Proton beam radiation for certain esophagus cancers
Part of Cancer, Digestive system clinical trials.
This trial studies whether proton therapy can better treat early-to-mid stage esophagus cancer while aiming to reduce side effects to nearby organs. Proton therapy uses a targeted type of radiation, and participants are also checked to be eligible for curative surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed esophagus cancer (squamous cell or adenocarcinoma) that is in the mid, lower part, or where the esophagus meets the stomach (up to the stomach area by 5 cm).
- Your cancer stage must match allowed groups (T1 with limited/near lymph nodes, or T2–T3 with no or limited to certain lymph node involvement).
- Recent tests must be completed: endoscopy with biopsy, CT scan, PET/CT scan, and an endoscopic ultrasound.
- You must have adequate lung, kidney, blood, and liver test results (the trial uses specific cutoffs on the lab values).
- You must be healthy enough for treatment: age 18+, energy level score 0–2, and a surgical consult confirming curative surgery is possible after proton therapy.
- If you could become pregnant (or if you’re male and sexually active), you must use reliable birth control and be willing to complete required pregnancy testing if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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