Clinical trials
Ventilation clinical trials
Below are recruiting ventilation clinical trials, each written for real people, not researchers. We’re tracking 506 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05767671Recruiting
Breathing tube patients in ICU tested for lung inflammation treatment
This trial studies whether changing immune cells in the lungs (using a procedure called MiniBAL) can improve outcomes in adults who are critically ill and on a breathing tube. It may help doctors better manage acute lung injury by targeting inflammation early in the ICU stay.
Denver, ColoradoAges 18–99 - NCT05741697Recruiting
High-flow oxygen for bronchiectasis flare-ups in intensive care
This trial tests high-flow oxygen (a special oxygen delivery through a device) for people hospitalized with a bronchiectasis flare-up who need breathing support. It may help people avoid more invasive breathing machines and improve comfort and breathing during a severe episode.
AsyutAges 18–80 - NCT05668637Recruiting
AI tool to support care decisions for ventilated adults
This study tests an artificial intelligence (AI) software that helps clinicians make care decisions for people who are on a breathing machine. It may help teams respond faster and more consistently when complex breathing support is needed.
Cleveland, OhioAges 18 years+ - NCT05602662Recruiting
Music to help sedate adults on a breathing machine
This trial looks at whether listening to music can help make “pharmacological sedation” (medicine to help you relax/sleep) easier or more comfortable for adults in the ICU who are on a ventilator (breathing machine). It may help improve comfort during critical care treatment.
Karlstad, Värmland CountyAges 18–100 - NCT05534243Recruiting
A breathing and brain-signal study for adults on ventilators
This study looks at brain activity during care for adults who are on a breathing machine through a tube in the windpipe. It may help doctors understand how to monitor recovery and guide care after intubation.
Iowa City, IowaAges 18 years+ - NCT05506904Recruiting
Help deciding when to remove a breathing tube
This trial studies a decision-support tool that helps ICU teams decide when it’s safe to try removing (extubating) a breathing tube. It may help reduce delays or avoidable re-intubation by guiding the timing of a low-support breathing trial (SBT).
Edmonton, AlbertaAges 18 years+ - NCT05462600Enrolling by invitation
Breathing monitoring test in non-smokers
This study measures how you breathe and how well oxygen and carbon dioxide move in and out of your lungs. It’s mainly a monitoring study to help researchers understand breathing patterns during a breathing test.
La Jolla, CaliforniaAges 18 years+ - NCT05379673Recruiting
Breathing changes with extra oxygen after surgery
This study looks at whether giving extra oxygen during recovery from general anesthesia changes how you breathe after surgery. You may be offered different oxygen levels around the time you wake up to see what helps your breathing most comfortably.
Stanford, CaliforniaAges 18–70 - NCT05347563Recruiting
Using a chest sensor to improve ventilation in sick children
This trial tests whether a special chest sensor (called electrical impedance tomography, or EIT) can help doctors distribute breathing support more effectively in children with sudden breathing failure. It may help optimize ventilation while the child is being monitored in intensive care or during anesthesia.
Bron, RhoneAges birth–18 years - NCT05350332Recruiting
Testing how lung air volume affects airway narrowing during sleep testing
This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).
Atlanta, GeorgiaAges 18 years+ - NCT05298982Enrolling by invitation
Join a long-term follow-up study for ICU care
This study follows people who joined the TEAM Phase III trial to learn how ICU care affects health over the long term. Your participation helps researchers understand outcomes long after the initial treatment.
Camperdown, New South WalesAges 18 years+ - NCT04530760Recruiting
Study of breathing problems in people with liver scarring on a ventilator
This study looks at whether people with cirrhosis who are on a breathing machine have increased pressure in the belly and small unnoticed breathing mist (microaspiration). It may help doctors better monitor and prevent breathing complications while patients are being mechanically ventilated.
LilleAges 18–99 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05224323Recruiting
Testing a lung opening breathing pattern in early ARDS
This study looks at a specific breathing event (“avalanche phenomenon”) when the lungs are opened in people with early, moderate-to-severe ARDS. The goal is to understand what’s happening in the lungs and whether it can guide better care.
PoitiersAges 18 years+ - NCT05226247Recruiting
Check whether careful weaning prevents lung fluid buildup
This study looks at people on a breathing machine for more than 48 hours who are starting a “spontaneous breathing trial,” a test used to see if they can breathe on their own. It focuses on those at higher risk of “weaning-induced pulmonary edema,” meaning fluid can collect in the lungs during the weaning process.
DijonAges 18 years+ - NCT05160987Recruiting
Sedation choice for ICU patients on breathing machines
This study compares two sedation medicines—remimazolam vs midazolam—for very sick ICU patients who are on a breathing machine. It looks at whether one sedative works better or is safer for keeping patients comfortable while they’re critically ill.
Guangzhou, GuangdongAges 18–80 - NCT05069441Recruiting
Predicting breathing trouble after removing a breathing tube
This study looks at patients who are ready to have their breathing tube removed and checks how to predict who might struggle after extubation. It’s observational, meaning your care won’t be changed—researchers are gathering information to improve future predictions.
ChongqingAges 18 years+ - NCT04987840Enrolling by invitation
Hospital program to reduce unnecessary lung culture tests in kids
This trial studies a hospital quality-improvement program that aims to use fewer “respiratory culture” tests in pediatric intensive care units (PICUs). It may help reduce unnecessary testing while maintaining good care for critically ill children.
Baltimore, MarylandAges Any age - NCT04524585Recruiting
Tested a muscle-relaxing treatment for severe low-oxygen breathing
This study tests whether partially relaxing the breathing-related muscles can help people with severe low oxygen while they are on a breathing machine. It may improve how well the lungs work by changing the way the muscles affect breathing.
Toronto, OntarioAges 18 years+ - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT04494074Recruiting
Cooling fever in ventilated people with septic shock
This study tests whether external cooling can safely lower very high fever in people who are on a breathing machine for septic shock. It may help improve outcomes by controlling fever while they are treated for the infection causing their illness.
AmiensAges 18 years+ - NCT04427826RecruitingPhase 1/Phase 2
Morphine to prevent early NIV failure in COPD flare-ups
This trial studies whether morphine can help people with a COPD flare-up avoid “non-invasive ventilation” (breathing support through a mask) failing early. The goal is to reduce how often people need escalation of care soon after starting NIV.
Grenoble, Isère, Auvergne-Rhône-AlpesAges 18 years+ - NCT04471129Recruiting
Noninvasive breathing support after heart surgery to protect heart function
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
RouenAges 18 years+ - NCT03812718Recruiting
Breathing tube vs throat airway during gallbladder surgery
This trial compares two ways of managing your breathing while you are under anesthesia for elective laparoscopic gallbladder removal. It aims to see which option needs less anesthesia and is safer and easier to use for patients like you.
New Delhi, National Capital Territory of DelhiAges 18–65
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Common questions
- Are there clinical trials for ventilation?
- Yes. Clin2 currently lists 506 recruiting ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.