Clin2
NCT01174121Possibly a fitRecruiting

Immunotherapy made from your tumor-fighting immune cells

Metastatic Colorectal CancerMetastatic Pancreatic CancerMetastatic Ovarian CancerMetastatic Breast CarcinomaMetastatic Endocrine Tumors/ Neuroendocrine Tumors

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.

This trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes, or TILs) for certain metastatic cancers. It’s designed for people whose cancer has not responded to standard treatments and who can safely provide a small tumor sample for cell-making.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
332 people
Ages
18 years to 72 years
Study type
Interventional

Who can take part

  • You have metastatic cancer in an allowed type (GI/upper or lower, liver/bile ducts, genitourinary, breast, ovarian/endometrial, or certain endocrine tumors like neuroendocrine).
  • Your cancer has at least one visible spot that can be removed safely so TILs can be made from the tumor tissue.
  • Your cancer has been treated with standard medicines already and is considered “refractory” (not responding or no longer responding), based on your cancer type.
  • You’re age 18 to 72, and you’re well enough to do daily activities (ECOG 0 or 1).
  • If you have up to 3 small, symptom-free brain metastases (under 1 cm), you may qualify if they’re stable after treatment—or they’ve been removed surgically.
  • Your blood and organ test results are adequate (for example, enough white blood cells, platelets, hemoglobin, and acceptable liver/kidney function), and you can complete consent.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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