Treatment
Comparator clinical trials
We’re tracking 1,749 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT06754644RecruitingPhase 3
Study of QL2107 plus chemo vs. Keytruda for advanced lung cancer
This trial tests a new drug, QL2107, combined with chemotherapy, compared to the standard drug Keytruda (pembrolizumab) with chemotherapy. It is for people with stage IV non-squamous non-small cell lung cancer that does not have certain gene mutations (EGFR or ALK).
Jinan, ShandongAges 18–75 - NCT06844357RecruitingPhase 2/Phase 3
New embolization vs standard for liver cancer
This trial tests a new embolization treatment (TATE) against standard therapy for people with intermediate-stage liver cancer that hasn't spread. The goal is to see if TATE works better at controlling the tumor.
Nanjing, JiangsuAges 18 years+ - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT06822426RecruitingPhase 3
Preventing infections in central lines for people on IV nutrition
This trial tests a new catheter lock solution (DefenCath) to prevent infections in people who need long-term IV nutrition through a central line. It compares the study drug to a standard heparin lock, and you'll be randomly assigned to one group.
Los Angeles, CaliforniaAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06734351RecruitingPhase 3
Comparing two gels for cheek fullness
This study tests a new injectable gel (NOA VOLUME) for restoring fullness in the cheeks, comparing it to an already-approved gel (JUVÉDERM VOLUMA XC). It's for adults with moderate to severe cheek hollowing who want a safe, effective option.
Birmingham, AlabamaAges 22 years+ - NCT07628400Recruiting
Exercise comparison for postpartum abdominal separation
This study compares two types of gentle exercises to help close the gap that forms between abdominal muscles after childbirth. You'll be assigned to one exercise program and measured to see which works better.
Sukkur, Punjab ProvinceAges 24–40 - NCT07628413Recruiting
Exercise Methods for Neck and Shoulder Pain
This study compares two types of gentle exercise programs—Egoscue and Feldenkrais—to help people with chronic neck pain and poor posture. Both programs focus on retraining muscles and improving how your body moves, and the study will measure which approach works better.
Lahore, Punjab ProvinceAges 25–45 - NCT07280858RecruitingPhase 1/Phase 2
Testing a new sarbecovirus vaccine in healthy adults
This study tests a new vaccine called GBP511, designed to protect against several types of sarbecoviruses (including COVID-19). It is for healthy adults who have already received a primary COVID-19 vaccine series plus at least one booster, at least 24 weeks before joining.
Sydney, Kent StreetAges 18 years+ - NCT07646184Enrolling by invitation
Nerve Block Techniques for Upper Back Surgery Pain
This trial compares two types of numbing injections (nerve blocks) used during upper back spine surgery to see which one works better for pain relief. Both techniques are already used in surgery; this study tests which may be more effective.
Tanta, State/Province:*Ages 18–60 - NCT04944615Recruiting
IVUS-guided stent placement for blocked heart artery using longer guidance
This trial compares two ways to place a stent (a small mesh tube) for a completely blocked heart artery: using an IVUS camera inside the artery versus using a standard x-ray approach. It may help people get better heart outcomes by improving how accurately the stent is placed in long-term blockages.
BeijingAges 18 years+ - NCT07506382Recruiting
Comparing two self-expanding aortic valves in TAVR
This study compares two types of self-expanding aortic valves used during a minimally invasive procedure called TAVR. It aims to see which type works better in everyday practice.
Montpellier, OccitanieAges 18 years+ - NCT07263386RecruitingPhase 2
Immunotherapy plus chemo for PD-L1-positive stomach cancer
This trial tests whether adding the immunotherapy drug sintilimab to standard chemotherapy (SOX) after surgery helps prevent stomach cancer from returning. It’s for people whose tumors have a protein called PD-L1 and who had cancer in at least 7 lymph nodes.
Nanjing, JiangsuAges 18–75 - NCT07696702Recruiting
Comparing pulp capping for deep cavities in adult back teeth
This study tests two ways to treat deep cavities that reach the nerve of the tooth, to see which helps the nerve heal better. It may be an option if you have a deep cavity in a lower molar and the nerve is still healthy.
Rohtak, HaryanaAges 18–40 - NCT07633340Recruiting
Shock Wave Therapy Plus Rehab for Shoulder Blade Problems
This study compares two treatment approaches for scapular dyskinesis (abnormal shoulder blade movement): one group receives shock wave therapy along with standard exercises, while the other group does exercises alone. Researchers want to see if adding shock wave therapy helps improve shoulder blade function and reduces pain.
TantaAges 18 years+ - NCT04271488RecruitingPhase 1
Study drug levels in people with mild or moderate liver problems
This Phase 1 study measures how tasurgratinib (E7090) and its breakdown product move through the body in people with mild or moderate liver impairment. It aims to understand appropriate dosing and safety considerations for liver impairment.
Hakata, FukuokaAges 20–79 - NCT07257367Recruiting
Pressure sensing sheath vs. traditional blood pressure monitoring in wrist procedures
This trial compares a new pressure-sensing sheath that monitors blood pressure during wrist-artery procedures to the traditional method. It aims to see if the new device works just as well or better, and is for patients who are already scheduled for a planned (not emergency) procedure needing continuous blood pressure monitoring.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07047729Recruiting
Early vs. standard eating after emergency bowel surgery
This trial compares two different ways of starting to eat after emergency bowel surgery: one group begins eating earlier than usual, and the other follows the standard timing. The goal is to see which approach helps you recover faster with fewer problems.
Lahore, Punjab ProvinceAges 18 years+ - NCT07520487Recruiting
Ketamine Plus Spinal Anesthesia for Older Adults Undergoing Leg Surgery
This study tests whether adding ketamine (a type of anesthetic medication) to spinal anesthesia—numbing medication injected near the spine—can make the numbness last longer for older adults having leg surgery. The goal is to see if this combination improves pain control after surgery.
Cairo, Giza GovernorateAges 65 years+ - NCT07625358Recruiting
How Caffeine and Alcohol Affect Your Eyes
This study measures how caffeine and alcohol change the size of your pupils (the dark circles in your eyes). Researchers want to understand how these common substances affect your eye's natural responses, which could help with vision and neurological research.
SingaporeAges 30–50 - NCT07615868RecruitingPhase 1
New blood-thinner study for heart disease patients in China
This study tests a new medication called selatogrel in people with chronic coronary syndrome (long-term heart disease caused by narrowed heart arteries). Researchers want to see how the body processes this drug and whether it helps prevent future heart problems.
BeijingAges 18–85 - NCT06687369RecruitingPhase 3
Comparing a potential biosimilar to Keytruda for advanced lung cancer
This trial tests if a new drug, MB12, works as well as Keytruda for people with advanced non-small cell lung cancer who haven't had treatment yet. It aims to offer a more affordable option.
YerevanAges 18 years+ - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT06128018Recruiting
Endoscopic vs surgical bypass for stomach blockage
This study compares two ways to help with gastric outlet obstruction (a blockage in the stomach or small intestine) caused by a tumor. It tests if a procedure using an endoscope (a long, flexible tube with a camera) is as good as surgery to help you eat and drink more comfortably.
Orlando, FloridaAges 18 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,749 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.