Clinical trials
Ventilation clinical trials
Below are recruiting ventilation clinical trials, each written for real people, not researchers. We’re tracking 529 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06985225Recruiting
Study of mucus plugs and lung function in mucus-related lung disease
This study looks at how mucus plugs affect air flow in the lungs. It may help find new ways to treat people with lung conditions like cystic fibrosis, severe asthma, COPD, or bronchiectasis.
Kansas City, KansasAges 18–65 - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT02464696Recruiting
Noninvasive breathing support to avoid tube breathing in cancer
This trial studies a mask-based breathing treatment (noninvasive ventilation) for people with cancer and serious breathing trouble, to see if it can prevent the need for intubation (putting a breathing tube in). If you qualify, the goal is to help you breathe better without invasive airway support when possible.
Houston, TexasAges 18 years+ - NCT02919930Recruiting
Testing a new breathing support choice for central sleep apnea
This study looks at which settings to use for adaptive servo-ventilation (ASV), a machine that helps breathing during sleep. It is meant for people with central sleep apnea who are not getting enough benefit from CPAP, so ASV may be a better match.
LeuvenAges 18 years+ - NCT07262541Recruiting
Measuring airway opening pressure in children on ventilators
This study tests a simple way to measure the pressure needed to open the airways in children on a breathing machine. It may help doctors provide better breathing support for your child in the intensive care unit.
ParisAges Up to 17 years - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07426458RecruitingPhase 4
Breathing and blood flow study for adults with asthma
This study looks at how asthma affects air flow and blood flow in your lungs. You may join if you use daily asthma control medicine and your breathing test shows room for improvement even after using a rescue inhaler.
Miami, FloridaAges 18–75 - NCT07430124Recruiting
Two breathing methods during balloon dilation for airway procedure
This study compares two ways of delivering breaths during a balloon dilation procedure to see which works better and is safer for your lungs.
AnkaraAges 18–65 - NCT07451405Recruiting
Using OLE therapy for lung expansion in ventilated patients with collapsed lungs
This trial tests a breathing treatment called Oscillation and Lung Expansion (OLE) therapy. It is for people on a breathing machine who have a collapsed area in the lung (atelectasis) and a lot of phlegm. The goal is to help open the lungs and clear mucus more easily.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07467187Recruiting
Home Ventilation with Tracheostomy in Denmark (2016–2025)
This study looks at people in Denmark who need a home ventilator through a tracheostomy. It aims to understand their care and outcomes over several years.
CopenhagenAges Any age - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT07503509Recruiting
Study of high PEEP in noninvasive ventilation
This study tests whether using higher pressure settings (PEEP) on a noninvasive breathing mask can help people with low oxygen levels. The doctors will measure the pressure inside your esophagus to guide the treatment.
Chongqing, Chongqing MunicipalityAges 18–100 - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07578545Recruiting
Pain management after minimally invasive chest surgery
This study tests whether combining a specific type of chest surgery (using small cameras) with numbing injections around nerves reduces pain and the need for strong pain medications after surgery. Researchers want to see if this approach helps patients recover better with less opioid use.
Antalya, MuratpaşaAges 18–75 - NCT07590362Recruiting
Testing breathing readiness measures in ventilated COPD patients
This study compares two methods of measuring whether patients with COPD who are on breathing machines are ready to breathe on their own. The goal is to find the best way to predict which patients can successfully come off the ventilator.
Sohag, Sohag GovernorateAges 18 years+ - NCT07613021Recruiting
Breathing Muscle Training to Help ICU Patients Stop Using Ventilators
This trial tests whether special breathing exercises can help patients who have been on a breathing machine (ventilator) in the ICU for at least 3 days get off the machine more successfully. The exercises focus on strengthening the muscles you use to breathe in.
ChalcisAges 18 years+ - NCT07653568Recruiting
Comparing two ultrasound methods to guide fluid therapy in septic patients on ventilators
This study tests whether a neck ultrasound (carotid Doppler) or a heart ultrasound (echocardiography) is better at determining how much fluid a septic patient on a ventilator needs. If you or your loved one is in the ICU with sepsis on a breathing machine, this trial helps doctors choose the best way to give fluids that can improve blood pressure and organ function.
Islamabad, Federal AreaAges 12 years+ - NCT07235345Enrolling by invitation
Lung medication with different oxygen levels for premature babies
This study tests a lung medication called pulmonary surfactant, given with different oxygen levels, to help very premature babies (born before 32 weeks) who have breathing difficulties. The goal is to see which oxygen level works best with non-invasive breathing support.
Henan, ZhengzhouAges 6 months–7 months - NCT07164781Enrolling by invitation
Probiotics for preventing infections in ICU patients
This trial tests whether probiotics (good bacteria) can help prevent serious infections in critically ill patients in the ICU. If you are very sick and in the ICU, you may be able to join — as long as you don't have certain conditions like cancer or a weakened immune system.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT07110428Enrolling by invitation
Breathing support during hysteroscopy surgery
This trial studies a special way to deliver oxygen during hysteroscopy surgery, using a tube placed above the vocal cords (supraglottic jet oxygenation). It may offer a safer and more comfortable breathing option during the procedure.
Guangdong, ShenzhenAges 18–65 - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06624254Enrolling by invitation
Breathing machine settings for lung recovery in ICU
This study looks at how a specific type of breathing machine setting (adaptive pressure control) affects your lungs and recovery. It aims to find the best way to support breathing for people in the ICU with respiratory failure.
La Jolla, CaliforniaAges 18 years+ - NCT05462600Enrolling by invitation
Breathing monitoring test in non-smokers
This study measures how you breathe and how well oxygen and carbon dioxide move in and out of your lungs. It’s mainly a monitoring study to help researchers understand breathing patterns during a breathing test.
La Jolla, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for ventilation?
- Yes. Clin2 currently lists 529 recruiting ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.