Testing progesterone effects on hormone timing during sleep in teens
Treatments studied
Part of Cancer, Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This early-phase study tests whether a progesterone medicine can change when “luteinizing hormone” (a puberty-related hormone) pulses during wake versus sleep. It focuses on pubertal girls with either normal or higher-than-expected testosterone levels to see how their hormone timing responds.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a mid- to late-pubertal girl with breast development stage 3 or higher, and within 2 years after your first period
- You meet blood-test criteria for either normal or higher-than-expected free testosterone (and/or visible unwanted hair)
- You are healthy enough for study testing, aside from being overweight/obese, having hyperandrogenism, or having properly treated hypothyroidism
- You can provide assent/consent, and a parent/guardian can consent if required for your age
- You agree to avoid pregnancy during the study using reliable non-hormone birth control methods
- You are able to follow medication limits before and during the study (certain hormone, sugar, cholesterol, blood pressure, steroid, and related medicines must be avoided)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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