Clinical trials
Prolonged Mechanical Ventilation clinical trials
Below are recruiting prolonged mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06368089Recruiting
Breathing muscle training for patients on a ventilator
This study tests two types of breathing exercises for people who have been on a breathing machine (ventilator) for more than 48 hours and are ready to start breathing on their own. The goal is to see which exercise helps them get off the ventilator faster.
SongkhlaAges 40–80 - NCT07445035Recruiting
Robotic leg brace to help walking while on a breathing machine
This study tests whether walking with a robotic leg brace (exoskeleton) can help people who are on a breathing machine get better faster. It is for adults in the intensive care unit who can sit, stand with help, and have no major leg or heart problems.
New Taipei CityAges 45–65 - NCT06520605Recruiting
CMV reactivation in ICU patients on ventilators for a week or more
This study looks at whether a common virus called cytomegalovirus (CMV) becomes active again in ICU patients who need a breathing machine for a week or more. It may help doctors understand who is at risk and how to better care for them.
Lucknow, Uttar PradeshAges 18–80 - NCT06125210Recruiting
Early treatment bundle to prevent ventilator dependence in kids
This study tests a set of early therapies (a 'bundle') for children on breathing machines to help them get off the machine sooner and avoid long-term dependence. It may be a good fit if your child is stable and doesn't have severe brain or spine problems.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT07177183Recruiting
Low creatinine as a sign of longer breathing tube use
This study looks at whether low blood creatinine levels can help predict which patients will need a breathing machine for a long time or have trouble coming off it. If you are under 18 and in a post-ICU care unit, you may be able to join.
BrnoAges 18 years+ - NCT05634135Recruiting
Testing breathing and blood-flow patterns in long-term ventilated ICU patients
This study looks at how well air moves through the lungs and how blood flows in different types of patients who have been on a breathing machine for a long time. It may help clinicians better understand these patterns during “weaning” (trying to come off the machine), which could improve care plans.
TaipeiAges 20 years+ - NCT07372794Recruiting
Lung imaging-guided breathing therapy for patients on ventilators for weeks
This study tests whether using a special lung imaging technique called EIT can help guide breathing exercises and physical therapy for people who have been on a breathing machine for 21 days or more. The goal is to see if this approach helps your lungs work better and speeds up recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07002710Recruiting
Long-term ventilation and inflammation study
This study looks at how long-term inflammation affects the breathing of people who have been on a ventilator for 10 days or more. It aims to help doctors better understand and support your recovery.
TaipeiAges 20 years+ - NCT07003672Recruiting
Weaning from ventilator: a lung measurement study
This study looks at people who have a tracheostomy and have been on a breathing machine for at least two weeks. Researchers want to see if certain lung measurements can help predict how easy or hard it will be to come off the ventilator.
TaipeiAges 20 years+ - NCT07451405Recruiting
Using OLE therapy for lung expansion in ventilated patients with collapsed lungs
This trial tests a breathing treatment called Oscillation and Lung Expansion (OLE) therapy. It is for people on a breathing machine who have a collapsed area in the lung (atelectasis) and a lot of phlegm. The goal is to help open the lungs and clear mucus more easily.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT06719258Recruiting
Trial on heated humidifiers for breathing tubes
This trial studies how heating and adding moisture to the air breathed through a breathing tube (called a heated humidifier) affects patients in intensive care. It focuses on people who need the breathing tube for a longer time or special protective settings.
Québec, QuebecAges 18 years+ - NCT05188092Recruiting
Lung ultrasound to guide fluid removal in ICU patients
This trial tests whether using a quick scan of the lungs (lung ultrasound) helps ICU teams safely remove the right amount of extra body fluid. It aims to improve care for people who have just been put on a breathing machine but are expected to need it longer than a day.
Arnhem, GelderlandAges 18 years+ - NCT07774065Recruiting
Ventilation strategies in obese patients during laparoscopic surgery
This study tests different ways of using a breathing machine (ventilator) during laparoscopic surgery in people with obesity. The goal is to find a safer and more effective ventilation method for this group.
Galveston, TexasAges 18 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT06009731Recruiting
Diaphragm ultrasound during breathing trial
This study uses a special ultrasound technique to look at how your diaphragm (the main breathing muscle) moves while you try breathing on your own. It may help doctors better understand when patients are ready to come off the breathing machine.
AmiensAges 18 years+ - NCT06694740RecruitingPhase 2/Phase 3
Interferon gamma for immune recovery in the ICU
This trial tests if a drug called interferon gamma can help boost the immune system of patients in the ICU who are fighting serious infections. It is for adults who are on a breathing machine and have low immune function.
ParisAges 18 years+ - NCT06410664Recruiting
Longer use of heat-moisture exchangers in the ICU
This study tests if keeping a device called a heat and moisture exchanger (HME) on a breathing tube for longer periods is safe and effective for ICU patients who need breathing support. It aims to reduce infections and complications.
Prague, Česká RepublikaAges 18 years+
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Common questions
- Are there clinical trials for prolonged mechanical ventilation?
- Yes. Clin2 currently lists 20 recruiting prolonged mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prolonged mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prolonged mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.