Clinical trials · Baltimore, MD
Sickle Cell Disease clinical trials in Baltimore
We’re tracking 37 recruiting sickle cell disease studies with a site in or near Baltimore — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Baltimore
- NCT05213572Recruiting
Study of organ health in adults with sickle cell
This observational study looks closely at how major organs (like brain, kidneys, heart, lungs, liver, and joints) are working in adults with sickle cell. It may help researchers understand what changes happen after curative treatments (like transplant or gene therapy) or with ongoing care.
Bethesda, MarylandAges 18–100 - NCT05099874Recruiting
Computer training to improve attention in sickle cell disease
This trial tests whether a computer-based “attention control” training program can improve attention and daily functioning in children with sickle cell disease. To join, you must meet certain criteria and also pass an initial attention screening test during the study.
Washington D.C., District of ColumbiaAges 8–16 - NCT06358638RecruitingPhase 2
Sickle cell transplant using a gentler approach for patients with donor antibodies
This trial is testing a new, gentler type of bone marrow transplant for children and young adults with sickle cell disease who have a healthy sibling donor with a mismatched blood type or who have antibodies against their donor's red blood cells. The goal is to replace the faulty bone marrow with healthy donor cells, with fewer side effects than traditional transplants.
Washington D.C., District of ColumbiaAges 2–25 - NCT06770010Recruiting
Digital brain training for kids with sickle cell disease
This trial is testing a digital program to help improve working memory (the ability to hold and use information in your mind) for children with sickle cell disease. If you join, you'll use a computer-based training program at home and researchers will see if it works and is easy to use.
Washington D.C., District of ColumbiaAges 7–16 - NCT06609226RecruitingPhase 3
Long-term safety study of etavopivat for sickle cell disease or thalassaemia
This study looks at the long-term safety and benefits of taking etavopivat for people with sickle cell disease or thalassaemia who have already been helped by it in a previous trial. It aims to see if staying on the treatment continues to be safe and effective.
Washington D.C., District of ColumbiaAges 2 years+ - NCT03587272RecruitingPhase 2
Sibling bone marrow transplant to reduce treatment side effects
This study tests a way to do a bone marrow (stem cell) transplant from an HLA-matched sibling in children with sickle cell disease, aiming to lower the risk of serious side effects. You may be considered if you have certain past sickle complications and your body can safely handle the transplant plan.
Washington D.C., District of ColumbiaAges 2–25 - NCT06612268RecruitingPhase 3
Testing etavopivat for sickle cell disease
This study tests an experimental pill called etavopivat for people with sickle cell disease who have had some pain crises in the past year. The goal is to see if it reduces these crisis episodes.
Washington D.C., District of ColumbiaAges 12 years+ - NCT06664541Enrolling by invitation
Gene therapy decisions and quality of life
This study looks at how people with blood diseases and their families make decisions about gene therapy, and how it affects their quality of life. It involves interviews or surveys to understand your experience.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04657822RecruitingPhase 4
Crizanlizumab rollover study for people with sickle cell disease
This study lets people with sickle cell disease who already finished a Novartis crizanlizumab trial continue treatment under a rollover plan. It’s designed for participants who benefited from crizanlizumab and completed the earlier study schedule without major ongoing side effects.
Washington D.C., District of ColumbiaAges 6 months–100 years - NCT06635902RecruitingPhase 2
Citrulline for sickle cell pain crisis
This trial tests if an intravenous medication called L-citrulline can help treat pain crises in children and young adults with sickle cell disease. Participants receive either the study drug or a placebo while in the hospital for a severe pain episode.
Washington D.C., District of ColumbiaAges 4–21 - NCT06941389Recruiting
Comparing stem cell transplant vs standard therapy for sickle cell disease
This study compares two treatment approaches for children with sickle cell anemia: a stem cell transplant from a matched family donor versus continuing regular disease-modifying medicines. It aims to see which treatment works better over time.
Washington D.C., District of ColumbiaAges 3–20 - NCT05775224Enrolling by invitation
Join a research data hub for sickle cell or multiple myeloma
This study builds a database of people with sickle cell disease and/or active multiple myeloma (diagnosed or treated in recent years). It may help researchers learn how these illnesses behave and support better future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT07023666RecruitingPhase 2
Early heart screening and treatment for sickle cell disease
This trial tests early screening and treatment to prevent heart problems in people with sickle cell disease. It focuses on those with high iron levels or heart symptoms, using regular heart imaging to monitor and treat complications early.
Falls Church, VirginiaAges 18 years+
Hear when a new Sickle Cell Disease trial opens near Baltimore, MD
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Sickle Cell Disease trials in other cities
Where these studies are running near Baltimore
Institutions with a site for the recruiting sickle cell disease studies listed above.
- Children's National Medical Center · 9 studies
- ASH Research Collaborative
- Georgetown University Medical Center
- Inova Fairfax Medical Campus
- MedStar Health
- National Institutes of Health Clinical Center
What taking part in a sickle cell disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting sickle cell disease studies in Maryland.
Common questions
- Are there sickle cell disease clinical trials near Baltimore?
- Yes. We're currently tracking 37 recruiting sickle cell disease studies with a site near Baltimore, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a sickle cell disease study near Baltimore?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Baltimore to take part?
- Not necessarily. These studies have a site near Baltimore, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a sickle cell disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New sickle cell disease studies open near Baltimore regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.