Clinical trials
Venous Insufficiency clinical trials
Below are recruiting venous insufficiency clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07362719Recruiting
Thermal cure for severe leg vein problems
This study tests if a 3-week thermal spa treatment can improve symptoms of severe chronic venous insufficiency (vein problems in your legs that cause swelling, skin changes, and risk of leg ulcers). It may help if you have serious vein issues but no open ulcers.
AmnévilleAges 18 years+ - NCT07603076Recruiting
Vein Problems and Symptoms in Lipedema
This study looks at how vein function relates to lipedema (a condition causing painful fat buildup in legs). Researchers will use ultrasound to check your veins and ask about your symptoms to better understand how the two conditions connect.
Istanbul, UskudarAges 18–65 - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT07777978Recruiting
Home exercise and education for chronic venous insufficiency
This study tests a structured home-based exercise and education program for people with chronic venous insufficiency – a condition where veins in the legs have trouble sending blood back to the heart. If you qualify, you would do the program for 12 weeks to see if it helps improve your symptoms.
Bolu, BoluAges 18 years+ - NCT04253301Recruiting
Testing a vein valve device for chronic venous valve leak
This study tests whether an implanted “vein valve” system can improve blood flow in people with painful chronic venous valve leakage in the thigh/knee veins. It also checks if the procedure and follow-up are safe and workable, especially with blood-thinner medicines before and after.
Nedlands, Western AustraliaAges 18 years+ - NCT06228365Recruiting
Minimally invasive vein surgery with sedation
This trial tests a new way to perform minimally invasive surgery for superficial venous insufficiency (a common vein problem) using sedation and local anesthesia. It aims to see if using a virtual reality headset during the procedure helps patients feel more comfortable.
Saint-JeanAges 18 years+ - NCT07233616Recruiting
Radiofrequency ablation for chronic venous insufficiency in patients 80+
This study tests whether a procedure called radiofrequency ablation (using heat to close faulty veins) is safe and effective for people aged 80+ with chronic venous insufficiency. It aims to relieve symptoms like leg swelling, skin changes, or ulcers.
Chengdu, SichuanAges 80 years+ - NCT06350695Recruiting
Compression stockings for heart failure with leg swelling
This trial tests whether wearing compression stockings can help people with heart failure who have leg swelling. Researchers want to see if stockings reduce fluid buildup and improve daily life.
Dallas, TexasAges 18 years+ - NCT07737236Recruiting
Ruscus study for symptom relief in chronic vein problems
This study tests a natural plant extract called Ruscus to see if it helps control symptoms of chronic venous insufficiency, a condition where leg veins have trouble moving blood back to the heart. It is for people who are already starting this treatment as part of their regular care.
Ankara, AnkaraAges 18–75 - NCT06707090RecruitingPhase 3
Tissue repair gel for venous leg ulcers
This trial tests a gel that helps heal leg ulcers caused by poor blood flow in the veins. It may help if you have a venous leg ulcer that has not healed on its own after at least 4 weeks.
Tucson, ArizonaAges 18 years+ - NCT06707103RecruitingPhase 3
Gel treatment for venous leg ulcers
This trial tests whether a special gel helps heal venous leg ulcers faster. It is for people with a diagnosed vein problem and a leg ulcer between 2 and 12 square centimeters that has been present for at least 4 weeks.
Jacksonville, FloridaAges 18 years+ - NCT07478406Enrolling by invitation
Pelvic floor and vein health connection study
This study looks at how pelvic floor muscles relate to leg vein problems (venous insufficiency). You may benefit if you have vein issues and are willing to try telerehabilitation.
Istanbul, IstanbulAges 30–65 - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT06418282Recruiting
Portable compression device for leg swelling
This study tests a new portable device that wraps around your leg to gently squeeze and reduce swelling from lymphedema or vein problems. It aims to see if at-home use can improve symptoms and lower healthcare costs compared to standard care.
New York, New YorkAges 18–100 - NCT06693245Recruiting
Pain during microwave treatment for varicose veins
This study looks at how much pain people feel during a microwave treatment for varicose veins in the leg. It aims to understand what factors affect pain, so the treatment can be more comfortable for future patients.
Chengdu, SichuanAges 18–90 - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT07449728Recruiting
Laser treatment for varicose veins with different wavelengths
This trial tests different types of laser energy to treat varicose veins. It looks at which wavelength works best for closing the faulty vein and preventing the disease from getting worse.
MoscowAges 18 years+ - NCT07624929Enrolling by invitation
Virtual Reality to Reduce Anxiety During Varicose Vein Treatment
This study tests whether wearing a virtual reality headset during varicose vein treatment (a minimally invasive laser procedure on your legs) can help reduce anxiety and pain. You'd use VR while the doctor treats the problematic veins under local anesthesia.
BydgoszczAges 18 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Birmingham, AlabamaAges Any age
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Common questions
- Are there clinical trials for venous insufficiency?
- Yes. Clin2 currently lists 19 recruiting venous insufficiency studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a venous insufficiency trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a venous insufficiency trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.