Clinical trials
Supplementation clinical trials
Below are recruiting supplementation clinical trials, each written for real people, not researchers. We’re tracking 671 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07416786Recruiting
Testing NAD+ levels in healthy young and older adults
This study measures NAD+ (a molecule linked to aging) in healthy adults aged 18-35 or 70+. It will help researchers understand how NAD+ changes with age and if supplements like NR affect it.
Philadelphia, PennsylvaniaAges 18–110 - NCT07412444Recruiting
Olive oil study for fatty liver health
This trial tests if extra virgin olive oil (EVOO) can improve liver health in people with metabolic fatty liver disease (MASLD). It may help reduce fat in the liver and improve overall metabolic health.
Castellana Grotte, ItalyAges 18–65 - NCT06826222Recruiting
Sodium bicarbonate for better running performance in women
This study tests whether taking sodium bicarbonate (a common food ingredient) before a run can help women runners perform better in endurance events like a 10 km race. It is for recreational female runners who already run at a good pace.
Ankara, AnkaraAges 18–40 - NCT07400367Recruiting
Probiotics and lifestyle changes for fatty liver disease
This trial tests whether taking probiotics plus making lifestyle changes can improve fatty liver and metabolic health. You may qualify if you have liver fat and at least one sign of metabolic problems like high blood sugar or high blood pressure.
New Taipei CityAges 18–80 - NCT07399886Recruiting
Plant or dairy shake for cancer and heart patients at risk of malnutrition
This study compares two types of nutrition shakes (one plant-based and one dairy-based) for patients who are undernourished due to cancer, lung disease, heart problems, or recovery from surgery. It aims to see if the plant-based shake is just as good as the dairy shake.
Nijmegen, GelderlandAges 18 years+ - NCT07405554RecruitingPhase 2
Zinc with botox for overactive bladder
This trial tests whether taking zinc along with a botox injection (a standard treatment) can better reduce sudden, strong urges to urinate in women with overactive bladder who haven't gotten relief from other treatments.
Skokie, IllinoisAges 21–100 - NCT06531863RecruitingEarly Phase 1
Curcumin and green tea supplement for mood improvement
This study tests whether taking curcumin (found in turmeric) and EGCG (found in green tea) can improve mood and increase a brain protein called BDNF, which may help with depression. It is for adults ages 18 to 50 with mild to moderate depression symptoms.
Auburn, AlabamaAges 18–50 - NCT07397572Recruiting
Iron pills and anemia after sleeve gastrectomy
This study tests whether giving iron supplements after sleeve gastrectomy surgery helps prevent or treat anemia. It may be a good fit if you are planning to have this weight-loss surgery and can commit to 6 months of follow-up.
Cairo, Al-Manial CairoAges 18–65 - NCT06045351RecruitingPhase 1
Vitamin D shots for women with PCOS and low vitamin D
This trial tests whether vitamin D injections can help females with polycystic ovary syndrome (PCOS) who also have low vitamin D levels. Participants will receive the injection and be monitored for changes in their condition.
Karachi, SindhAges 18–45 - NCT07383974Recruiting
12-week study: how diet affects skin and health
This trial tests whether eating more fruits and vegetables for 12 weeks can improve your skin and how you feel physically. It uses a special light scanner to measure skin health.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07380412Recruiting
Supplement study for ADHD med side effects
This trial tests if a dietary supplement can help reduce common side effects of stimulant medications for ADHD, like trouble sleeping or feeling irritable. If you take a stable dose of ADHD medication and are dealing with these issues, you may be able to join.
Las Vegas, NevadaAges 18–55 - NCT07383311Recruiting
Natural supplements for memory and sleep
This study tests whether certain natural compounds (autophagy enhancers) can improve sleep in people with age-related memory concerns, including those with mild cognitive impairment and those with only subjective declines.
Greifswald, Mecklenburg-VorpommernAges 55–75 - NCT07383701RecruitingPhase 2
Probiotic for diabetic macular edema
This trial tests whether a daily probiotic supplement (Lactiplantibacillus plantarum 299v) can help improve diabetic macular edema, a swelling in the back of the eye caused by diabetes. The goal is to see if adding this probiotic to your regular care could reduce swelling and protect your vision.
Boston, MassachusettsAges 18 years+ - NCT07381998Enrolling by invitation
Effects of total thyroid removal on parathyroid function and quality of life
This study looks at how completely removing the thyroid gland affects the nearby parathyroid glands (which control calcium) and your overall quality of life. If you're having a total thyroid removal and meet a few health conditions, you may be able to join.
Aarhus, Central JutlandAges 18 years+ - NCT07374042RecruitingPhase 3
A supplement to protect muscle in advanced kidney disease
This trial tests whether a special diet supplement (Ketoanalogue) can help protect your muscles while you follow a moderate protein diet. It is for people with chronic kidney disease stage 4 or 5 who are not on dialysis or have not had a kidney transplant.
Clermont-FerrandAges 18–100 - NCT07378033Enrolling by invitation
Body fat reduction and weight management study
This study tests a new approach to help with weight loss and body fat reduction. It may be a good fit if you are an adult with a BMI in the overweight to moderately obese range and you are not currently using weight-loss medications.
Bangalore, KarnatakaAges 19–65 - NCT06151392RecruitingPhase 4
Probiotics and zinc for children with brain infection
This trial tests whether adding probiotics (healthy bacteria) and zinc supplements to standard treatment helps children with a brain infection called ventriculitis. It aims to see if these supplements improve recovery and reduce complications.
CairoAges 1 month–4 years - NCT07364162RecruitingPhase 2
Ketone drink for confusion in intensive care patients
This trial tests whether giving a special ketone drink to patients in the ICU can reduce or treat delirium (confusion). If you or a loved one is in the ICU, this treatment might help clear up confusion faster.
Nashville, TennesseeAges 18 years+ - NCT07367412Recruiting
Zinc supplements for infection prevention in older hospital patients
This study tests whether giving zinc supplements to older patients (65+) in the hospital can help prevent infections. It is for patients at Herlev Hospital who are not already taking high doses of zinc or receiving certain specialized treatments.
Herlev, CopenhagenAges 65 years+ - NCT06062017Recruiting
Potassium, hydration, and heart health in young adults
This study looks at how potassium and hydration affect heart and kidney health in healthy young adults. It may help you understand your own health and contribute to new knowledge about preventing disease.
Auburn, AlabamaAges 18–30 - NCT07355634Recruiting
Terraflora daily care for gut health
This trial tests if a daily probiotic supplement, Terraflora, can improve gut health in people with an imbalance of gut bacteria (dysbiosis). You may join if you're an adult with a stool test showing dysbiosis and are not taking certain other medications or supplements.
Richmond, VirginiaAges 25 years+ - NCT07359625Recruiting
Study on ketone drinks and insulin health
This study tests if drinking a ketone supplement can improve how your body responds to insulin, which affects blood sugar control.
Aarhus NAges 55–70 - NCT04331639Recruiting
High-dose vitamin D for kids with IBD on biologic therapy
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Boston, MassachusettsAges 5–25 - NCT07344636Recruiting
NR supplements and zone 2 training for metabolism
This trial tests whether taking nicotinamide riboside (a vitamin-like supplement) helps your body burn fuel better during moderate exercise, known as zone 2 training. It may benefit healthy adults who want to improve their workout efficiency.
Hong Kong, Please SelectAges 18–80
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Common questions
- Are there clinical trials for supplementation?
- Yes. Clin2 currently lists 671 recruiting supplementation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a supplementation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a supplementation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.