Hydrocortisone for children with septic shock in the ICU
Treatments studied
Part of Infections clinical trials.
This Phase 3 trial tests whether giving stress-dose hydrocortisone can improve outcomes for children with septic shock in the pediatric intensive care unit (PICU). It is designed for children who are already receiving strong medicines to support blood pressure because of a serious infection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 1 month (corrected age) and under 17 years old, for ICU treatment
- Have a suspected or confirmed serious infection when admitted to the PICU, or when septic shock starts
- Have had infection testing done (like blood/urine/spinal fluid/wound tests) and antibiotics started
- Within the last 24 hours, have abnormal temperature and/or abnormal white blood cell counts, as defined by the study site
- Be on strong blood-pressure support medicines through a continuous IV infusion (vasoactive/inotropic medicines)
- Either be on two or more of these blood-pressure medicines, or on epinephrine or norepinephrine at a specific dose for more than 1 hour
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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