Testing heart procedures to fully open blocked coronary arteries
Part of Heart & circulation clinical trials.
This trial compares different ways to treat serious heart artery blockages in people with a recent heart attack or unstable chest pain. It aims to see which revascularization approach works best when doctors think the heart arteries can be fully treated.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 18 or older and be able to sign consent paperwork
- Have a recent heart problem called NSTE-ACS (NSTEMI or unstable angina) without ST-elevation on an ECG
- Be someone whose heart team decides you need an invasive procedure within about 72 hours
- Have significant disease in multiple coronary areas (at least two major arteries), with specific blockage thresholds on angiogram testing
- Be able to get complete revascularization planned on both possible approaches (CABG surgery and PCI stent procedure), as agreed by the Heart Team
- Not have recent stent or bypass surgery, recent stroke/bleeding stroke, kidney failure on dialysis, or be pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new imaging technique called μFR to help doctors decide which blockages in your heart arteries need treatment after you've had a heart attack. It may help identify which blockages are most dangerous and need fixing soon versus those that can wait.
This trial studies whether doing a planned, staged treatment for some artery blockages after a heart attack can improve outcomes. It uses detailed images of the heart arteries and compares results in people who are stable after their initial emergency procedure.
This trial is comparing two common heart procedures—bypass surgery (CABG) and stents (PCI)—to see which works better for women with blockages in multiple heart arteries. It aims to find the best treatment for women, who are often underrepresented in heart research.
This trial studies whether two ways of threading a device to open a long-term blocked coronary artery are both safe and effective. You may qualify if you have a chronic total blockage and heart-related symptoms, and you can follow the study follow-up plan.
This study compares two ways of deciding how completely to open blocked heart arteries using drug-eluting stents. It aims to see which guidance approach improves results and safety for people with coronary artery disease who need a PCI (heart catheter procedure).
This trial compares two ways to treat patients who have had a recent heart attack and have multiple blocked arteries. It tests whether fixing all blockages at once is better than doing it in stages.
Hear when a new Multivessel Coronary Artery Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.