Clinical trials
Whole Genome Sequencing clinical trials
Below are recruiting whole genome sequencing clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05661305Recruiting
Egyptian healthy adults for heart and MRI study
This trial studies how healthy hearts work in Egyptian adults who do not have known heart problems. It may help researchers understand heart health and risk factors, using an MRI scan.
AswānAges 18 years+ - NCT02077894Recruiting
Genetic testing to help identify inherited eye conditions
This study uses whole exome and whole genome genetic tests to look for DNA changes linked to inherited or congenital eye problems. It may help families and doctors better understand the cause of the eye condition and guide future care.
Bethesda, MarylandAges 1 day–120 years - NCT07718971Enrolling by invitation
Whole-genome sequencing for unexplained medical conditions
This study uses whole-genome sequencing (a complete read of your DNA) to try to find a genetic cause for unexplained medical conditions. If you have a puzzling illness without a clear diagnosis, this test might give you answers.
Seattle, WashingtonAges 18–50 - NCT07703670Recruiting
MicroRNA markers in first episode schizophrenia
This study looks at tiny molecules called microRNAs in the blood of people having their first episode of schizophrenia. It aims to find markers that could help guide treatment choices.
Glen Oaks, New YorkAges 15–40 - NCT04528303Recruiting
Genetic testing comparison for long-lasting childhood diarrhea
This study compares two types of genetic tests—whole genome sequencing and whole exome sequencing—to find causes of long-lasting diarrhea in children. It may help doctors diagnose the reason for diarrhea faster, which can guide treatment.
Shanghai, Shanghai MunicipalityAges Up to 6 years - NCT04770519Recruiting
Family genetic study for eye misalignment and nystagmus
This study looks at genetics in families where eye misalignment (strabismus) and/or constant eye shaking (nystagmus) runs. It may help researchers understand the causes and guide future testing or treatments.
Boston, MassachusettsAges Any age - NCT04903782Recruiting
Family whole-genome testing for children with newly diagnosed cancer
This study offers whole-genome testing (a way to read a person’s DNA) to families after a child is newly diagnosed with cancer. It aims to find inherited changes that may explain why cancer happened and guide future care or monitoring.
Newcastle, New South WalesAges Up to 21 years - NCT04986657Recruiting
Whole genome testing to help diagnose AML or MDS
This study checks whether adding whole genome sequencing (reading a person’s DNA more broadly) alongside standard genetic tests improves the diagnosis process for AML or MDS. It may help doctors decide on the best next steps when AML/MDS is suspected.
St Louis, MissouriAges 18 years+ - NCT05306600Recruiting
Study genes in breast and prostate cancers in Brazil
This study looks at tumor tissue and blood to map genetic features of breast and prostate cancers in Brazil. It helps understand cancer patterns in the public health system and may guide future testing and treatments.
Manaus, AmazonasAges 18 years+ - NCT05434598Recruiting
Whole-genome testing added to standard testing for MDS
This study checks whether adding whole-genome sequencing (a deeper look at DNA) alongside standard genomic tests helps in evaluating myelodysplastic syndrome (MDS). It aims to see if this extra testing is useful and acceptable during routine care—especially for people newly being worked up for MDS.
St Louis, MissouriAges 18 years+ - NCT05916755Recruiting
Testing tumor clues that predict response to immunotherapy
This study looks for “biomarkers,” or tumor clues, that may help predict who benefits from checkpoint inhibitor immunotherapy in triple-negative breast cancer. It may help doctors choose the right treatment approach in the future, especially when chemotherapy is planned.
BarcelonaAges 18 years+ - NCT06535542Recruiting
Gene testing and digital twins for high cholesterol in Emiratis
This study uses whole genome sequencing and digital twin technology to better understand and manage very high cholesterol in Emirati adults. It aims to identify genetic causes and personalize treatment.
Abu Dhabi, Abu Dhabi EmirateAges 18–55 - NCT06803784Recruiting
Bioproducts in body fluids for early brain disease detection
This study is looking for proteins in blood and other body fluids that could help detect brain diseases like Parkinson's, Alzheimer's, and ALS early. It aims to improve diagnosis and future treatments.
Pozzilli, ItalyAges 20 years+ - NCT06851377Recruiting
Precision genome study for undiagnosed genetic conditions
This study uses a new, high-resolution genome mapping technique to find genetic causes that standard tests might miss. It may help you if you have symptoms of a known genetic syndrome but standard testing came back negative or unclear.
Bosisio Parini, LeccoAges 2 years+ - NCT06999096Recruiting
Long-read gene testing for inherited movement disorders
This study uses a new DNA reading method to find hidden genetic causes of dystonia. It is for people with dystonia who had standard genetic testing that did not find a cause.
MontpellierAges Any age - NCT06762678Recruiting
Studying genes in neurodevelopmental disorders with birth defects
This study is for children or adults with neurodevelopmental conditions and unusual physical features, where standard genetic tests haven't found a cause. Researchers will use RNA and DNA sequencing to look for hidden genetic explanations, which could guide better care.
AngersAges Any age - NCT03385876Enrolling by invitation
Rapid whole genome sequencing for children with suspected genetic illness
This study quickly reads a child’s DNA using whole genome sequencing to look for genetic causes of symptoms. It may help families and doctors better understand an underlying genetic condition and guide medical care.
San Diego, CaliforniaAges Any age - NCT06576713Recruiting
Genome and RNA sequencing for genetic diagnosis of early Parkinsonism
This study uses advanced genetic testing (genome and RNA sequencing) to find the genetic causes of Parkinsonism that starts before age 40 or runs in families. If you join, you will provide a blood sample and a small skin biopsy to help researchers understand your condition better.
Strasbourg, Grand EstAges 18 years+ - NCT05504772Recruiting
Personalized genetic testing for children with cancer
This trial studies how personalized (tailored) genetic testing can help guide care for children with cancer. It may help match treatment choices to each child’s genetic risk, and it includes optional return of germline (inherited) test results.
AdelaideAges birth–25 years - NCT06821386Recruiting
Genetic testing for seriously ill infants in intensive care
This study offers genetic testing for infants under 18 months who are in intensive care with certain health problems that may be genetic. The goal is to find a genetic cause quickly, which could guide care and treatment.
TaipeiAges Up to 1.5 years - NCT06948344Recruiting
Genetics study for inherited heart muscle disease
This study is looking for people with inherited heart muscle disease that may be genetic. It uses advanced genetic testing to better understand the cause.
SeoulAges 19 years+ - NCT06244940Recruiting
Genetic testing study for heart defects in pregnancy
This study tests a new way to find genetic causes of congenital heart disease (a heart problem found before birth) using samples from amniocentesis or chorionic villus sampling. It may help parents get a clearer diagnosis and plan for their baby's care.
San Diego, CaliforniaAges 18 years+ - NCT06541080Recruiting
CollectNET 2.0: Blood Sample Collection for Neuroendocrine Tumors
This study collects blood samples from people with neuroendocrine tumors (NENs) to build a sample bank for future research. It looks at how tumors change over time and how they respond to treatment.
Rumst, AntwerpAges 18 years+ - NCT06289270Recruiting
Bladder cancer and urine bacteria study
This study looks at bacteria in urine and the bladder to understand if they play a role in causing bladder cancer. Researchers will compare samples from men with bladder cancer and healthy controls.
Cairo, Giza GovernorateAges 18 years+
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Common questions
- Are there clinical trials for whole genome sequencing?
- Yes. Clin2 currently lists 54 recruiting whole genome sequencing studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a whole genome sequencing trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a whole genome sequencing trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.