Clinical trials
Schizophrenia Spectrum Disorders clinical trials
Below are recruiting schizophrenia spectrum disorders clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05664789RecruitingPhase 2/Phase 3
N-acetylcysteine for autism behaviors in children
This trial studies whether N-acetylcysteine, a medicine taken by mouth, can improve autism-related restricted and repetitive behaviors in children. It looks at children who are showing at least moderate severity in these behaviors and may involve brain testing for safety reasons.
Palo Alto, CaliforniaAges 3–12 - NCT05546554RecruitingPhase 2
Suvorexant for sleep problems in teens with autism
This Phase 2 study tests whether suvorexant helps improve sleep in children and teens with autism who have significant sleep trouble. It may help reduce behaviors related to poor sleep by changing how the brain promotes sleep.
Stanford, CaliforniaAges 13–17 - NCT05540574RecruitingPhase 2
Zolpidem for sleep problems in autistic children
This Phase 2 study tests zolpidem (a sleep medicine) to help children with autism sleep better. It will check sleep changes using sleep testing and to confirm zolpidem is safe for this age group.
Stanford, CaliforniaAges 8–17 - NCT05501678RecruitingPhase 2
Diphenhydramine to help sleep in autistic children
This Phase 2 study tests whether diphenhydramine improves sleep in children with autism who have significant sleep problems. It requires sleep monitoring (watch data and sleep testing) and checking for side effects to see if the treatment is safe and helpful.
Stanford, CaliforniaAges 8–17 - NCT05185128Recruiting
Social skills training and brain imaging in teens with autism
This study looks at how social thinking and social skills training affect the brain in teens with autism, compared with teens with other severe mental health conditions and typically developing teens. It may help researchers understand what drives social difficulties and what could improve social functioning.
Loma Linda, CaliforniaAges 12–18 - NCT04278898RecruitingPhase 2
N-acetylcysteine to reduce repetitive behaviors in children with autism
This Phase 2 study tests whether a single dose of N-acetylcysteine can improve “restricted and repetitive behaviors” in children with autism. It’s meant for kids who are stable and still in early puberty stages.
Stanford, CaliforniaAges 3–12 - NCT03866668RecruitingPhase 2
Esomeprazole for young children with autism
This Phase 2 study tests whether esomeprazole helps children with autism. It looks at children who are generally healthy, take stable medicines, and can reliably attend visits so their care team can track changes during the study.
Stanford, CaliforniaAges 2–6 - NCT07121166Recruiting
Family therapy by video for schizophrenia
This trial tests a family therapy program delivered through video calls to help people with schizophrenia and their families. You would join group sessions with other families to learn ways to support each other and reduce stress.
Chai WanAges 18–64 - NCT07411222Recruiting
Emotional Eating, Sleep, and Metabolic Health Study
This study examines how emotional eating, sleep quality, and mental state relate to metabolic syndrome (a group of conditions like high blood pressure, high blood sugar, and extra belly fat) in people with stable schizophrenia or bipolar disorder. It aims to help understand and improve overall health.
Bolu, BoluAges 18–65 - NCT06569394RecruitingPhase 2
Testing CBD in young adults who use cannabis heavily
This study tests whether cannabidiol (CBD) can help young adults who use cannabis heavily but aren't looking to quit. You'll take a CBD pill and see if it changes your cannabis use or related symptoms.
Aurora, ColoradoAges 18–25 - NCT05703412Enrolling by invitation
Text or app check-ins after discharge for serious mental illness
This study tests an mHealth (phone-based) program that helps people with serious mental illness after leaving the hospital. It may help you stay connected to care and support in the community after discharge.
Providence, Rhode IslandAges 18 years+ - NCT04478838RecruitingPhase 4
Alternate-day antipsychotic dosing for schizophrenia
This trial looks at whether taking an antipsychotic every other day can keep symptoms controlled in adults with schizophrenia or another psychotic disorder. It may help some people avoid daily dosing, but it requires specific medication stability and screening checks.
Toronto, OntarioAges 18 years+ - NCT02916810Recruiting
TMS for persistent auditory hallucinations using a new setup
This study tests a specific brain stimulation approach (TMS) to help reduce auditory hallucinations in adults with schizophrenia who have not improved enough with medications. It may help by changing how the brain regions involved in hearing voices are stimulated.
Houston, TexasAges 18–50 - NCT07696871RecruitingPhase 1/Phase 2
Cannabidiol oil for treatment-resistant depression
This trial tests if cannabidiol (CBD) oil can help people with major depression that has not improved with standard antidepressants. You will take CBD oil or a placebo while continuing your current antidepressant treatment to see if it improves your symptoms.
Tubarão, Santa CatarinaAges 18–69
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Common questions
- Are there clinical trials for schizophrenia spectrum disorders?
- Yes. Clin2 currently lists 110 recruiting schizophrenia spectrum disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia spectrum disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia spectrum disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Schizophrenia Spectrum and Other Psychotic Disorders
- Schizophrenia and Schizophrenia Spectrum Psychosis
- Schizophrenia Disorders
- Schizophrenia and Related Disorders
- Fetal Alcohol Spectrum Disorders
- Neuromyelitis Optica Spectrum Disorders (NMOSD)
- Autistic Disorders Spectrum
- Schizophrenia and Other Psychotic Disorders
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.