Clinical trials
Prostate cancer clinical trials
Cancer of the prostate gland, one of the most common cancers in men. We’re tracking 1,212 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07424547RecruitingPhase 1
Study of SYS6043 for advanced or metastatic solid tumors
This trial tests a new study drug (SYS6043) for people with advanced or metastatic solid tumors that have not responded to or are not candidates for standard therapies. The drug targets a protein called B7-H3 on cancer cells to help stop tumor growth.
Plantation, FloridaAges 18 years+ - NCT07200830RecruitingPhase 3
Testing different schedules of a targeted radiation drug for advanced prostate cancer
This trial tests two different dosing schedules of a drug called Lutetium-177 PSMA RLT, which delivers radiation directly to prostate cancer cells. It is for men with advanced prostate cancer that has stopped responding to hormone therapy and has spread, who have not yet had chemotherapy for this stage of the disease.
Anchorage, AlaskaAges 18 years+ - NCT06945172Recruiting
Comparing quality of life after prostate removal vs. focal HIFU for prostate cancer
This study compares how two treatments—total prostate removal or focal HIFU (a targeted ultrasound therapy)—affect quality of life in men with favorable intermediate-risk prostate cancer who are sexually active. It aims to help patients choose the best option for their lifestyle.
Quint-FonsegrivesAges 40–75 - NCT06834204Enrolling by invitation
Better care coordination for cancer survivors
This study tests a program to improve communication between your cancer team and your regular doctor. If you have heart or diabetes risks and you're being treated for breast, prostate, bladder, or endometrial cancer, this trial may help coordinate your care.
New Brunswick, New JerseyAges 18 years+ - NCT04489719Recruiting
Testing whether DNA repair changes affect radium-223 response
This study looks at whether differences in a cancer’s DNA repair system can predict how well radium-223 works for men with prostate cancer that has spread to the bones. It may help researchers choose better treatment for people with bone metastatic, castration-resistant prostate cancer.
Baltimore, MarylandAges 18 years+ - NCT06685562Recruiting
Testing a map to help make cancer decisions together
This study tests a new way to help people with cancer and their doctors make decisions together. If you have prostate, breast, or melanoma cancer, this trial may help you understand your options better.
VejleAges 18 years+ - NCT06970275Recruiting
PET-CT imaging study for cancer surgery patients
This trial uses a special PET-CT scanner to take high-resolution images of cancer tumors that have been surgically removed. The goal is to see how well these images match the results from standard lab tests, such as pathology, and to track long-term outcomes.
AalstAges 18 years+ - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT06244004RecruitingPhase 2
PET-guided radiation for metastatic hormone-sensitive prostate cancer
This trial tests whether using a special PET scan (FDG-PET) to find and treat only the spots where cancer has spread with targeted radiation can help men with prostate cancer that has spread but still responds to hormone therapy. It compares standard treatment alone to standard treatment plus this targeted radiation.
Chicago, IllinoisAges 18 years+ - NCT06223022Enrolling by invitation
Nurse phone calls after cancer treatment ends
This trial tests whether regular phone calls from a nurse can help patients after they finish their main cancer treatment. It focuses on breast, colorectal, or prostate cancer that was treated with a goal to cure.
UmeåAges 18 years+ - NCT05918263Recruiting
Exercise to slow prostate cancer in men on active surveillance
This trial tests whether moderate exercise can help keep low-risk prostate cancer from growing in men who are monitoring their cancer instead of treating it right away. It may be especially helpful for men with certain risk factors like obesity or being Black or African American.
Boston, MassachusettsAges 18 years+ - NCT06785441Recruiting
Decision aid for older men considering active surveillance for prostate cancer
This study tests a decision aid to help men aged 65 and older with early-stage prostate cancer decide whether to choose active surveillance (monitoring the cancer instead of immediate treatment). The goal is to see if the tool helps men and their care partners make a more informed choice.
