Clinical trials · Florida
Total Knee Arthroplasty clinical trials in Florida
We’re tracking 11 recruiting total knee arthroplasty studies with a site in Florida — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT07107581Enrolling by invitation
Exactech knee replacement follow-up study
This study is following patients who have or will receive an Exactech total knee replacement. It looks at how well the knee works over time and helps doctors understand long-term results.
DeLand, FloridaAges 18 years+ - NCT05653102Recruiting
Collecting data on a knee replacement system after surgery
This study collects real-world health and surgery records to better understand how the Truliant total knee replacement performs. It may help doctors and patients by improving future guidance on this knee system’s safety and effectiveness.
DeLand, FloridaAges 18 years+ - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT06040827Recruiting
Study of a knee implant extension for knee replacement
This trial is for adults having their first knee replacement surgery. It tests a special part (tibial extension) of a common knee implant system. Researchers will follow participants over time to see how well it works.
Tampa, FloridaAges 18 years+ - NCT07437469Recruiting
Binaural beats for pain and anxiety after surgery
This trial tests if listening to binaural beats (a type of sound therapy) after hip or knee replacement surgery can help reduce pain and anxiety. You would receive the sound therapy through headphones while in the recovery room.
Miami, FloridaAges 18–99 - NCT07213778RecruitingPhase 3
Comparing a new drug to aspirin for blood clot prevention after knee replacement
This trial tests a new medicine called REGN7508 against aspirin to prevent blood clots after total knee replacement surgery. It may help if you are having a planned knee replacement and are in good health.
Deerfield Beach, FloridaAges 18 years+ - NCT07015905RecruitingPhase 3
Study of REGN7508 vs. standard blood thinners after knee replacement
This trial compares a new blood thinner called REGN7508 to two standard blood thinners (apixaban and enoxaparin) to prevent blood clots after total knee replacement surgery. The goal is to see which is safer and more effective.
Delray Beach, FloridaAges 18 years+ - NCT05792189Recruiting
Knee fracture surgery: plates vs knee replacement for older adults
This trial compares two ways to treat certain lower-thigh (distal femur) fractures near the knee: using plates/screws or doing a knee replacement. It aims to see which option works better for recovery and long-term outcomes.
Gainesville, FloridaAges 55–100 - NCT06747494Recruiting
Comparing general vs spinal anesthesia for hip or knee replacement
This study compares two types of anesthesia (general and spinal) for people having a total hip or knee replacement. The goal is to see which approach is better for recovery and overall outcomes.
Miami, FloridaAges 18 years+ - NCT04295486RecruitingPhase 2
Low-dose aspirin to prevent blood clots after hip or knee surgery
This Phase 2 study tests the best dose of low-dose aspirin to help prevent dangerous blood clots after total hip or knee replacement surgery. If you’re at lower clot risk and can safely take aspirin, it may help reduce clot risk while you recover.
Miami, FloridaAges 19 years+ - NCT06902285RecruitingPhase 4
Magnesium supplement for better sleep after joint replacement
This study tests whether taking magnesium L-threonate can improve sleep quality after total knee or hip replacement surgery. It may help you sleep better during recovery.
Miami, FloridaAges 18 years+
Where these studies are running in Florida
Institutions with a site for the recruiting total knee arthroplasty studies listed above.
- University of Miami · 5 studies
- Phoenix Clinical Research · 2 studies
- Ascension Sacred Heart Hospital
- Bioresearch Partner
- Delray Physician Care Center
- Florida Orthopaedic Associates
- Florida Research Associates
- Foundation for Orthopaedic Research and Education
What taking part in a total knee arthroplasty study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Total Knee Arthroplasty trials in other states
Common questions
- Are there total knee arthroplasty clinical trials in Florida?
- Yes. We're currently tracking 11 recruiting total knee arthroplasty studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a total knee arthroplasty study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a total knee arthroplasty trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New total knee arthroplasty studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.