Endoxifen for early puberty in girls with McCune-Albright syndrome
Part of Hormones & metabolism clinical trials.
This trial tests a study drug called endoxifen to see if it can help stop early puberty and vaginal bleeding in girls with McCune-Albright syndrome. It might help by blocking the effects of estrogen, the hormone that causes these symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Girls aged 4 to 9 years
- Weigh at least 16 kg (about 35 pounds)
- Diagnosed with McCune-Albright syndrome and have signs of early puberty (like vaginal bleeding before age 8)
- Have had at least 2 episodes of vaginal bleeding in the last 6 months
- Be able to swallow small capsules with water
- Parent or guardian must agree to the study and follow its schedule
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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