Minocycline plus amiodarone to prevent heart rhythm trouble after surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether adding minocycline to amiodarone (or using amiodarone alone) can prevent atrial fibrillation after heart surgery. If you’re at risk for this irregular heartbeat after surgery, the study may help find a safer or more effective way to lower that risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult age 18 or older and can stay in the study for about 6 weeks
- You are having certain heart surgeries (bypass, valve repair/replacement, or both)
- You can use an iPhone and send heart rhythm recordings (ECGs) using your device
- You do not have atrial fibrillation or flutter right now, and you haven’t had it in the last 6 months
- You are able to take the study medicines: amiodarone and minocycline (no known intolerance to either)
- You do not have major liver or kidney problems, and you are not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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