Vernakalant versus amiodarone for irregular heart rhythm after surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial compares two medicines—vernakalant and amiodarone—to see which works better to treat atrial fibrillation after heart surgery. It may help you (or your relative) stay in a steadier heart rhythm during recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had heart surgery for bypass (CABG) and/or valve repair or replacement (not a mechanical valve).
- You are stable right now, including whether you need medicines that raise blood pressure (vasopressors).
- You have NOT had atrial fibrillation or flutter before.
- You did NOT have prior atrial fibrillation/flutter ablation, and you have no plan for a mechanical valve replacement.
- You also should not have certain heart/medical conditions or recent treatments that affect safety (like amiodarone in the last 6 weeks, or drug/heart electrical test problems).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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