Clin2
NCT02512432Worth exploringNot yet recruiting

Corneal ring implants for progressive vision loss

Keratoconus

Part of Eyes & vision clinical trials.

This study tests tiny plastic rings (called Intacs) that are placed in the cornea to help reshape it and improve vision. It is for people with a condition called corneal ectasia, where the cornea thins and bulges, and who are otherwise facing a cornea transplant.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
1,000 people
Ages
21 years and older
Study type
Interventional

Who can take part

  • Be 21 years of age or older
  • Have vision that has been getting worse, and glasses or contacts no longer help enough for daily life
  • Have a clear front part of the eye (cornea) with no scarring or cloudiness
  • Have a cornea thickness of at least 450 microns where the implant goes
  • Have a cornea transplant as the only remaining option to improve vision

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT02138669Recruiting
Prescription cornea insert for keratoconus when vision worsens

This trial tests whether prescription inserts placed in the cornea can improve day-to-day vision for people with keratoconus whose vision is getting worse and who have few options left. You may be able to avoid or delay corneal transplant depending on your cornea shape and thickness.

Dallas, Texas
NCT06451718Recruiting
A new implant for keratoconus to avoid corneal transplant

This trial tests a small metal implant placed in the cornea to treat keratoconus, a condition where the cornea thins and bulges. The goal is to see if the implant can safely improve vision and prevent the need for a corneal transplant.

Roma, Roma
NCT04741230Recruiting
Test implant for severe corneal thinning to avoid transplant

This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.

Wolverhampton, West Midlands
NCT05905978Not yet recruiting
Donor cornea treatment for advanced keratoconus

This trial uses donated corneal tissue that was treated with a special light and riboflavin (collagen cross-linking) to strengthen it before transplant. The goal is to improve vision in people with severe keratoconus, a condition where the cornea bulges into a cone shape and gets very thin.

Guangzhou, Guangdong
NCT05676580Recruiting
Study of risk factors and vision changes in keratoconus

This study looks at what leads to keratoconus and how it progresses over time. It may help doctors better predict worsening vision and plan earlier care.

Montpellier, Occitanie
NCT04094090Recruiting· Phase 2
Corneal strengthening treatment for thinning eye shape

This Phase 2 study tests how safe and well a corneal cross-linking device (called PXL-Platinum 330) works for people with corneal ectasia (a thinning/steepening of the cornea). If you qualify, the goal is to help stop or slow further worsening of your cornea shape and improve eye stability.

San Francisco, California

Hear when a new Keratoconus trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.