Clinical trials
Stress and Anxiety clinical trials
Below are recruiting stress and anxiety clinical trials, each written for real people, not researchers. We’re tracking 179 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07315516RecruitingPhase 2
Sleep and stress supplement study
This study tests a new supplement to help with sleep and stress. It is for adults who feel stressed and have sleep problems, but are otherwise healthy.
BrisbaneAges 18 years+ - NCT06289621Recruiting
Brief treatment for anxiety and PTSD in South Africa
This trial tests a short, talk-based therapy for people with anxiety disorders or PTSD. It aims to help you manage symptoms in fewer sessions.
Cape TownAges 18–65 - NCT06557083Recruiting
Exercises to lower stress in PT students
This trial tests whether doing simple, daily 'polyvagal' exercises (gentle activities that help calm your nervous system) can lower stress for physical therapy students.
Orangeburg, New YorkAges 18–45 - NCT05466851Recruiting
Study testing anxiety and depression biology and therapy markers
This study looks at “biopsychosocial markers” (biological, psychological, and social signs) in people with major depression and/or anxiety. It aims to understand what changes with treatment and how those changes connect to symptoms like anxiety and depression.
New York, New YorkAges 18–65 - NCT05895006Recruiting
Study brain responses in PTSD using stimulation and brain scans
This study looks at how anxiety and stress show up in the brain in people with PTSD, using brain stimulation and brain scanning. If you’re eligible, it may help researchers understand your symptoms and how they relate to brain activity.
Houston, TexasAges 18–50 - NCT06362538Recruiting
Heart health prevention program
This trial tests a program to help prevent heart problems in people who have not had a heart attack or stroke. It is for adults aged 30 and older.
Cotignola, RavennaAges 18–30 - NCT06080100RecruitingEarly Phase 1
Xenon sedation for stress relief before eye surgery
This study tests whether a calming gas called xenon can help reduce stress and anxiety before a specific type of laser eye surgery (SMILE). It may help people who feel very nervous or anxious before their procedure.
KrasnodarAges 18–45 - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT06358612Recruiting
Stress ball for anxiety during thyroid biopsy
This study tests whether using a stress ball during a thyroid biopsy can help reduce anxiety. It's for people having their first thyroid biopsy with only one lump to be checked.
Halifax, Nova ScotiaAges 18 years+ - NCT07415460Recruiting
SKY breath meditation study for college student stress
This study tests if a breathing technique called SKY Breath Meditation can help college students feel less stressed and more connected. You would attend a weekend retreat and join online sessions over 8 weeks.
Tuscaloosa, AlabamaAges 18 years+ - NCT05527509Recruiting
Study of risk and resilience in new RCMP cadets
This study follows people as they start RCMP Cadet Training to learn what factors affect “risk” and “resilience” (how well someone adapts under stress). It may help improve support for cadets during training.
Regina, SaskatchewanAges 19–57 - NCT06523413Recruiting
Games and stress balls for anxiety after knee surgery
This study tests whether playing a game or squeezing a stress ball can help reduce anxiety and keep your vital signs (like heart rate and blood pressure) stable after knee replacement surgery. It is designed for people who are having a total knee replacement and can understand Turkish.
IspartaAges 18 years+ - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+ - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT06789250Recruiting
Online therapy for mental health and alcohol use issues
This trial tests an internet-based cognitive behavioral therapy program designed for people who struggle with both mental health symptoms (like depression or anxiety) and problematic alcohol use. The goal is to see if this approach can help improve both issues at the same time, conveniently from home.
LinköpingAges 18 years+ - NCT03896529Recruiting
Study how aging and stress affect memory navigation
This study uses brain imaging (MRI) and controlled stimulation to understand how normal aging and stress affect memory and thinking, including how people navigate. It may help researchers learn what changes in the brain happen over time and with stress.
Atlanta, GeorgiaAges 65–80 - NCT07338292Recruiting
Virtual reality for pain and anxiety in urology procedures
This study tests if using virtual reality can reduce pain and anxiety during outpatient urology procedures like circumcision, prostate biopsy, or flexible cystoscopy. If you are having one of these procedures for the first time, you may be able to participate.
PadovaAges 18–99 - NCT07319117Recruiting
Can a nutritional drink help your brain under stress?
This study tests whether a special nutritional drink can help your brain work better when you're under stress. If you're a healthy woman in her 40s or 50s who drinks coffee daily, you may be able to join.
Leeds, West YorkshireAges 40–60 - NCT06584253Recruiting
Digital addiction study for university students
This study looks at how university students use smartphones and whether they develop digital addiction. It's a simple survey-based study to understand patterns and risks.
Iğdır, IğdırAges 18 years+ - NCT07341425Recruiting
Focused therapy for stress, anxiety, and depression
This trial tests a short, online therapy program (Focused Acceptance and Commitment Therapy) designed to help you manage stress, anxiety, or depression. You can participate from home using a smartphone, tablet, or computer with a camera.
Aarhus CAges 18 years+ - NCT04130269Recruiting
Study of stress, anxiety, and pain after heart attack
This study looks at how anxiety, stress, and pain may affect people after a heart attack. It may help researchers understand who could benefit from supportive strategies after myocardial infarction (heart attack).
Graz, StyriaAges 19–90 - NCT05288140Recruiting
Using daily diaries for people in the intensive care unit
This study checks whether keeping a daily diary for people in the intensive care unit can help after an ICU stay. You may be eligible if you are in the ICU, are sedated and on a breathing machine for at least 24 hours, and can agree to follow-up visits.
BarcelonaAges 18–100 - NCT05765162Recruiting
Research study on safer, more tailored anesthesia
This study looks at safer anesthesia—meaning medicines used during procedures—using a more personalized approach. It may help make anesthesia safer for adults having medical procedures.
Nykøbing FalsterAges 18–100 - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+
Hear when a new Stress and Anxiety trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for stress and anxiety?
- Yes. Clin2 currently lists 179 recruiting stress and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.