Clinical trials
Shoulder clinical trials
Below are recruiting shoulder clinical trials, each written for real people, not researchers. We’re tracking 331 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06416618Recruiting
Surgery vs. No Surgery for Shoulder Fracture, Ages 50-65
This trial compares surgery versus non-surgical treatment for a broken shoulder bone (proximal humerus) in adults aged 50 to 65. It aims to find which approach leads to better recovery and function.
Køge, Region SjællandAges 50–65 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06292169Recruiting
Comparing two ways to release a muscle in reverse shoulder replacement
This trial tests if releasing a small chest muscle (the pectoralis minor) during reverse total shoulder replacement leads to better recovery or pain relief compared to not releasing it.
Atlanta, GeorgiaAges 18 years+ - NCT06154694Recruiting
Shoulder joint patterns in arthritis patients
This study looks at how shoulder arthritis affects joint movement patterns. It compares patients with arthritis, healthy volunteers, and people who had a shoulder replacement that later needed a revision.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06154889Recruiting
Rehab program after shoulder stabilization surgery (Latarjet)
This study tests a new rehab program after a shoulder stabilization surgery called Latarjet. It may help you recover better if you have had a dislocated shoulder and need this surgery.
AnnecyAges 18–67 - NCT02844738RecruitingPhase 2
Cell therapy for shoulder osteoarthritis pain and inflammation
This trial tests a treatment using your own (autologous) regenerative cells to reduce pain and inflammation from shoulder osteoarthritis. It may help people with long-lasting shoulder pain, but you must meet several health and medication timing requirements.
Grove City, PennsylvaniaAges 18–90 - NCT05978362Recruiting
Capsular repair value in Latarjet shoulder surgery
This trial compares two surgical methods for treating shoulder instability. It tests whether repairing the capsule (the tissue around the shoulder joint) provides extra benefit over the standard Latarjet procedure alone.
ParisAges 18 years+ - NCT05906004Recruiting
Follow-up study after Pitch-Patch shoulder repair
This study checks how well a Pitch-Patch device is doing to support the rotator cuff (a shoulder tendon). It enrolls people who had the device placed about 2 to 2.5 years ago so the researchers can follow outcomes and safety over time.
ReadingAges 16 years+ - NCT05675618Recruiting
Returning to Golf After Joint Replacement Surgery
This study focuses on helping people get back to golfing after common orthopedic (bone/joint) surgeries like hip or knee or shoulder replacement. You may be asked to complete follow-up questionnaires to track recovery and return-to-golf progress.
New York, New YorkAges 18 years+ - NCT05675527RecruitingPhase 4
Platelet gel (PRP) for shoulder arthritis pain
This trial tests whether platelet-rich plasma (PRP), a blood-based treatment, can reduce pain from shoulder (glenohumeral) osteoarthritis. It also looks at whether PRP works for people who had temporary relief from a numbing/shock injection into the joint.
New York, New YorkAges 18–100 - NCT05615259Recruiting
Compare personalized shoulder surgery with standard tools
This trial compares a personalized, guided approach to shoulder replacement (reverse shoulder arthroplasty) versus the usual surgical tools. It aims to see whether the guided method improves outcomes and implant performance over at least 2 years.
Gouda, HHAges 21 years+ - NCT04949087Recruiting
Shoulder arthritis injection study for ongoing pain relief
This trial looks at how well medicine given directly into the shoulder joint reduces pain from primary shoulder osteoarthritis. If you have ongoing shoulder pain confirmed by X-ray, you may be eligible to receive an in-joint injection and be followed for response.
Chicago, IllinoisAges 18 years+ - NCT04728282Recruiting
RTSA surgery with or without repairing the subscapularis
This study compares two surgical approaches for RTSA (reverse shoulder replacement): doing a tendon repair on the front of the shoulder or not. It may help show which approach leads to better recovery and shoulder function for people who need their first RTSA.
Winnipeg, ManitobaAges 18 years+ - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT03711175Enrolling by invitation
Repairing a shoulder tendon after reverse shoulder replacement
This study looks at whether repairing a specific shoulder tendon (the subscapularis) improves outcomes after reverse shoulder replacement. You may be eligible if you’re getting a reverse shoulder implant because of severe arthritis and your tendon is strong enough to repair on MRI.
St Louis, MissouriAges 21 years+ - NCT03704766Recruiting
Testing fluid markers to detect pediatric joint infections
This study checks special lab markers in joint fluid to tell septic (infected) arthritis apart from other inflammatory causes in children. It may help clinicians detect infection more accurately and quickly so kids can get the right treatment.
Atlanta, GeorgiaAges Up to 17 years - NCT03198702RecruitingPhase 3
Early botulinum shots to prevent shoulder shape problems
This trial tests whether early injections of botulinum toxin into a baby’s arm muscles can prevent the shoulder from changing shape in infants with obstetrical brachial plexus palsy (OBPP). It also checks that the injections are safe and effective over time.
BrestAges 10 months–11 months - NCT02996656Recruiting
Antibiotic prevention for skin bacteria in shoulder surgery
This study checks whether giving an antibiotic “ahead of surgery” can reduce problems from common skin bacteria (Propionibacterium acnes) during primary shoulder surgery. It may help lower the risk of infection around the new joint/repair.
Montreal, QuebecAges 18 years+ - NCT02503228Enrolling by invitation
Registry study of a preserved bone-cartilage graft
This registry study follows people who get a preserved graft to repair damaged bone and cartilage in a joint. It helps doctors understand how well the graft is preserved and how patients do after surgery over time.
Columbia, MissouriAges 13 years+
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Common questions
- Are there clinical trials for shoulder?
- Yes. Clin2 currently lists 331 recruiting shoulder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shoulder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shoulder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.