Clin2
NCT06851754Possibly a fitRecruiting

Hormone therapy for teens with early menopause

Premature Ovarian Insufficiency

Treatments studied

Part of Hormones & metabolism, Women’s health & pregnancy clinical trials.

This trial tests whether hormone replacement therapy (HRT) helps protect bone health in teenagers with premature ovarian insufficiency (POI). It compares HRT to a placebo and also includes healthy volunteers for comparison.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
185 people
Ages
11 years to 19 years
Study type
Interventional

Who can take part

  • You are between 11 and 19 years old
  • You were assigned female at birth
  • You have been diagnosed with premature ovarian insufficiency (early menopause), with a blood test showing high FSH
  • You are not pregnant and agree to use birth control if sexually active
  • You do not have Turner syndrome or celiac disease, and you are not taking bone-affecting medications

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06067529Recruiting
Study on the health effects of early menopause

This study follows women with premature ovarian insufficiency (POI) over time to understand how it affects their health. Researchers will collect samples and track health changes to learn more about the condition and its long-term effects.

Hangzhou, Zhejiang
NCT04167033Recruiting
Checking heart rhythm timing in women with premature ovarian insufficiency

This study measures how quickly the heart “recharges” between beats (often shown as QT timing). It compares women with premature ovarian insufficiency to healthy women to understand whether ovarian insufficiency is linked to heart rhythm differences.

Bordeaux
NCT06754332Not yet recruiting· Phase 1
HCG injection for early menopause-related infertility

This trial tests whether a hormone injection called HCG can activate dormant egg follicles in women under 40 who have gone through premature ovarian insufficiency (POI). If successful, it may help these women conceive.

NCT07815509Not yet recruiting· Phase 2
Finerenone for early menopause in women under 40

This trial tests a medicine called finerenone to see if it can help women with premature ovarian insufficiency (early menopause). It may help restore ovarian function and improve quality of life.

Shenzhen, Guangdong
NCT07843030Not yet recruiting· Early Phase 1
Herbal formula for premature ovarian insufficiency

This study tests whether a traditional Chinese herbal formula can improve ovarian function in women with premature ovarian insufficiency. The aim is to see if the herbal medicine helps by reducing cell damage and changing how genes are regulated.

Beijing
NCT07587853Not yet recruiting
Genetic causes of early menopause

This study looks at the genes that may cause premature ovarian insufficiency (POI), a condition where the ovaries stop working before age 40. The researchers will compare the genes of women with POI to those with normal ovarian function, which may lead to better understanding and future treatments.

Bornova, İzmir

Hear when a new Premature Ovarian Insufficiency trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.