Houston, TexasAges 65 years+ - NCT07451002Recruiting
Study on Adherence to Apalutamide in Metastatic Hormone-Sensitive Prostate Cancer
This study looks at how well men with prostate cancer that has spread and is still hormone-sensitive stick to taking the drug apalutamide. It aims to understand real-world use and quality of life.
CaenAges 18 years+ - NCT06850545Recruiting
Lu-177 treatment for PSMA-positive metastatic prostate cancer
This trial tests a radioactive drug called Lutetium-177 (Lu-177) that targets and kills prostate cancer cells showing a specific marker (PSMA). It's for men with advanced prostate cancer that has spread and stopped responding to hormone therapy, and who have already tried certain chemotherapy or cannot have it.
Kuopio, Northern SavoniaAges 18 years+ - NCT07180381Recruiting
A closer look at prostate MRI to avoid unnecessary biopsies
This study uses repeat MRI scans to monitor men with an intermediate suspicion of prostate cancer, aiming to reduce unnecessary biopsies while still catching significant cancers early.
Emmen, DrentheAges 18 years+ - NCT07466498RecruitingPhase 2
Estrogen patch for men with metastatic prostate cancer
This study tests whether an estrogen patch can improve quality of life for men with prostate cancer that has spread. It may be an option if you haven't started certain hormone treatments yet.
Seattle, WashingtonAges 18 years+ - NCT05645510Recruiting
Study for people on long-term cancer targeted medicines
This study looks at people who are already taking long-term targeted cancer medicines. It may help researchers understand how these treatments work over time and whether there are ways to improve care.
Edmonton, AlbertaAges 18–90 - NCT02971085Recruiting
Registry for prostate cancer on active surveillance
This study follows men with low-risk prostate cancer who choose active surveillance (watching closely instead of immediate treatment). It aims to better track which monitoring results stay reassuring over time, and when treatment might be needed.
SeoulAges 40–80 - NCT05109910Recruiting
Checking lymph node surgery impact in men having prostate removal
This study looks at whether removing lymph nodes during prostate removal helps predict outcomes in men whose scans do not show spread. It may help improve how doctors decide who benefits from lymph node surgery based on your risk level and scan results.
AmsterdamAges 18 years+ - NCT05767307Recruiting
MRI for suspected prostate cancer in Denmark
This study is enrolling adults who have prostate cancer concerns and are being sent for an MRI scan. It aims to improve evaluation of suspected prostate cancer, which may help doctors decide next steps more accurately.
Aarhus N, AarhusAges 18–99 - NCT04642027RecruitingPhase 3
PSMA scan-guided salvage radiation after prostate surgery
This trial tests whether using a specialized PSMA PET scan to guide radiation can better treat prostate cancer that returns after prostate surgery. It targets the “prostate bed” area with a shorter, stronger radiation schedule (hypofractionated) to control rising PSA levels.
Arnhem, GelderlandAges 18–80 - NCT06585007RecruitingPhase 3
Radiation for limited cancer growth in castration-resistant prostate cancer
This trial tests whether giving focused radiation to limited areas of cancer growth (up to 3 spots) can help control the disease in men with castration-resistant prostate cancer. You may be eligible if your cancer is growing slowly and you are already on hormone therapy.
LeuvenAges 18 years+ - NCT07711314RecruitingPhase 2
Rezvilutamide after prostate removal for high-risk cancer
This trial tests if a daily pill called Rezvilutamide can prevent prostate cancer from returning in men who had their prostate removed and are at high risk of recurrence. It is for men who cannot or choose not to have radiation therapy.
Nanjing, JiangsuAges 18–75 - NCT07553780Recruiting
Tracking Prostate Cancer Response Using PSMA Imaging Scans
This study uses a special type of imaging scan (PSMA PET) to track how well prostate cancer treatment is working by comparing scans before and after your planned therapy. The goal is to help doctors better understand which treatments work best for your type of cancer.
Lanzhou, GansuAges 18 years+
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Common questions
- Are there clinical trials for prostate cancer?
- Yes. Clin2 currently lists 1,212 recruiting prostate cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.