birth–100 years - NCT05867381Recruiting
Air purifier use to slow heart artery plaque in older adults
This trial tests whether using indoor air filtration at home can slow the progression of heart artery plaque-related problems in people with a past history of ischemic heart disease. It may help by improving indoor air quality, which the study links to inflammation in the body.
Los Angeles, CaliforniaAges 65–84 - NCT05828069RecruitingPhase 2
Tovorafenib for young people with worsening Langerhans cell histiocytosis
This Phase 2 trial tests tovorafenib (DAY101) to treat children and young people whose Langerhans cell histiocytosis (LCH) is getting worse, came back, or did not respond to prior treatment. It may help by targeting certain gene changes found in the LCH.
Birmingham, AlabamaAges 6 months–22 years
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 716 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.