Clinical trials
Psoriasis clinical trials
A skin condition that causes a rash with itchy, scaly patches. We’re tracking 161 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06030076Recruiting
Switching to tildrakizumab for moderate to severe psoriasis
This trial is for adults with moderate to severe plaque psoriasis who are currently on a biologic treatment (like Humira, Stelara, or Cosentyx) and are switching to tildrakizumab. It looks at how your quality of life and symptoms change after the switch.
Graz, StyriaAges 18 years+ - NCT07449702RecruitingPhase 2
Long-term safety study of ORKA-001 for plaque psoriasis
This study is a continuation for people who already took ORKA-001 for plaque psoriasis and did well. It tests whether staying on the medicine keeps helping without any new safety concerns.
Phoenix, ArizonaAges 18 years+ - NCT07401992RecruitingPhase 4
Semaglutide for psoriasis and weight management
This trial tests if semaglutide, a diabetes and weight-loss medication, can improve psoriasis symptoms and reduce inflammation. It may be an option for people with both psoriasis and overweight or obesity, with or without diabetes.
Monterrey, N.L.Ages 18 years+ - NCT07390487Recruiting
Audio therapy for anxiety in people with psoriasis
This study tests whether listening to a short audio program (about 25–30 minutes) at home can help reduce anxiety in people with psoriasis. If you have psoriasis and have been feeling anxious, you may be able to take part from home using your computer or phone.
San Francisco, CaliforniaAges 18 years+ - NCT07362017RecruitingPhase 3
Ponesimod for moderate to severe plaque psoriasis
This trial tests an investigational drug called ponesimod for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at improving skin symptoms.
Glendale, ArizonaAges 18–65 - NCT07337434RecruitingEarly Phase 1
Comparing two pills for moderate to severe psoriasis
This trial tests two oral medications, Apremilast and Methotrexate, to see which works better for people with moderate to severe plaque psoriasis. You must not have taken systemic treatments (pills or shots that work throughout the body) in the last 3 months.
Peshawar, Khyber PukhtunkhwaAges 18–60 - NCT07326813RecruitingPhase 3
Testing D-2570 for moderate to severe plaque psoriasis
This trial tests if a new oral medication called D-2570 can safely and effectively treat moderate to severe plaque psoriasis. It may be an option if your psoriasis covers a large area and has been stable for at least 6 months.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07320872Recruiting
Vaspin gene and blood levels in psoriasis patients
This study looks at the relationship between a gene (Vaspin) and the level of the Vaspin protein in the blood of people with psoriasis. It aims to help understand how psoriasis works and may point to new ways to treat it.
AswānAges 18–50 - NCT07298265Recruiting
Screening for psoriatic arthritis in people with psoriasis
This study compares two ways to find psoriatic arthritis (joint pain and swelling related to psoriasis) in people who only have psoriasis so far. Your answers to a simple questionnaire or a doctor's exam may help detect joint problems early.
Toronto, OntarioAges 18 years+ - NCT07289399Recruiting
Walking with diet for psoriasis and PCOS
This study tests whether adding treadmill walking to a diet plan helps women with psoriasis and PCOS who are obese. It compares the effects of diet alone versus diet plus walking on skin and hormone health.
Giza, DokkiAges 35–45 - NCT06231381RecruitingPhase 2
HB0034 for severe pustular psoriasis flare
This study tests an experimental drug called HB0034 for people with a sudden, severe flare of generalized pustular psoriasis (GPP). It aims to see if the drug can safely clear the pustules and improve symptoms.
BeijingAges 18–75 - NCT06893913Recruiting
Fasting plus exercise for dry eyes in psoriasis
This study tests whether adding a simple exercise (pyramidal exercise) to intermittent fasting can help reduce dry eyes in people who have psoriasis, prediabetes, and mild obesity. It aims to see if lifestyle changes can improve eye moisture.
