Clinical trials
Recurrence clinical trials
Below are recruiting recurrence clinical trials, each written for real people, not researchers. We’re tracking 1,423 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05962892Recruiting
Study of thyroid cancer return risk after heat ablation
This study looks at what makes papillary thyroid cancer come back after a heat-based treatment called thermal ablation. It may help doctors better predict recurrence risk and guide follow-up after treatment.
BeijingAges 18 years+ - NCT05963711Recruiting
Study penis microbiome in partners during vaginal microbiome treatment
This study looks at how the bacteria on a man’s penis may change during a woman’s vaginal microbiome transplant (VMT) for recurrent bacterial vaginosis (BV). You may be asked to follow condom and “decolonization” steps to help the researchers understand what works and why.
JerusalemAges 18 years+ - NCT05965024Recruiting
Using ctDNA blood tests to predict lung cancer return after surgery
This study checks whether a special blood test (ctDNA) taken before and after surgery can predict whether non-small cell lung cancer will come back. If it works, it may help doctors spot recurrence earlier and guide follow-up care after tumor removal.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05969574Recruiting
Study links miscarriage history to low egg supply
This study looks at whether having multiple early miscarriages is connected to having a lower egg supply. It compares miscarriage history with “ovarian reserve” in people seen at specific fertility clinics.
Abu Dhabi, Abu Dhabi EmirateAges Any age - NCT05974358Recruiting
Compare two bowel-connection methods to prevent Crohn’s flare-ups
This trial tests whether a specific type of bowel connection during Crohn’s surgery can lower the chances that the disease comes back. It may help people having their first ileocolonic (small-to-large bowel) surgery for certain Crohn’s complications.
BesançonAges 18–75 - NCT05979064Recruiting
Belly fat graft for recurrent brain tumor
This study tests if a piece of your own belly fat (omentum) placed in the brain during tumor surgery can help fight recurrent glioblastoma. It is for people who are already scheduled for surgery to remove their brain tumor.
New York, New YorkAges 18 years+ - NCT05982561Recruiting
Testing a urine test for bladder cancer recurrence
This trial tests a new urine test (BCDx) to see if it can catch bladder cancer coming back in people with non-muscle invasive bladder cancer (NMIBC) who are already having regular check-ups. You would give a urine sample before your routine cystoscopy, and the results may help doctors monitor your cancer more easily.
Little Rock, ArkansasAges 18 years+ - NCT05984576Recruiting
Chemo and radiation for recurrent rectal cancer after prior pelvic radiation
This study looks at combining total neoadjuvant therapy (chemotherapy and radiation) for rectal cancer that has come back in the pelvis after earlier radiation. It aims to see if this treatment approach can help control the disease and improve outcomes in patients with limited spread that can potentially be removed or treated.
RomeAges 18 years+ - NCT05990803RecruitingPhase 2
Testing new drugs for advanced cervical and gynecologic cancers
This trial tests a new drug called BL-B01D1, alone or combined with another drug (SI-B003), for people with cervical or other gynecologic cancers that have spread or come back after standard treatments. The goal is to see if this treatment can help when other options have stopped working.
Beijing, Beijing MunicipalityAges 18–75 - NCT06006039Recruiting
Study on immune cells and Crohn's disease recurrence after surgery
This study looks at how certain immune cells relate to Crohn's disease coming back after bowel surgery. The goal is to better understand why some patients have a recurrence, which could help improve future treatments.
Toronto, OntarioAges 18 years+ - NCT06006169RecruitingPhase 2
Study of new drugs for head and neck cancer and other solid tumors
This trial tests two new drugs, BL-B01D1 and SI-B003, alone or together, for people with head and neck squamous cell carcinoma that has come back or spread. It may also include other solid tumors. The goal is to see if these drugs can shrink tumors or slow their growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06011109RecruitingPhase 1/Phase 2
APG-157 plus Avastin for recurrent high-grade glioma
This trial tests a combination of two drugs—APG-157 (an oral plant-based medicine) and bevacizumab (Avastin)—for people with recurrent high-grade brain tumors that have already been treated with standard therapies. The goal is to see if adding APG-157 can help control the tumor better.
