Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,189 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04451278Recruiting
Brain scan study to predict outcomes after epilepsy surgery in kids
This trial uses resting-state brain MRI (a scan while you’re not doing a task) to help predict how well children with hard-to-treat epilepsy may do after surgery. If you qualify, you would help researchers see whether the scan can forecast prognosis.
Paris, PARISAges 6–18 - NCT04455282Recruiting
Blood test-guided surgery for gastroesophageal cancer
This trial studies blood-based biomarkers to help doctors choose the best individualized surgical treatment for gastroesophageal junction adenocarcinoma. If you qualify, you’ll get standard care plus additional testing to see whether the blood results can guide surgery more precisely.
Cologne, North Rhine-WestphaliaAges 18 years+ - NCT04493996Recruiting
Cognitive training before heart surgery to protect memory
This trial tests whether brain-focused cognitive training before elective heart surgery can help reduce memory and thinking problems afterward. If you qualify, you may do language-based thinking exercises and complete short brain tests around the time of surgery.
Bad NauheimAges 18 years+ - NCT04498221Recruiting
Mapping lymph flow in oropharyngeal cancer with scans
This study uses a special dye or tracer to map how lymph fluid travels from an oropharyngeal (throat) cancer to nearby lymph nodes. It may help doctors understand the most likely spread pattern and plan future treatment more accurately.
LondonAges 18 years+ - NCT04506008RecruitingPhase 2
Radiation followed by surgery for soft tissue sarcoma
This trial tests a treatment plan where you first get a shorter (hypofractionated) course of radiation and then have surgery to remove the tumor. It may help control the cancer locally in certain soft tissue sarcomas and improve surgical outcomes.
Nashville, TennesseeAges 18 years+ - NCT04515459RecruitingPhase 2
Pre-surgery exercise and care program for limb sarcoma
This Phase 2 trial tests a “prehabilitation” program done before surgery to help people with arm or leg (limb) sarcoma be better prepared for their operation. It may help improve how well patients tolerate treatment and recover by planning supportive care around the weeks before surgery.
ToulouseAges 16 years+ - NCT04527705Recruiting
Testing endodontic retreatment in one versus two visits
This study compares doing tooth root-canal retreatment in one visit versus two visits. It’s meant to see which approach leads to better outcomes for teeth with infection at the root tip (apical periodontitis).
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT04552145Recruiting
Physical therapy versus surgery for lumbar spinal stenosis
This study compares physical therapy to surgery to help relieve symptoms from narrowing in the lower spine. It looks at which treatment works best for walking discomfort caused by spinal stenosis.
LillehammerAges 50–80 - NCT04570553Recruiting
Testing a tool during surgery for early endometrial cancer
This study looks at how well a surgical tool is used during standard surgery for early endometrial cancer, and whether it relates to test results from fluid taken in the abdomen. It may help surgeons improve how samples are collected and interpreted during routine care.
York, PennsylvaniaAges 18 years+ - NCT04578301Recruiting
Predicting who develops serious liver worsening after surgery
This study looks at your liver health before and after surgery to predict the risk of “acute-on-chronic liver failure,” which means a sudden worsening of liver function on top of an existing liver condition. If you qualify, your doctors may use study data to better identify who needs closer monitoring after surgery.
BonnAges 18 years+ - NCT04606030Recruiting
Tested lymph surgery for breast-cancer–related arm swelling
This trial studies a specialized lymph surgery (called VLNT, moving lymph tissue) to treat swelling in an arm caused by breast cancer treatment. It may help reduce lymphedema that doesn’t fully improve with compression and elevation.
Chicago, IllinoisAges 18–75 - NCT04623502Recruiting
Study of kidney and bladder cancer metabolism during surgery
This study looks at how kidney and bladder (urothelial) tumors use fuel by taking samples during surgery or biopsy. It may help researchers learn what drives these cancers and guide better future treatments.
Dallas, TexasAges 18 years+ - NCT04635657Recruiting
Testing brain function after meningioma surgery
This study measures how thinking and memory change after surgery to remove a meningioma near the front or side of the brain. It may help doctors better understand what to expect and how cognitive recovery can differ from person to person.
