Treatment
Capsaicin clinical trials
We’re tracking 19 recruiting studies that include Capsaicin, each written for real people, not researchers, below.
Recruiting studies
- NCT06023706RecruitingPhase 3
Capsaicin patch for tailbone pain
This trial tests a capsaicin 8% patch — a pain-relieving skin patch — to see if it can reduce tailbone pain that has lasted more than 3 months. You may be eligible if you have tried other treatments without success and have nerve-related pain symptoms.
BrestAges 18 years+ - NCT06444919RecruitingPhase 4
Capsaicin patch for finger osteoarthritis with nerve pain
This study tests if a capsaicin patch (a hot pepper extract) can reduce finger pain in people with osteoarthritis who also have nerve-like pain. It's for those who haven't gotten enough relief from standard painkillers.
Clermont-FerrandAges 18 years+ - NCT03511846Enrolling by invitationPhase 1
Pain biomarker study for headache or back nerve pain
This study looks at measurable “pain signals” (biomarkers) in people with certain headache disorders or lumbar nerve pain, and compares them with healthy people. It may help researchers better understand what drives pain and how it can be detected.
Houston, TexasAges 18 years+ - NCT07602387Recruiting
Capsaicin cream for chemo-related nerve pain in legs
This study tests whether an 8% capsaicin cream (a chili-pepper derived treatment) can help reduce nerve pain and numbness in the legs caused by cancer chemotherapy drugs (taxanes). The cream is applied directly to affected areas, and the research team will track whether it improves your symptoms and pain levels over time.
Boulogne-Billancourt, HAUTS DE SEINEAges 18 years+ - NCT05840562RecruitingPhase 3
Capsaicin skin patch vs duloxetine for nerve pain after chemo
This Phase 3 trial tests whether a capsaicin patch works better than duloxetine tablets to reduce painful nerve pain after chemotherapy. It aims to help people whose “gloves and socks” nerve pain has lasted after chemo.
AngersAges 18 years+ - NCT05983263Recruiting
Testing capsaicin patch for tailbone pain
This study looks at how well a capsaicin 8% patch (QUTENZA®) works for pain in the tailbone area (coccygodygnia). It reviews past medical records of people who already received this treatment.
NantesAges Any age - NCT05997979RecruitingPhase 3
Capsaicin patch for nerve pain in children after surgery or injury
This trial tests whether a capsaicin 8% skin patch can safely reduce nerve pain in children ages 12 to 17 who have had pain for more than 3 months after surgery or an injury. The patch is applied to the painful area and may offer relief without daily pills.
AmiensAges 12–17 - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT07406971RecruitingPhase 2
Capsaicin nose spray for acute stroke
This trial tests a capsaicin spray applied inside the nose to stimulate a nerve cluster behind the nose, which may help improve blood flow in people having a moderate to severe stroke within the last 24 hours.
Aguascalientes, AguascalientesAges 18 years+ - NCT06540456Enrolling by invitation
Capsaicin patch for nerve-related lower back pain
This study tests a medicated patch called Qutenza (capsaicin) to treat chronic lower back pain that involves nerve damage. The patch is placed on the skin to help reduce pain signals.
Summerville, South CarolinaAges 18 years+ - NCT06744816RecruitingEarly Phase 1
Can capsaicin cream ease nerve pain after chemotherapy?
This study tests whether a capsaicin cream (made from chili peppers) can help reduce pain in the legs caused by nerve damage from past chemotherapy. It's for people who still have pain 3 months or more after finishing chemo.
Houston, TexasAges 18 years+ - NCT07717918RecruitingPhase 1
Testing a new eye drop for capsaicin-induced eye pain
This trial tests whether a new eye drop, BL1332, can reduce eye pain caused by capsaicin (the compound that makes chili peppers spicy). If you are a healthy adult and have no eye problems, this study could help see if the drop is safe and works.
Newport Beach, CaliforniaAges 18–65 - NCT05817591Recruiting
Testing how high-dose capsaicin affects nerve pain
This study looks at what “response profiles” different people have after treatment with high-concentration capsaicin for nerve-related pain. It may help doctors predict who benefits from capsaicin by measuring changes in symptoms and nerve sensitivity.
AnnecyAges 18 years+ - NCT04415892Recruiting
Studying a therapy target for nerve pain after chemotherapy
This study looks at “TRP channels,” which are part of how nerves sense pain and temperature, to understand nerve pain (neuropathy) after chemotherapy. It may help improve how future treatments prevent or reduce nerve pain in people who have had certain chemotherapy drugs.
Leuven, Vlaams-BrabantAges 18–75 - NCT06363305Recruiting
How capsaicin affects heart health in men and women
This study tests whether the compound that makes chili peppers spicy (capsaicin) affects heart health differently in men and women. If you have high blood pressure but are otherwise healthy, you may be able to join.
Saratoga Springs, New YorkAges 18 years+ - NCT06807164RecruitingPhase 2
Comparing three injections for nerve pain after breast cancer surgery
This trial tests three different injections (a nerve block, capsaicin, or botox) to find which works best for chronic nerve pain after breast cancer surgery. If you have ongoing pain in a small area on your chest, armpit, or arm that started 3 to 9 months after surgery, this study may help you find better relief.
Lille, Hauts-de-FranceAges 18 years+ - NCT07054840Recruiting
Pain and walking learning in older adults
This study looks at how pain affects learning to walk on a special treadmill that moves each leg at a different speed. It's for healthy older adults who want to understand how pain might change the way they learn new walking patterns.
Newark, DelawareAges 55–90 - NCT07122973Recruiting
Mapping itch and pain receptors on the skin
This study looks at how the skin senses itch and pain by applying a small amount of chili cream (capsaicin) to different spots. It may help doctors better understand pain and itch conditions in the future.
Gistrup, AalborgAges 18–60 - NCT07237022Recruiting
How TRP channels affect diabetic nerve pain
This study looks at how certain channels in your body (TRP channels) might be involved in diabetic peripheral neuropathy (nerve pain from diabetes), using tests on the skin. It may help find new ways to treat nerve pain.
LeuvenAges 18–45
What Capsaicin is being studied for
Conditions with recruiting Capsaicin studies.
Common questions
- Are there clinical trials studying Capsaicin?
- Yes. Clin2 currently lists 19 recruiting studies that include Capsaicin, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Capsaicin trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Capsaicin an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Capsaicin or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.