Transplant trial for severe aplastic anemia with related donor
Treatments studied
Part of Blood & lymphatic clinical trials.
This Phase 2 study tests a bone marrow transplant from a closely matched related donor, plus medicine after the transplant to help prevent immune complications. It may be an option if you have severe aplastic anemia and meet specific health and lab requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aplastic anemia with low blood counts (meeting specific lab cutoffs)
- You have a related donor matched at HLA-A, B, and DR (about 3/6 to 5/6 match) with a negative cross-match
- Your age is 65 or younger if previously treated, or 75 or younger if previously treated
- Your overall performance status is good enough (KPS 70% or higher)
- You have acceptable heart, lung, liver, and kidney function based on set thresholds
- You have not had a prior bone marrow transplant from another person
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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