Check how your pacemaker changes heart pumping
Part of Brain & nervous system clinical trials.
This study measures how well the heart pumps at different heart rates in people with pacemakers or defibrillators. It may help doctors understand how pacing settings affect heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old (including both ages)
- You have a permanent implanted pacemaker or implanted defibrillator that can pace the upper and lower heart
- Your heart’s pumping strength is above 50% on an echocardiogram (left ventricular ejection fraction)
- You can and are willing to give informed consent
- You do not currently need a cardiac resynchronization device
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether a special pacing pattern can strengthen your heart's pumping ability. You may qualify if you have heart failure with a low ejection fraction and already have a pacemaker or defibrillator with an atrial lead.
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This study compares two pacemaker pacing strategies—left-sided “bundle branch area” pacing versus right-sided ventricular pacing. It aims to see which approach better prevents heart failure getting worse and reduces abnormal timing between heart chambers over time.
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