Treatment
High dose rifampicin clinical trials
We’re tracking 8 recruiting studies that include High dose rifampicin, each written for real people, not researchers, below.
Recruiting studies
- NCT04521803RecruitingPhase 2
Higher-dose rifampicin for TB fluid around the heart
This Phase 2 study compares a higher dose versus the standard dose of rifampicin, a TB antibiotic, for people with TB-related fluid buildup around the heart. It aims to see which dose works better and is safe in improving TB pericarditis with fluid.
Mthatha, Eastern CapeAges 18 years+ - NCT05383742RecruitingPhase 2
Compare 6- vs 9-month treatment for tuberculous meningitis
This Phase 2 study tests whether a shorter, stronger 6-month set of medicines works as well as the usual 9-month regimen for tuberculous meningitis (TB infection in the covering of the brain/spinal cord). The goal is to improve outcomes while reducing treatment time and exposure.
Porto AlegreAges 15 years+ - NCT06057519RecruitingPhase 3
Optimized rifampicin dosing for TB
This trial tests whether higher or standard doses of the antibiotic rifampicin work better for treating pulmonary tuberculosis (a lung infection). You may benefit if you are starting TB treatment and have not had a bad reaction to rifampicin before.
TurinAges 18 years+ - NCT05069688RecruitingPhase 1
Testing dolutegravir dosing in HIV and TB children
This study looks at the right way to dose dolutegravir (an HIV medicine) in young children who also have active tuberculosis (TB). Doctors will measure how the medicine moves through the body, especially when standard vs higher-dose rifampicin is used.
Ibadan, Oyo StateAges 4 weeks–5 years - NCT05012033Recruiting
Study how high-dose steroids move through the body
This study measures blood levels of high-dose steroid medicines (prednisolone or related steroids) to understand how the body processes them in different real-life situations. It may help improve how steroids are dosed and monitored for people needing short-term or longer-term anti-inflammatory treatment.
LondonAges 18–75 - NCT06199921RecruitingPhase 2
Atorvastatin plus TB treatment for new tuberculosis
This study tests whether adding the cholesterol drug atorvastatin to standard TB treatment helps people recover faster. It is for people with newly diagnosed, drug-sensitive tuberculosis who have not yet started treatment.
Zaria, Kaduna StateAges 12–65 - NCT06748937RecruitingPhase 2
Testing alpibectir plus ethionamide for new TB
This study tests an experimental oral TB drug called alpibectir given together with ethionamide for people with newly diagnosed lung TB. The goal is to see how well the combination works and if it is safe.
Cape Town, Western CapeAges 18–65 - NCT06364267RecruitingPhase 2
Low dose exemestane vs low dose tamoxifen for breast cancer prevention
This trial compares two low-dose medications, exemestane and tamoxifen, to see which is better at preventing breast cancer in postmenopausal women who have a higher risk. You would take one of these pills daily for a few years, and the study will check how well it works and what side effects occur.
Genova, ItalyAges Any age
What High dose rifampicin is being studied for
Conditions with recruiting High dose rifampicin studies.
Common questions
- Are there clinical trials studying High dose rifampicin?
- Yes. Clin2 currently lists 8 recruiting studies that include High dose rifampicin, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a High dose rifampicin trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is High dose rifampicin an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether High dose rifampicin or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.