Clinical trials
Multivessel Coronary Artery Disease clinical trials
Below are recruiting multivessel coronary artery disease clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07691502Recruiting
Using CT scans before angioplasty to plan treatment
This trial tests if using a special heart CT scan (CCTA with FFRCT) before a planned angioplasty can help doctors better plan where to place stents. You may be eligible if you have a narrowing in one or two heart arteries that haven't been treated before.
Minneapolis, MinnesotaAges 22 years+ - NCT07324720Recruiting
Comparing ischemia vs plaque risk for high-risk artery disease
This trial compares two ways to decide which heart artery blockages need treatment: one looks at blood flow, the other at plaque buildup and risk. It's for people with high-risk blockages to see which approach leads to better outcomes.
Seoul, Main BuildingAges 19 years+ - NCT07314138Recruiting
Comparing two minimally invasive heart bypass surgeries for three-vessel disease
This trial compares two types of heart bypass surgery for people with blockages in three main heart arteries. It tests a hybrid approach that combines a small incision bypass with a stent, versus a standard off-pump bypass. This may mean less recovery time for some patients.
Leuven, Vlaams BrabantAges 18–85 - NCT06168305Enrolling by invitation
Safety and effectiveness of a GENOSS stent in multiple blocked arteries
This trial tests a new drug-coated stent (GENOSS® DES) for people with blockages in multiple heart arteries. It aims to see how safe and effective the stent is for these patients.
Seoul, SeoulAges 19 years+ - NCT04795193Enrolling by invitation
Minithoracotomy vs open surgery for multiple blocked heart arteries
This trial compares two types of bypass surgery for people with multiple blocked heart arteries, to see which one better improves quality of life and how well the bypasses stay open. You may be assigned based on your preferences, and the study also tracks heart scan and follow-up results.
Beijing, Beijing MunicipalityAges 25–85 - NCT07628270Recruiting
Heart Surgery Outcomes Study Using CT Scans and Blood Tests
This study follows patients who had heart bypass surgery guided by special CT scans and blood flow measurements. Researchers want to understand how well the surgery works and study a blood protein called Lp(a) that may affect heart health.
Milan, MIAges 18 years+ - NCT07133984Recruiting
Heart imaging study for people with heart failure and blocked arteries
This study uses heart MRIs to learn more about people who have heart failure and significant blockages in their coronary arteries. If you are planning to have bypass surgery or a stent, the study may be a fit.
Brooklyn, New YorkAges 18 years+ - NCT07363161Recruiting
Drug-coated balloon vs. stent for high-risk heart disease
This trial compares two treatments for people with complex coronary artery disease who have high-risk conditions or complicated blockages: a drug-coated balloon (DCB) versus a drug-eluting stent (DES). Both are ways to open up narrowed arteries and keep them open without surgery.
HomburgAges 18 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT05532631Recruiting
Compare stent procedure versus bypass surgery for weak heart
This study compares two ways to improve blood flow to the heart—using stents through a catheter or bypass surgery—in people with heart muscle weakness and blockages in more than one coronary artery. It may help identify which approach leads to better outcomes over at least two years.
Créteil, Val De MarneAges 18 years+ - NCT05617599Recruiting
Checks safety of a stent used in complex heart artery disease
This study looks at how safe and effective a specific stent (SUPRAFLEX CRUZ) is when used in real-world care for people with heart artery blockages in more than one artery. Some participants will also be selected if their heart pumping strength is reduced.
Elche, AlicanteAges 18 years+ - NCT05701358Recruiting
Guiding heart stent decisions to fully treat blocked arteries after a heart attack
This trial compares two ways doctors decide which additional blocked heart arteries to treat with stents soon after a heart attack. It may help patients avoid later heart problems by testing a “complete revascularization” strategy planned after the initial culprit artery was treated.
Los Angeles, CaliforniaAges 18 years+ - NCT05770349Recruiting
Heart failure patients having bypass surgery are studied
This study looks at tiny structures inside heart muscle cells (especially “power stations” in the cells) in people with certain types of heart failure who are getting coronary bypass surgery. It may help researchers better understand what changes happen in the heart and how this could guide future care.
TomskAges 18 years+ - NCT05786131Recruiting
Stent treatment: fix all blocked arteries vs culprit only
This trial compares two ways of doing a stent procedure in people who had an NSTEMI heart attack: fixing all significant blockages versus fixing only the “culprit” blockage. It may help find which approach is safer and more effective for preventing complications.
GrazAges 18 years+ - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT06104033Recruiting
Drug-coated balloon for patients with heart artery disease in multiple vessels
This trial tests whether a drug-coated balloon is a good treatment option for people who have blockages in two or more heart arteries. It aims to see if this approach can safely open blocked arteries without a permanent stent.
SeoulAges 19–100 - NCT06279663Recruiting
Comparing bypass surgery vs stenting for high-risk heart attacks
This study compares two common treatments (bypass surgery vs. stenting) for people having a high-risk heart attack that involves blockages in multiple arteries. It aims to find which approach leads to better long-term outcomes.
Novosibirsk, Novosibirsk OblAges 18 years+ - NCT06399692RecruitingPhase 3
Heart treatment study for women with blocked arteries
This trial is comparing two common heart procedures—bypass surgery (CABG) and stents (PCI)—to see which works better for women with blockages in multiple heart arteries. It aims to find the best treatment for women, who are often underrepresented in heart research.
Glendale, CaliforniaAges 18 years+ - NCT06399705RecruitingPhase 3
Comparing bypass surgery vs stenting for minority heart patients
This trial compares two common heart procedures—bypass surgery and stenting—for people with multiple blocked arteries. It focuses on minority groups to find out which treatment works best for them. You will be asked to fill out quality-of-life questionnaires for up to 10 years.
Glendale, CaliforniaAges 18 years+ - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+ - NCT04968808Recruiting
Find best timing for stent procedure in NSTEMI with multiple vessel disease
This trial compares when to do a stent procedure (PCI) in people with NSTEMI who have disease in more than one coronary artery (non-IRA). It may help doctors choose the safest and most effective timing for treatment to improve outcomes.
GwangjuAges 19 years+
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Common questions
- Are there clinical trials for multivessel coronary artery disease?
- Yes. Clin2 currently lists 46 recruiting multivessel coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multivessel coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multivessel coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.