Hormone therapy for teens with early menopause
Treatments studied
Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.
This trial tests whether hormone replacement therapy (HRT) helps protect bone health in teenagers with premature ovarian insufficiency (POI). It compares HRT to a placebo and also includes healthy volunteers for comparison.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 11 and 19 years old
- You were assigned female at birth
- You have been diagnosed with premature ovarian insufficiency (early menopause), with a blood test showing high FSH
- You are not pregnant and agree to use birth control if sexually active
- You do not have Turner syndrome or celiac disease, and you are not taking bone-affecting medications
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study follows women with premature ovarian insufficiency (POI) over time to understand how it affects their health. Researchers will collect samples and track health changes to learn more about the condition and its long-term effects.
This study looks at how bone health changes in women with premature ovarian insufficiency (early menopause). It aims to understand the body's bone metabolism to help manage long-term health.
This study measures how quickly the heart “recharges” between beats (often shown as QT timing). It compares women with premature ovarian insufficiency to healthy women to understand whether ovarian insufficiency is linked to heart rhythm differences.
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