Rochester, MinnesotaAges 19 years+ - NCT06016465RecruitingEarly Phase 1
Nerve block plus steroid to prevent migraine return in 72 hours
This trial tests whether adding a steroid pill (dexamethasone) to a nerve block can stop a migraine from coming back within three days. It's for people whose headache got much better after a nerve block.
El Paso, TexasAges 18–85 - NCT06023719Recruiting
Study of Disc Care device for preventing repeat lumbar disc herniation
This trial tests a new device (Disc Care) implanted during surgery to repair a herniated disc in the lower back. It is designed to reduce the chance of the hernia coming back.
L'Hospitalet de Llobregat, BarcelonaAges 18–75 - NCT06023862RecruitingPhase 2
Study of dostarlimab and bevacizumab for recurrent clear cell cancer
This trial tests a drug called dostarlimab alone or with bevacizumab compared to standard chemotherapy for women whose clear cell cancer of the ovary, uterus, cervix, vagina, or vulva has come back within a year of platinum chemotherapy. The goal is to see if these newer treatments can help control the cancer better.
Clayton, Clayton Rd.Ages 18 years+ - NCT06031688RecruitingPhase 2
Targeted treatment for lung cancer with a MET gene change
This trial tests a targeted drug for advanced non-small cell lung cancer that has a specific genetic change called MET exon 14 skipping. It aims to see if the drug can shrink tumors or slow the cancer's growth, and may help people who have or haven't had prior treatment.
Daphne, AlabamaAges 18 minutes+ - NCT06037980RecruitingPhase 2/Phase 3
Chemotherapy before surgery for high-risk bile duct cancer
This trial tests whether receiving chemotherapy (cisplatin, gemcitabine, and nab-paclitaxel) before surgery can improve outcomes for people with high-risk bile duct or gallbladder cancer. It compares this approach to going straight to surgery.
AnconaAges 18–75 - NCT06042894RecruitingPhase 2
Study of two drugs for advanced HER2-negative breast cancer
This trial tests two experimental drugs, SI-B003 and BL-B01D1 plus SI-B003, for people with HER2-negative breast cancer that has spread or cannot be removed by surgery. It is for those who have tried standard treatments or cannot have them.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06046131Recruiting
Study on factors affecting prostate cancer progression in Guadeloupe and Brittany
This study looks at how genes, environment, and health history affect the growth of prostate cancer. It may help find better ways to treat the disease in people from the Caribbean and Brittany regions of France.
Rennes, Ille-et-VilaineAges 18 years+ - NCT06047197RecruitingPhase 1
RC19D2 cell therapy for advanced large B-cell lymphoma
This trial tests a new cell therapy called RC19D2 for people with diffuse large B-cell lymphoma that has not responded to standard treatments. The therapy uses your own immune cells that are modified to target and kill cancer cells.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06051695RecruitingPhase 1/Phase 2
CAR T cell therapy for mesothelin-positive solid tumors
This trial tests a new type of immune cell therapy (CAR T-cells) designed to target cancer cells that have a protein called mesothelin but have lost a marker that lets them hide from the immune system. It's for people with advanced solid tumors who have already tried standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT06055517Recruiting
Re-irradiation with low-dose pulses for recurrent glioma
This trial tests a new way to deliver radiation therapy for people whose brain tumor (glioma) has come back after earlier treatment. Instead of standard radiation, it uses very low doses given in pulses, which may be safer for patients who have already had radiation to the head.
Aviano, PordenoneAges 18 years+ - NCT06056297RecruitingPhase 3
Study of Mavorixafor for chronic neutropenia with infections
This trial tests if mavorixafor can help people with certain types of long-term low neutrophil counts (chronic neutropenia) who still get frequent or serious infections. It aims to reduce infection risk by boosting your body's infection-fighting cells.
Phoenix, ArizonaAges 12 years+ - NCT06058988RecruitingPhase 2
T-DXd for people with brain cancer
This trial tests a drug called Trastuzumab Deruxtecan (T-DXd) for people with brain tumors that are either glioblastoma or have spread from other cancers. Doctors will see if T-DXd can shrink tumors or slow their growth, and they will collect tumor tissue during surgery or biopsy to study how the drug works.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for recurrence?
- Yes. Clin2 currently lists 1,423 recruiting recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.