Clinical trials · North Carolina
Sepsis clinical trials in North Carolina
We’re tracking 9 recruiting sepsis studies with a site in North Carolina — including Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in North Carolina
- NCT05304728Enrolling by invitation
Hospital sepsis decision support program enrollment study
This study tests a computer system meant to help doctors recognize and manage sepsis (a serious body-wide response to infection) when people come to the emergency department or are admitted to the hospital. If you’re evaluated in a hospital setting for possible sepsis, you may be included to help improve care decisions.
Raleigh, North CarolinaAges 18–89 - NCT07610486RecruitingPhase 1/Phase 2
Optimizing Ampicillin Dosing for Preterm Infants
This study aims to find the best dose of ampicillin for premature babies in the NICU who are being treated for possible early infection. The goal is to improve treatment and reduce side effects.
Durham, North CarolinaAges birth–1 week - NCT05267821RecruitingPhase 2/Phase 3
Testing anakinra to reduce inflammation in pediatric sepsis MODS
This study tests whether a medicine called anakinra can “turn down” harmful inflammation in children with severe illness from sepsis. It aims to improve organ function when multiple organs are starting to fail.
Durham, North CarolinaAges 1 day–17 years - NCT07215702RecruitingPhase 2
Testing a drug for kidney injury from sepsis in the ICU
This trial tests if a new drug, AZD4144, can help people with sepsis-related acute kidney injury in the ICU. It aims to see if the drug can improve kidney recovery and reduce complications.
Chapel Hill, North CarolinaAges 18–80 - NCT07425587Recruiting
Symphony IL-6 test for sepsis in the emergency room
This trial checks if a new blood test (Symphony IL-6) can help doctors quickly identify sepsis in patients coming to the emergency room. It may speed up diagnosis and treatment for serious infections.
Winston-Salem, North CarolinaAges 22 years+ - NCT07556107RecruitingPhase 4
Safety study of two antibiotics for serious hospital infections
This study watches how safely two common antibiotics (vancomycin and a combination called piperacillin/tazobactam) work together in hospitalized patients with serious infections. Researchers want to make sure the combination doesn't harm kidney function.
Winston-Salem, North CarolinaAges 18 years+ - NCT06072430RecruitingPhase 3
Testing a new fluid for septic shock with low blood pressure
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
Winston-Salem, North CarolinaAges 18 years+ - NCT06521502Recruiting
Studying inflammation in the heart and lungs in the ICU
This study collects blood samples from people in the ICU with sudden heart or lung problems caused by inflammation. The goal is to learn more about these conditions and improve future treatments.
Durham, North CarolinaAges 18 years+ - NCT02469662Recruiting
Study of outcomes after Nexel total elbow replacement
This study looks at how well the Nexel total elbow replacement works over time for people who need an elbow replacement due to pain, damage, or instability. It may help the doctors understand which patients benefit most and what results to expect.
Charlotte, North CarolinaAges 18 years+
Sepsis trials by city in North Carolina
Where these studies are running in North Carolina
Institutions with a site for the recruiting sepsis studies listed above.
- Duke University · 2 studies
- Wake Forest University Health Sciences · 2 studies
- Duke Health Neonatal Intensive Care Unit
- Novant Health
- OrthoCarolina Research Institute
- Research Site
- WakeMed Health & Hospitals
What taking part in a sepsis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Sepsis trials in other states
Common questions
- Are there sepsis clinical trials in North Carolina?
- Yes. We're currently tracking 9 recruiting sepsis studies with a site in North Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a sepsis study in North Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in North Carolina to take part?
- Not necessarily. These studies have a site in North Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a sepsis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New sepsis studies open in North Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.