Tranexamic acid to reduce knee inflammation after ACL injury
Treatments studied
Part of Bones, joints & muscles, Injuries & trauma clinical trials.
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 30 years old
- Your ACL injury happened within the last 4 days
- Your injured knee has swelling from blood/fluid (effusion or hemarthrosis)
- You do not have an inflammatory arthritis, gout, or pseudogout
- You have not had knee surgery before, and you did not have a prior injury that required crutches
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether tranexamic acid (a medicine that helps blood clot) can reduce blood loss during long spine surgery after an injury. It may help lower the chance of needing transfusions and manage surgical bleeding.
This study tests whether a medication called tranexamic acid can reduce swelling and pain after ACL reconstruction surgery. If you're having this knee surgery, it might help you recover more comfortably.
This study tests whether putting tranexamic acid (a medicine that helps blood clot) directly into the bone during knee replacement surgery can reduce blood loss. It may help people recover with less need for blood transfusions.
This study tests whether giving tranexamic acid during knee surgery reduces bleeding and improves recovery. It is for people having a specific knee realignment procedure called a high tibial osteotomy.
This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.
This study tests whether taking tranexamic acid for up to seven days after knee replacement surgery can reduce swelling, pain, and the need for pain pills. It may help you recover more comfortably after your operation.
Hear when a new Anterior Cruciate Ligament Reconstruction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.