Clinical trials
Venous Insufficiency of Leg clinical trials
Below are recruiting venous insufficiency of leg clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07362719Recruiting
Thermal cure for severe leg vein problems
This study tests if a 3-week thermal spa treatment can improve symptoms of severe chronic venous insufficiency (vein problems in your legs that cause swelling, skin changes, and risk of leg ulcers). It may help if you have serious vein issues but no open ulcers.
AmnévilleAges 18 years+ - NCT06350695Recruiting
Compression stockings for heart failure with leg swelling
This trial tests whether wearing compression stockings can help people with heart failure who have leg swelling. Researchers want to see if stockings reduce fluid buildup and improve daily life.
Dallas, TexasAges 18 years+ - NCT06693570RecruitingPhase 4
Fish skin graft for hard-to-heal leg ulcers
This trial tests whether applying a special fish skin graft, along with standard compression therapy, helps heal leg ulcers caused by poor vein function (venous leg ulcers) that have not healed with standard care alone. If you have a nonhealing venous leg ulcer, this study may offer a new treatment option.
Monroeville, PennsylvaniaAges 18 years+ - NCT06707090RecruitingPhase 3
Tissue repair gel for venous leg ulcers
This trial tests a gel that helps heal leg ulcers caused by poor blood flow in the veins. It may help if you have a venous leg ulcer that has not healed on its own after at least 4 weeks.
Tucson, ArizonaAges 18 years+ - NCT06707103RecruitingPhase 3
Gel treatment for venous leg ulcers
This trial tests whether a special gel helps heal venous leg ulcers faster. It is for people with a diagnosed vein problem and a leg ulcer between 2 and 12 square centimeters that has been present for at least 4 weeks.
Jacksonville, FloridaAges 18 years+ - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT07061613Recruiting
Study of NeoThelium FT for venous leg ulcers
This trial tests a new wound dressing called NeoThelium FT for healing venous leg ulcers. It looks at how safe and effective it is.
Metairie, LouisianaAges 18 years+ - NCT07211243Recruiting
Comparing two dressings for infected leg ulcers
This trial tests if a new version of a special dressing (Suprasorb X+PHMB Pro) works better than the current version for treating infected venous leg ulcers. It may help people with mildly to moderately draining wounds that are infected.
BialystokAges 18 years+ - NCT07335861Recruiting
Hyalomatrix for healing venous leg ulcers
This trial tests a special gel-like dressing (Hyalomatrix) to see if it helps heal leg ulcers caused by poor blood flow in the veins. It may be a good option if you have a chronic venous leg ulcer that hasn't healed much despite standard care.
Alexandria, LouisianaAges 18 years+ - NCT06693245Recruiting
Pain during microwave treatment for varicose veins
This study looks at how much pain people feel during a microwave treatment for varicose veins in the leg. It aims to understand what factors affect pain, so the treatment can be more comfortable for future patients.
Chengdu, SichuanAges 18–90 - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT03716167Recruiting
Near-infrared laser for healing and pain in leg vein ulcers
This study tests whether a near-infrared laser can improve healing and reduce pain in chronic venous leg ulcers. If you qualify, you may receive laser treatment and will be checked over time for wound healing and pain levels.
Winston-Salem, North CarolinaAges 18 years+ - NCT04737941Recruiting
Study of treatment for leg ulcers from weak leg veins
This study looks at people with a healing or healing-worsening leg ulcer caused by weak veins (venous reflux). It may help improve care for this common type of ulcer and reduce time to healing by testing an approach for venous ulcers.
HelsinkiAges 18 years+ - NCT07048054RecruitingPhase 1/Phase 2
Patch of fat cells for chronic leg ulcers
This trial tests a patch made from your own fat cells (called TrophiPatch) to see if it helps heal chronic leg ulcers. It is for people with venous leg ulcers or diabetic foot ulcers that are not healing well with standard care.
GenevaAges 18 years+ - NCT06568627RecruitingPhase 3
Testing a gel for cleaning leg ulcers
This study tests a new gel that helps remove dead tissue from venous leg ulcers. Venous leg ulcers are open sores on the leg that happen when veins don't work well. The gel is applied to the ulcer to clean it and help it heal. You may be able to join if you are an adult with a venous leg ulcer that is not too large and has been there for a few weeks.
Phoenix, ArizonaAges 18 years+ - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT07541196Recruiting
PAW-Hydrogel treatment for long-lasting wound healing
This study tests a special gel called PAW-Hydrogel to help heal chronic wounds (wounds that have not closed after 3+ months). The gel may help wounds close faster by supporting the natural healing process.
Ocoyoacac, State of MexicoAges 18 years+
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Common questions
- Are there clinical trials for venous insufficiency of leg?
- Yes. Clin2 currently lists 17 recruiting venous insufficiency of leg studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a venous insufficiency of leg trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a venous insufficiency of leg trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.