Clinical trials
Surgical Site Infection clinical trials
Below are recruiting surgical site infection clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT06363877RecruitingPhase 3
Testing a germ-killing rinse during abdominal surgery
This trial is testing whether a diluted povidone-iodine (a common germ-killer) rinse inside the belly during surgery can prevent infections better than a plain saltwater rinse. It is for adults having abdominal surgery for certain types of wounds.
Loma Linda, CaliforniaAges 18–80 - NCT06378359Recruiting
Preventing staph infections with pre-surgery decolonization
This trial tests if a simple at-home treatment (using a nasal ointment and special body wash) before surgery can prevent staph infections at the surgical site. It's for adults having outpatient surgery in several specialties, like orthopedics or general surgery.
Minneapolis, MinnesotaAges 18 years+ - NCT06312267Enrolling by invitation
Testing a special bandage to prevent wound infections after colon surgery
This trial tests a special bandage that uses a gentle electric charge to help prevent infections in surgical wounds. If you are having planned colon surgery for diverticulitis, polyps, or colon cancer, and you meet certain health requirements, you may be able to join.
Kissimmee, FloridaAges 18–90 - NCT05852158RecruitingPhase 4
Antibiotics to prevent infection after jaw surgery
This trial tests whether giving antibiotics can lower the chance of infection after orthognathic (jaw) surgery. It may help by preventing post-surgery infections, but participation depends on your health history and medication allergies.
Halifax, Nova ScotiaAges 16 years+ - NCT05586776RecruitingPhase 4
Using skin cleaning to prevent post-surgery wound infections
This trial tests a “skin decolonization” routine using medicated skin cleaning to help lower the risk of surgical site infections after abdominal surgery. You may be eligible if you recently had an open abdominal incision and your wound is healing as expected at discharge.
Newport Beach, CaliforniaAges 18 years+ - NCT04725916Recruiting
Study of water exposure and drain-related risks after certain surgeries
This trial looks at how using water (like showers) affects risks related to surgical drains after specific cosmetic or reconstructive procedures. Your results may help improve post-surgery safety guidance for patients who go home with drains.
Danville, PennsylvaniaAges 18 years+ - NCT03561376RecruitingEarly Phase 1
Zinc ointment versus petroleum jelly after skin surgery
This early-phase trial compares zinc oxide ointment versus petroleum jelly to help healing and scar appearance after certain skin surgeries. You might be able to join if you are having a suitable, uninfected, non-scalp skin incision and can use the study ointment.
Pittsburgh, PA, PennsylvaniaAges 18 years+ - NCT07379684RecruitingPhase 1
Amicidin-β for infected surgical or traumatic wounds
This trial tests a topical solution called Amicidin-β for people with infected surgical or traumatic wounds. It may help treat the infection without needing strong oral or IV antibiotics.
Torrance, CaliforniaAges 18–79 - NCT06869096Recruiting
Flushing liquid during colorectal cancer surgery
This trial compares two different liquids used to flush the surgical area during colorectal cancer surgery to see which one better prevents infections. If you are having surgery for colorectal cancer, you may be able to join.
Nanchong, SichuanAges 18–85 - NCT06780813Recruiting
High flow oxygen to reduce infections in obese gynecologic cancer patients
This trial tests whether giving high flow oxygen during and after surgery can lower the risk of infections in obese women with gynecological cancer. It may help improve recovery after surgery.
AthensAges 18–85 - NCT03346694Recruiting
Testing a new chest dressing to prevent wound infections
This trial looks at whether a different dressing placed on the chest incision during certain heart surgeries can lower the risk of surgical wound infections. If you are having a sternotomy (a cut through the breastbone), this could help keep your incision cleaner while you heal.
Stanford, CaliforniaAges 18 years+ - NCT05625373RecruitingPhase 2/Phase 3
Antibiotic powder during groin surgery to prevent infection
This trial studies whether placing an antibiotic powder (vancomycin) directly in the surgical wound during groin lymph node surgery can lower the risk of surgical site infections. It may help reduce wound infections after surgery for vulvar dysplasia.
Providence, Rhode IslandAges 18 years+ - NCT07781878Recruiting
Skin staples vs stitches for planned belly surgery wounds
This trial compares two ways to close the skin after a planned belly operation: using metal staples or traditional stitches. Participation may help doctors learn which method leads to better healing and fewer wound problems.
Islamabad, CapitalAges 15–50 - NCT07735962Recruiting
Drain under skin after gynecologic cancer surgery
This study tests whether placing a small drain under the skin after a deep abdominal incision for gynecologic cancer surgery helps prevent wound problems. It may be a good fit if you have a thicker layer of belly fat and are having a planned surgery.
IstanbulAges 18 years+ - NCT07720154Recruiting
Using hernia sac flap to cover mesh in bony-edged hernia repair
This trial tests whether using a flap of your own hernia sac to cover the mesh during hernia repair can improve healing. It's for people with a complex hernia that touches a bone, like near the breastbone or pelvis.
Minya, Minya GovernorateAges 18–75 - NCT07686913Recruiting
Steri-Strips vs standard closure for C-section incisions
This study compares using Steri-Strips (a special type of tape) to close the C-section incision versus the standard method. The goal is to see which way helps the wound heal better.
Moreno Valley, CaliforniaAges 18 years+ - NCT07620223Recruiting
Antibiotics to prevent infection after liver surgery
This study tests whether giving antibiotics before liver or bile duct surgery can prevent wound infections in areas where bacteria are resistant to many antibiotics. You would receive antibiotics as a preventive measure and be monitored for any surgical site infections.
Nanjing, JiangsuAges 18 years+ - NCT07615517Recruiting
Comparing wound-closure methods for abdominal surgery
This trial compares two ways of closing the layer under your skin after abdominal surgery to see which leads to better healing and fewer complications. You'll be randomly assigned to either have this inner layer stitched or left unstitched.
Augsburg, BavariaAges 18 years+ - NCT07483411Recruiting
Skin glue with stitches vs stitches alone for c-section closure
This trial compares using skin glue plus stitches versus stitches alone to close the skin after a planned c-section. It aims to see if adding glue leads to better healing.
JerusalemAges 18 years+ - NCT06164444Recruiting
Reusable vs disposable drapes and gowns for surgery
This trial compares reusable and single-use surgical drapes and gowns to see which is better for the environment. It includes people having certain types of surgery with at least one incision larger than 5 cm (or 3 cm for children under 16).
GuadalajaraAges 10 years+ - NCT07369700Enrolling by invitation
Mobile health tool for post-C-section checkups in rural Rwanda
This study tests a mobile health tool (used with a community health worker) to improve recovery checkups after a C-section. It may help women in rural areas get better follow-up care.
Kirehe, KireheAges 14 years+ - NCT06858020Recruiting
Hernia prevention after abdominal surgery study
This trial tests if a preventive measure during open abdominal surgery can reduce the chance of developing a hernia later. It is for patients who are having a midline cut that is closed later, not right away, and who are over 18.
HamarAges 18 years+ - NCT06454227Recruiting
Subcutaneous wash during C-sections
This trial tests a new way to clean under the skin after a C-section to reduce the chance of infection. If you are having a C-section, this study may help improve healing.
JerusalemAges Any age
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Common questions
- Are there clinical trials for surgical site infection?
- Yes. Clin2 currently lists 65 recruiting surgical site infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical site infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical site infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.