Study of immune changes in very early childhood type 1 diabetes
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This study looks at immune system cells and gene activity in infants and young children to understand what causes type 1 diabetes to start so early. It may help researchers find earlier warning signs and better ways to support families right at diagnosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- If you have diabetes: it must have been diagnosed within the last 24 months (and meet diabetes test standards).
- You must be under 24 months for the main infant part of the study (or under 70 for another part with different groups).
- You likely must have type 1 diabetes risk based on genetics, or a confirmed single-gene (monogenic) cause.
- If diagnosed under 12 months: you must test negative for non-autoimmune “neonatal diabetes” gene changes (unless this study’s control group matches otherwise).
- You must be well at the time of blood/immune sampling (no significant current illness).
- For the control groups: the participant age and diagnosis status must match the study (and they should not have autoimmune disease or immune system disorders).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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