Giza, DokkiAges 45–55 - NCT07261306RecruitingEarly Phase 1
Methotrexate vs tofacitinib pills for plaque psoriasis
This study compares two oral pill treatments—methotrexate and tofacitinib—for people with chronic plaque psoriasis that is moderate to severe and hasn't responded well to creams. The goal is to see which pill works better at clearing skin.
Lahore, Punjab ProvinceAges 18–70 - NCT07265284RecruitingPhase 3
IBI112 for teens with moderate to severe plaque psoriasis
This study tests a new medicine called IBI112 for teens aged 12–18 with moderate to severe plaque psoriasis. It aims to see if the medicine is safe and can help clear skin better than placebo.
Beijing, Beijing MunicipalityAges 12–18 - NCT07251998RecruitingPhase 2
A study of ICP-332 for moderate to severe plaque psoriasis
This trial tests an oral medication called ICP-332 versus a placebo (a pill with no active drug) for people with moderate to severe plaque psoriasis. The goal is to see if ICP-332 can improve skin symptoms and be safe.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07256015Recruiting
Deucravacitinib for moderate to severe psoriasis in Italy
This study looks at how well deucravacitinib works for people with moderate to severe plaque psoriasis in real-life settings in Italy. It follows patients who have already started the treatment to see how they are doing.
Verona, VeronaAges 18 years+ - NCT07250802RecruitingPhase 3
Long-term study of zasocitinib for children with plaque psoriasis
This trial tests a daily pill (zasocitinib) for children and teens with moderate to severe plaque psoriasis that hasn't been controlled by other treatments. It aims to see if the pill can safely improve skin symptoms over a long period.
Chula Vista, CaliforniaAges 4–17 - NCT07243782Recruiting
Study of Cosentyx for skin and joint conditions in Korea
This study tracks how well Cosentyx works in real-world use for people with hidradenitis suppurativa, plaque psoriasis, or juvenile idiopathic arthritis. It helps doctors understand the medicine's long-term effects in Korean patients.
Seoul, SeoulAges 6–100 - NCT07233291RecruitingPhase 2
Roflumilast pills for moderate to severe psoriasis in adults
This study tests an oral medicine called roflumilast for adults with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective when taken by mouth, and you can join if you have not used other systemic treatments recently.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07204639RecruitingPhase 2
Testing CBP-0276 for moderate to severe psoriasis
This trial tests a new medication, CBP-0276, to see if it improves psoriasis symptoms and quality of life. It is for people with moderate to severe plaque psoriasis who might need stronger treatment.
Mexico CityAges 18–70 - NCT07194200RecruitingPhase 2
Lactobacillus Plantarum for Psoriasis: Safety and Effectiveness Study
This trial tests whether a probiotic called Lactobacillus plantarum can safely help treat psoriasis. It's a randomized, double-blind study where some participants get the probiotic and others get a placebo, so no one knows who gets what.
Shenzhen, GuangdongAges 16–60 - NCT07187817Recruiting
Sequential biologic treatments for psoriasis
This trial looks at how different biologic treatments work when used one after another for people with plaque psoriasis. It may help find the best order of treatments to keep your skin clear.
Bath, SomersetAges 18 years+ - NCT07169019RecruitingEarly Phase 1
Probiotics and methotrexate for early psoriasis
This pilot study tests whether adding probiotics to standard methotrexate treatment improves symptoms in people newly diagnosed with chronic plaque psoriasis. It aims to see how the gut microbiome affects treatment response.
AlexandriaAges 18 years+ - NCT07129382RecruitingPhase 1/Phase 2
Study of CS32582 for moderate to severe plaque psoriasis
This trial tests a new oral medication, CS32582, for people with moderate to severe plaque psoriasis. It aims to see if the drug is safe and effective at reducing skin symptoms like redness, thickness, and scaling.
Beijing, Beijing MunicipalityAges 18–70
Hear when a new Psoriasis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for psoriasis?
- Yes. Clin2 currently lists 161 recruiting psoriasis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a psoriasis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a psoriasis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.