Clinical trials
Upper Gastrointestinal Disorder clinical trials
Below are recruiting upper gastrointestinal disorder clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05132816Recruiting
Test manometry after partial anti-reflux surgery
This study checks how well a swallowing test called high-resolution manometry works after partial anti-reflux surgery. It focuses on adults with certain abnormal esophagus muscle patterns to help doctors understand what to expect after the operation.
Schlieren, Canton of ZurichAges 18 years+ - NCT07727226Recruiting
Patient views on single-use gastroscopes
This study asks patients like you to share their experience about using a single-use gastroscope during an elective or subacute upper endoscopy. Your feedback will help doctors understand how these disposable scopes work in everyday practice.
KøgeAges 18 years+ - NCT06581016Recruiting
Single-use vs. reusable scopes for stomach exams in the OR
This study compares single-use and reusable gastroscopes to see which works better during stomach exams done in the operating room. It may help you understand the tools used in your procedure.
KøgeAges 18 years+ - NCT06771102Recruiting
New single-use gastroscope compared to standard for bedside use
This trial tests a single-use gastroscope used at the bedside versus the standard reusable gastroscope used in the endoscopy unit. It aims to see if the bedside scope works as well for patients who are already in the hospital and need an upper endoscopy without general anesthesia.
KøgeAges 18 years+ - NCT06697691Recruiting
Predicting rebleeding risk after upper gut bleeding
This study aims to create a tool that helps doctors predict if a patient with upper gut bleeding (not from veins) will rebleed while still in the hospital. It uses information from your hospital stay to better understand your risk and improve care.
Wuhan, HubeiAges 18 years+ - NCT05812339Enrolling by invitation
Mapping tests for stomach symptoms using body-surface sensors
This study checks whether a noninvasive “mapping” test placed on the belly and chest can help tell apart people with certain upper stomach symptoms from healthy controls. It may help researchers better understand stomach function and symptoms without relying only on invasive tests.
Calgary, AlbertaAges 18 years+ - NCT06951490Enrolling by invitation
PillSense study for anemia and blood in stool
This trial tests a special pill that can be swallowed to help find the cause of anemia or hidden blood in the stool, without the need for more invasive tests. It is for patients who are already in the hospital and have been referred to a gastroenterologist.
Orlando, FloridaAges 18 years+ - NCT01696734RecruitingPhase 3
Domperidone for difficult stomach and reflux problems
This trial studies whether domperidone can help people whose stomach or reflux symptoms did not improve with usual treatments. It focuses on symptoms like slow stomach emptying, hard-to-control acid reflux, or severe indigestion.
Houston, TexasAges 16 years+ - NCT05846802Recruiting
Gastroparesis and stomach symptoms registry for adults
This registry is for adults with long-lasting stomach emptying problems or related symptoms, helping researchers better understand patterns of nausea, pain, and fullness. You may be able to join if you meet specific symptom and test results, and can complete a stomach-emptying scan.
Scottsdale, ArizonaAges 18–85 - NCT07755384Recruiting
Stomach and throat exam study at high altitude
This study looks at what doctors see in the upper digestive tract (stomach and food pipe) of people living at high altitude, using a sedated endoscopy (a camera tube down the throat while you sleep). It helps understand how high altitude affects the digestive system.
Yushu, QinghaiAges 18 years+ - NCT06338683RecruitingPhase 3
Olanzapine for advanced upper digestive and lung cancer survival
This study tests whether a medicine called olanzapine can improve survival in people with advanced cancers of the upper digestive system or lungs. Olanzapine may help with appetite and weight, which are common problems in these cancers.
Xining, QinghaiAges 18–80 - NCT06846359Recruiting
Hypnotherapy for Upper Gut Symptoms
This study tests whether hypnotherapy sessions, delivered through a smartphone app, can help relieve upper digestive symptoms like nausea, bloating, and indigestion. It's for people whose symptoms are not caused by a known disease and who have already had normal stomach-emptying tests.
Rochester, MinnesotaAges 18 years+ - NCT03596476Recruiting
Test for reflux causes after proton pump pills fail
This study checks whether a special test of the esophagus after meals can find the exact reason for ongoing reflux symptoms when proton pump pills (PPIs) don’t help. It may help doctors choose the right next treatment for people whose reflux symptoms keep coming back.
Chambray-lès-ToursAges 18 years+ - NCT05212129Recruiting
Stimulation of the ear nerve to help gut symptoms
This study tests whether stimulating a nerve in the ear (called auricular vagal nerve stimulation) can improve upper gut symptoms in teens who may have hypermobile Ehlers-Danlos syndrome (hEDS) or hypermobile spectrum disorder (HSD). It also checks whether this treatment helps nerves that control the body (autonomic nervous system) and how well the gut moves.
Milwaukee, WisconsinAges 10–18 - NCT05832528Recruiting
Low FODMAP diet for indigestion after meals
This study tests whether a low FODMAP diet can reduce symptoms of functional indigestion or post-meal discomfort. It’s mainly for people whose symptoms are clearly linked to eating and who haven’t changed diets recently.
Leuven, Vlaams-BrabantAges 18–70 - NCT06500468Recruiting
A capsule test for suspected upper GI bleeding
This trial tests a new ingestible capsule called PillSense that can detect bleeding in the upper part of your digestive system. If you come to the emergency room with signs of upper GI bleeding (like vomiting coffee-ground material or having black stools) but without obvious black stool on a physical exam, this study will see if the capsule works as well as the usual endoscopy procedure.
SingaporeAges 21–99 - NCT06904872RecruitingPhase 2
Testing a diarrhea drug for short bowel syndrome without a colon
This trial tests if crofelemer can reduce diarrhea and fluid loss in people with short bowel syndrome who have a stoma (no colon connection) and need intravenous nutrition or fluids. The goal is to see if it improves gut function and quality of life.
AachenAges 18 years+ - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT06716658RecruitingPhase 2
New targeted drug for certain T/NK-cell lymphomas
This trial tests an oral JAK1 inhibitor called golidocitnib for people with T/NK-cell lymphoma that came back after treatment or didn't respond. The drug works by blocking a signal that helps cancer cells grow.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07381374Recruiting
Fecal transplant for children with autism
This trial tests whether fecal microbiota transplantation can help children with moderate-to-severe autism. It involves giving healthy donor bacteria to improve gut health and possibly autism symptoms.
Shenzhen, GuangdongAges 3–16 - NCT05924555Recruiting
Exercise testing in inherited fatty acid breakdown disorders
This study checks how well people with long-chain fatty acid breakdown disorders tolerate exercise. It may help doctors better understand exercise limits and how to manage symptoms during activity.
Amsterdam, North HollandAges 18 years+
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Common questions
- Are there clinical trials for upper gastrointestinal disorder?
- Yes. Clin2 currently lists 21 recruiting upper gastrointestinal disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a upper gastrointestinal disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a upper gastrointestinal disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.