Columbus, OhioAges 18–89 - NCT04638790RecruitingPhase 3
First treatment chemotherapy study for newly diagnosed Hodgkin lymphoma
This trial studies the best first chemotherapy approach for people newly diagnosed with classical Hodgkin lymphoma. It may help improve outcomes by comparing how treatment is given in routine care settings in Russia.
Mumbai, Opd-81 Main Building, Dr. E Borges Road, Parel 400012Ages 18–50 - NCT04655404RecruitingEarly Phase 1
Larotrectinib for children with newly diagnosed glioma with NTRK fusion
This trial tests larotrectinib, a targeted cancer medicine, in children and teens with newly diagnosed high-grade brain glioma that has an NTRK fusion. It may help shrink or control tumors by targeting a specific genetic change in the cancer.
Aurora, ColoradoAges Up to 21 years - NCT04666961RecruitingPhase 2
Hormone therapy before surgery for extensive DCIS
This Phase 2 study tests whether taking hormone medicine before surgery can change the surgical plan and outcomes for people with extensive ductal carcinoma in situ (DCIS). It is for estrogen-receptor positive DCIS and aims to see how this “neoadjuvant” approach affects treatment decisions.
AngersAges 40 years+ - NCT04671771Recruiting
Testing a new graft for hemodialysis access in kidney failure
This study tests whether an “AV graft” implant works safely and well for people with end-stage kidney disease who need hemodialysis. It may help your dialysis access last and work better, compared with current expectations for AV grafts.
Phoenix, ArizonaAges 18–90 - NCT04687956Recruiting
Preventing arm swelling after breast cancer lymph node surgery
This study looks at ways to prevent arm swelling (lymphedema) related to breast cancer after surgery to remove lymph nodes. It may help people who are getting axillary lymph node dissection lower the chance of long-term swelling.
SeoulAges 19 years+ - NCT04708808Recruiting
Music therapy during ultrasound-guided abortion procedure
This trial tests whether listening to music during an ultrasound-guided vacuum aspiration procedure can help make the procedure more comfortable or less stressful. It focuses on people having first-trimester pregnancy termination under local anesthesia.
Hong Kong, ShatinAges 18 years+ - NCT04715425Recruiting
Surgery vs catheter procedure for persistent atrial fibrillation
This trial compares two ways to treat persistent atrial fibrillation: a minimally invasive surgery approach versus a catheter ablation. It may help people find the most effective option to reduce ongoing abnormal heart rhythm and avoid repeat procedures.
AmsterdamAges 18–80 - NCT04725916Recruiting
Study of water exposure and drain-related risks after certain surgeries
This trial looks at how using water (like showers) affects risks related to surgical drains after specific cosmetic or reconstructive procedures. Your results may help improve post-surgery safety guidance for patients who go home with drains.
Danville, PennsylvaniaAges 18 years+ - NCT04743765Recruiting
Faster hip fracture care for people with heart stress signs
This study looks at an “accelerated” hospital plan to get surgery and treatment started sooner for some people with a hip fracture who also show signs of heart stress in blood tests. It may help reduce delays and improve safety during urgent hip fracture care.
Chandler, ArizonaAges 45 years+ - NCT04785976Recruiting
Study of long-term outcomes after a ruptured brain aneurysm bleed
This trial is a long-term follow-up study of people who come to the emergency room with a ruptured brain aneurysm (bleeding in the space around the brain). It helps doctors understand what outcomes are most common and what may affect recovery over time.
Beijing, Beijing MunicipalityAges Any age - NCT04807140RecruitingPhase 2
Study of toripalimab before surgery for head and neck cancer
This trial tests toripalimab (an immunotherapy) given before surgery for untreated head and neck squamous cell carcinoma, either alone or with chemotherapy. The goal is to shrink or control the cancer earlier and see if it improves outcomes for people who plan curative surgery.
Guangzhou, GuangdongAges 18–80
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,189 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.