Clinical trials
Invasive Mechanical Ventilation clinical trials
Below are recruiting invasive mechanical ventilation clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07453966Recruiting
Lung vibration therapy for people on breathing machines with lung infection
This study tests a device that delivers gentle vibrations to the lungs to help clear infection in people who are on a breathing machine. It may help improve oxygen levels and recovery.
Wuhan, HubeiAges 18 years+ - NCT07752004Enrolling by invitation
Using a stress ball during breathing support therapy
This trial tests whether squeezing a stress ball can help reduce stress and anxiety in people who are using a breathing mask that supports their breathing (non-invasive ventilation). It might make the experience more comfortable and help you feel calmer during treatment.
IstanbulAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT06240637Recruiting
Telemonitoring for starting home ventilator
This study tests whether using a remote monitoring system (telemonitoring) helps people adjust better to a new home ventilator. It is for people with long-term breathing problems who are starting a ventilator for the first time.
BarcelonaAges 18 years+ - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT07093125Recruiting
Rehabilitation for ICU patients on a breathing machine
This trial is studying rehabilitation practices for people in the ICU who need a breathing machine (ventilator) for at least 48 hours. It aims to improve recovery and care for critically ill patients.
Genova, ItalyAges 16–100 - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT06655805Recruiting
Registry for automated breathing support in adults
This trial collects data from adults in the ICU who need oxygen therapy, non-invasive ventilation, or a breathing tube with a machine. It looks at how automated settings affect care.
Sankt Gallen, Canton of St. GallenAges 18 years+ - NCT06923267Recruiting
Ultrasound to check heart function during breathing trials
This trial tests if using ultrasound to monitor your heart during a breathing test can help predict if you will need the breathing tube again. It is for people on a ventilator for at least 24 hours who are at higher risk of needing the tube reinserted.
OrléansAges 18 years+ - NCT06491017Recruiting
Better airway clearance for ventilated patients
This trial tests if a special machine (mechanical insufflation-exsufflation) can help remove thick mucus from the lungs of patients who are on a breathing tube and ventilator. The goal is to see if optimized settings clear more mucus than standard care.
BarcelonaAges 18 years+ - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT06581939Recruiting
Early rehab with nutrition after ICU ventilation
This study tests whether starting physical therapy and tailored nutrition early and continuing for a longer time helps people recover after being on a breathing machine and blood pressure support in the ICU.
AlbiAges 18 years+ - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT06719258Recruiting
Trial on heated humidifiers for breathing tubes
This trial studies how heating and adding moisture to the air breathed through a breathing tube (called a heated humidifier) affects patients in intensive care. It focuses on people who need the breathing tube for a longer time or special protective settings.
Québec, QuebecAges 18 years+ - NCT06805357Recruiting
Lung opening during chest therapy on a breathing machine
This study tests a method to improve lung function during chest physical therapy for patients on a breathing machine. It may help clear mucus and make breathing easier.
CréteilAges 18–100 - NCT07455214Recruiting
Heart rate variability and breathing trial success in ventilated patients
This study looks at whether heart rate patterns can help predict if a person on a breathing machine is ready to breathe on their own. It may help doctors decide the best time to try removing the breathing tube.
New Taipei CityAges 18–85 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT06053684Recruiting
Comparing two breathing machines for babies with bronchiolitis
This study tests if a new type of breathing machine (NAVA) works better than the standard machine for babies under 2 with severe bronchiolitis in the pediatric ICU. The goal is to see which machine helps babies breathe easier and avoid needing a breathing tube.
The Bronx, New YorkAges birth–2 years - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT06609577Recruiting
Ultrasound-guided diaphragm pacing for patients on ventilators
This trial tests a personalized pacing device that uses ultrasound to help your diaphragm muscle work better while you are on a breathing machine. It may help you breathe on your own sooner and improve your recovery.
Nantong, JiangsuAges 18–95 - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Hershey, PennsylvaniaAges 18 years+
Hear when a new Invasive Mechanical Ventilation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for invasive mechanical ventilation?
- Yes. Clin2 currently lists 131 recruiting invasive mechanical ventilation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a invasive mechanical ventilation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a invasive mechanical ventilation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.