Clinical trials
Supplementation clinical trials
Below are recruiting supplementation clinical trials, each written for real people, not researchers. We’re tracking 700 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07299006Recruiting
Study of a robot to help manage pain during IV placement in children
This trial tests whether a friendly robot named Paro can help reduce pain and anxiety in young children when they need an IV placed. If your child is between 1 and 7 years old and needs an IV, this study may help make the procedure less stressful.
BrestAges 1–7 - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65 - NCT07173049Recruiting
Speech help for kids using a communication board
This study tests whether a communication board can help children with cerebral palsy or similar conditions speak more clearly. It is designed for kids who have trouble being understood but can still say a few words.
Madison, WisconsinAges 7–17 - NCT07736547Enrolling by invitation
AI-guided supplement for weight loss
This study tests a nutritional supplement (guided by your gut bacteria) to help with weight loss, along with lifestyle advice. It might be a good fit if you are overweight but not diabetic and have not used weight-loss medications recently.
IstanbulAges 18–65 - NCT06612762Recruiting
Naringenin supplements for bone fracture recovery
This trial tests whether taking naringenin, a natural supplement found in citrus fruits, can help improve healing after a broken leg bone surgery. It is for adults who could walk without help before their injury.
TehranAges 18–60 - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT07715955Recruiting
Can probiotics help control appetite in adults with overweight or obesity?
This study tests whether taking probiotics can help regulate appetite in people who are overweight or have obesity. It aims to understand if these supplements can support weight management by affecting hunger and fullness signals.
Maastricht, LimburgAges 20–70 - NCT04118387RecruitingPhase 4
Study of how to treat central sleep apnea in Veterans
This Phase 4 study looks at what’s going on in the body during central sleep apnea and uses that information to guide treatment. If you have central sleep apnea, this could help confirm or improve how treatment is chosen for you.
Detroit, MichiganAges 18 years+ - NCT07668596Recruiting
Broccoli sprout supplement and exercise in healthy adults
This trial studies how a natural compound from broccoli sprouts (sulforaphane) and exercise, alone or together, affect your body's immune and metabolic health. It's for healthy, active adults aged 19–35.
Kelowna, British ColumbiaAges 19–35 - NCT07149649RecruitingPhase 2/Phase 3
Magnesium for advanced lung cancer
This trial tests if adding magnesium supplements to standard first-line treatment (chemotherapy plus immunotherapy) improves outcomes for people with advanced non-small cell lung cancer (NSCLC) that has spread or cannot be removed by surgery. It is for patients who have not had prior treatment for metastatic disease.
AarauAges 18 years+ - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT03059173RecruitingPhase 3
Myo-inositol to help women with PCOS get pregnant
This trial tests whether taking myo-inositol helps women with PCOS improve fertility and get pregnant. It compares outcomes in women who have not used the common fertility medicine clomiphene citrate (CC) recently.
LilleAges 18–35 - NCT03201094Recruiting
NMES and whey protein for recovery after aneurysmal brain bleed
This pilot study tests whether a therapy that gently stimulates nerves (NMES) and a whey-protein supplement (HPRO) can improve recovery after an aneurysmal subarachnoid hemorrhage (SAH), a type of bleeding around the brain. Participants are usually treated soon after the bleed and stay in the ICU long enough for the study measures.
Baltimore, MarylandAges 18 years+ - NCT03322891Recruiting
Helping African-American men understand prostate cancer care
This study tests an approach to improve health understanding for African-American patients with early-stage prostate cancer. It may help you communicate better with your care team and feel more confident managing your diagnosis and next steps.
Atlanta, GeorgiaAges 25–100 - NCT03581773RecruitingPhase 2
Folic acid to reduce mouth sores during kidney cancer treatment
This Phase 2 trial tests whether folic acid can lessen mucositis (painful mouth sores) caused by certain kidney cancer medicines. You would either take folic acid or an inactive pill, and the study looks for improvement in these side effects.
Aarhus, Central Region of DenmarkAges 18 years+ - NCT03649698Recruiting
Exercise and nutrition plan for loss of muscle with aging
This trial studies whether a structured exercise and nutrition program can improve muscle health in older adults with (pre)sarcopenia, especially those who may have slower walking or reduced strength. It also checks safety by excluding people with unstable health problems and several specific medical conditions.
Leuven, Vlaams-BrabantAges 65 years+ - NCT03824106Recruiting
Frailty rehab program for older adults at YMCA
This trial studies a rehabilitation (rehab) program to help older adults who are at risk of losing mobility and independence. You may be offered group-based rehab at the YMCA if you meet age, mobility, safety, and participation requirements.
Hamilton, OntarioAges 65 years+ - NCT03885245RecruitingPhase 2
L-citrulline supplement for overweight adults with later-onset asthma
This Phase 2 trial tests whether adding L-citrulline can improve asthma control in overweight adults whose asthma started later in life. It compares your asthma symptoms and lung testing results to see if the supplement helps when asthma is already being treated.
Durham, North CarolinaAges 18–65 - NCT03908736RecruitingPhase 2
Zinc supplements study for adults on the Navajo Nation
This study tests how daily zinc supplements affect participants in specific Navajo Nation communities by checking changes in blood and urine. It’s mainly meant for adults who are willing to take zinc and come to scheduled study visits.
Albuquerque, New MexicoAges 21–64 - NCT03977207Recruiting
Thyroid hormone supplement for people on dialysis
This trial tests whether taking a thyroid hormone supplement helps people who are on hemodialysis and have borderline-high thyroid lab results (high TSH but normal FT4). It’s studying whether treatment changes thyroid-related outcomes or health while on dialysis.
Orange, CaliforniaAges 18–75 - NCT04041583Recruiting
Cervical spine fusion using spacers to support healing and function
This study looks at how well a specific neck surgery (posterior cervical fusion using added spacers) works for people with long-standing, non-traumatic neck wear-and-tear problems. It will track outcomes using symptoms and imaging to see if the surgery improves function and healing.
Columbus, OhioAges 18 years+ - NCT04096014Recruiting
Protein supplement at night to prevent repeat brain episodes
This study tests whether taking extra protein in the late evening or early morning can lower the chance of being readmitted for hepatic encephalopathy, a brain problem that can happen with liver disease. It may help by supporting safer nutrition and reducing the risk of another hospitalization.
Cleveland, OhioAges 18–75 - NCT04226898RecruitingPhase 2
Synbiotic supplement to lessen schizophrenia symptoms
This Phase 2 trial tests whether a “synbiotic” supplement (a mix of probiotics and prebiotics) can reduce symptoms of schizophrenia or schizoaffective disorder. It may help by targeting gut-related immune and inflammation pathways that could affect brain symptoms.
Batlimore, MarylandAges 18–65 - NCT04275453RecruitingPhase 1/Phase 2
Test diet vs ketone drinks to reach ketosis safely
This early-stage study compares how quickly and effectively a low-carbohydrate diet versus taking ketone supplements helps the heart use less sugar (measured with PET/CT scans). It also looks at how long it takes to reach a “ketosis” state, which may be helpful for metabolic health.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for supplementation?
- Yes. Clin2 currently lists 700 recruiting supplementation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a supplementation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a supplementation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.