Clinical trials
Sickle Cell clinical trials
Below are recruiting sickle cell clinical trials, each written for real people, not researchers. We’re tracking 180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00081523Recruiting
Understanding How Sickle Cell Disease Develops Over Time
This research study follows people with sickle cell disease to learn how the condition affects their health over many years. By studying patients regularly, researchers hope to better understand the disease and improve care.
Washington D.C., District of ColumbiaAges 2–90 - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT02720679Recruiting
Study genetics behind blood disorders in children and families
This study looks at genetic (DNA) factors that may contribute to certain blood disorders. You may be invited if you or a close family member is receiving care for a blood condition like MDS or MPN, and the study also includes related relatives.
Memphis, TennesseeAges Any age - NCT00047996Enrolling by invitation
Blood Donation Study for Blood Vessel Research
This study collects blood and urine samples from adults to help researchers understand diseases affecting blood vessels. Your donation helps scientists develop better treatments.
Bethesda, MarylandAges 18–100 - NCT07442851Recruiting
SickleFit exercise and nutrition study for sickle cell
This study looks at whether a personalized exercise and nutrition program can help people with sickle cell disease feel better and have fewer pain crises. It is for adults 35 and older with any type of sickle cell disease.
Durham, North CarolinaAges 35 years+ - NCT07561957Recruiting
Smartphone app to help manage chronic kidney disease
This study tests a smartphone app designed to help people with chronic kidney disease (CKD)—a condition where the kidneys don't filter blood as well as they should—follow the latest medical guidelines. The app aims to make it easier for younger adults to stay on top of their kidney health and treatment.
DublinAges 16–30 - NCT07401823Enrolling by invitationPhase 2
Long-term follow-up study for sickle cell disease treatment
This study is a follow-up for people with sickle cell disease who already saw a benefit in fetal hemoglobin from the earlier Pioneer study. It tests the long-term safety and effects of the study drug pociredir (also called FTX-6058) while allowing most standard sickle cell treatments except hydroxyurea.
Little Rock, ArkansasAges 18 years+ - NCT06664541Enrolling by invitation
Gene therapy decisions and quality of life
This study looks at how people with blood diseases and their families make decisions about gene therapy, and how it affects their quality of life. It involves interviews or surveys to understand your experience.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06300723Enrolling by invitation
BRL-101 for severe sickle cell disease
This trial tests a new treatment called BRL-101 for people with severe sickle cell disease. The treatment uses your own stem cells, which are modified in the lab and then given back to you. It aims to reduce pain crises and improve your quality of life.
Nanning, GuangxiAges 3–35 - NCT05775224Enrolling by invitation
Join a research data hub for sickle cell or multiple myeloma
This study builds a database of people with sickle cell disease and/or active multiple myeloma (diagnosed or treated in recent years). It may help researchers learn how these illnesses behave and support better future studies or treatments.
Washington D.C., District of ColumbiaAges Any age - NCT04432623Enrolling by invitationPhase 1/Phase 2
Test drug for adults with beta thalassemia intermedia
This trial studies an investigational medicine in adults with beta thalassemia intermedia (including non-transfusion dependent thalassemia). The goal is to see how well the treatment works and how safe it is for people whose hemoglobin runs in a certain range.
Oakland, CaliforniaAges 18 years+ - NCT03948867Enrolling by invitationPhase 2
Hydroxyurea to help prevent strokes in sickle cell
This study looks at whether hydroxyurea (a medicine) can help lower the risk of stroke in children with sickle cell anemia, using screening tests like ultrasound of blood flow. It may help by identifying kids at higher risk and starting treatment if it’s safe for them.
Cincinnati, OhioAges 2–16
Hear when a new Sickle Cell trial opens
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Common questions
- Are there clinical trials for sickle cell?
- Yes. Clin2 currently lists 180 recruiting sickle cell studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sickle cell trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sickle cell trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.