Vitamin C with chemotherapy for lymphoma and blood disorders
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests whether adding high-dose vitamin C (ascorbic acid) to standard chemotherapy helps treat lymphomas that have come back or not responded, as well as two related blood disorders (CCUS and CMML). The goal is to see if the vitamin C makes the chemo work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have lymphoma, a blood condition called CCUS, or a blood cancer called CMML that has either come back after treatment or hasn't responded.
- You must have at least one tumor that can be measured on a scan (at least 1.5 cm across).
- Your overall health must be reasonably good, as measured by standard scoring (ECOG 0–2).
- Your blood counts (hemoglobin, white blood cells, platelets) and liver/kidney function must be within certain limits.
- You must be willing to have a central line (a special IV tube) and to give blood and tissue samples for research.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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