Clinical trials
Stress and Anxiety clinical trials
Below are recruiting stress and anxiety clinical trials, each written for real people, not researchers. We’re tracking 167 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07315516RecruitingPhase 2
Sleep and stress supplement study
This study tests a new supplement to help with sleep and stress. It is for adults who feel stressed and have sleep problems, but are otherwise healthy.
BrisbaneAges 18 years+ - NCT06289621Recruiting
Brief treatment for anxiety and PTSD in South Africa
This trial tests a short, talk-based therapy for people with anxiety disorders or PTSD. It aims to help you manage symptoms in fewer sessions.
Cape TownAges 18–65 - NCT05466851Recruiting
Study testing anxiety and depression biology and therapy markers
This study looks at “biopsychosocial markers” (biological, psychological, and social signs) in people with major depression and/or anxiety. It aims to understand what changes with treatment and how those changes connect to symptoms like anxiety and depression.
New York, New YorkAges 18–65 - NCT05895006Recruiting
Study brain responses in PTSD using stimulation and brain scans
This study looks at how anxiety and stress show up in the brain in people with PTSD, using brain stimulation and brain scanning. If you’re eligible, it may help researchers understand your symptoms and how they relate to brain activity.
Houston, TexasAges 18–50 - NCT07871916Recruiting
Mindfulness app for parents going through divorce or separation
This study tests a mindfulness app designed to help parents manage stress during divorce or separation. It may help you feel calmer and more focused as you navigate this challenging time.
Stamford, ConnecticutAges 18 years+ - NCT06362538Recruiting
Heart health prevention program
This trial tests a program to help prevent heart problems in people who have not had a heart attack or stroke. It is for adults aged 30 and older.
Cotignola, RavennaAges 18–30 - NCT07844395Recruiting
Stress ball for pain and anxiety during breast biopsy
This study tests whether squeezing a small ball (stress ball) during a breast biopsy can help reduce pain, anxiety, and changes in heart rate and blood pressure. If you are having your first breast biopsy, you may be able to participate and help learn if this simple technique improves comfort.
KayseriAges 18 years+ - NCT07507656Recruiting
Stress ball for anxiety before kidney stone surgery
This study tests whether squeezing a stress ball before your kidney stone surgery can help lower your anxiety and fear, and keep your heart rate and blood pressure more stable during the procedure.
Yenişehir, MersinAges 18 years+ - NCT07382323Recruiting
Comparing two talk therapies for anxiety and PTSD
This trial tests two types of therapy — metacognitive therapy and cognitive-behavioral therapy — to see which works better for people with certain anxiety disorders or PTSD. You would be randomly assigned to one of the treatments and attend regular sessions.
StockholmAges 18 years+ - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT06358612Recruiting
Stress ball for anxiety during thyroid biopsy
This study tests whether using a stress ball during a thyroid biopsy can help reduce anxiety. It's for people having their first thyroid biopsy with only one lump to be checked.
Halifax, Nova ScotiaAges 18 years+ - NCT07415460Recruiting
SKY breath meditation study for college student stress
This study tests if a breathing technique called SKY Breath Meditation can help college students feel less stressed and more connected. You would attend a weekend retreat and join online sessions over 8 weeks.
Tuscaloosa, AlabamaAges 18 years+ - NCT05527509Recruiting
Study of risk and resilience in new RCMP cadets
This study follows people as they start RCMP Cadet Training to learn what factors affect “risk” and “resilience” (how well someone adapts under stress). It may help improve support for cadets during training.
Regina, SaskatchewanAges 19–57 - NCT06523413Recruiting
Games and stress balls for anxiety after knee surgery
This study tests whether playing a game or squeezing a stress ball can help reduce anxiety and keep your vital signs (like heart rate and blood pressure) stable after knee replacement surgery. It is designed for people who are having a total knee replacement and can understand Turkish.
IspartaAges 18 years+ - NCT06633146Recruiting
Stroke rehab in nature settings
This trial tests if stroke recovery exercises in natural environments can help improve your rehabilitation. It is for people who have had a recent stroke.
LahtiAges 18 years+ - NCT06538246Recruiting
Coping skills training for heart and lung failure survivors
This study tests a coping skills training program to help people who recently survived a serious heart or lung problem feel less anxious, depressed, or stressed. If you were in the ICU and now feel distressed at home, you may be able to join.
Durham, North CarolinaAges 18 years+ - NCT06789250Recruiting
Online therapy for mental health and alcohol use issues
This trial tests an internet-based cognitive behavioral therapy program designed for people who struggle with both mental health symptoms (like depression or anxiety) and problematic alcohol use. The goal is to see if this approach can help improve both issues at the same time, conveniently from home.
LinköpingAges 18 years+ - NCT03896529Recruiting
Study how aging and stress affect memory navigation
This study uses brain imaging (MRI) and controlled stimulation to understand how normal aging and stress affect memory and thinking, including how people navigate. It may help researchers learn what changes in the brain happen over time and with stress.
Atlanta, GeorgiaAges 65–80 - NCT07338292Recruiting
Virtual reality for pain and anxiety in urology procedures
This study tests if using virtual reality can reduce pain and anxiety during outpatient urology procedures like circumcision, prostate biopsy, or flexible cystoscopy. If you are having one of these procedures for the first time, you may be able to participate.
PadovaAges 18–99 - NCT07319117Recruiting
Can a nutritional drink help your brain under stress?
This study tests whether a special nutritional drink can help your brain work better when you're under stress. If you're a healthy woman in her 40s or 50s who drinks coffee daily, you may be able to join.
Leeds, West YorkshireAges 40–60 - NCT05288140Recruiting
Using daily diaries for people in the intensive care unit
This study checks whether keeping a daily diary for people in the intensive care unit can help after an ICU stay. You may be eligible if you are in the ICU, are sedated and on a breathing machine for at least 24 hours, and can agree to follow-up visits.
BarcelonaAges 18–100 - NCT07630623Enrolling by invitation
Relaxation and grip exercises for pregnant women with preeclampsia
This study tests whether two simple exercises—progressive muscle relaxation (tensing and releasing muscle groups) and finger grip exercises—can help pregnant women with preeclampsia manage stress, anxiety, fatigue, and sleep problems. Preeclampsia is high blood pressure during pregnancy that needs careful monitoring.
Ordu, AltinorduAges 18 years+ - NCT07561515Enrolling by invitation
Sound Therapy for Anxiety, Stress, and Depression
This study tests whether listening to specially designed sound can help reduce anxiety, stress, or depression. You'll participate for 3 weeks and answer questionnaires about how you feel.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07560241Enrolling by invitation
Art Therapy to Help Nursing Students With Stress and Mood
This study tests whether an art therapy program can help nursing students manage depression, anxiety, and stress. You'll participate in art therapy sessions and complete surveys about your mood and emotional skills.
Istanbul, IstanbulAges 17–23
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Common questions
- Are there clinical trials for stress and anxiety?
- Yes. Clin2 currently lists 167 recruiting stress and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.