Clinical trials
Anterior Cruciate Ligament Reconstruction clinical trials
Below are recruiting anterior cruciate ligament reconstruction clinical trials, each written for real people, not researchers. We’re tracking 127 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03365908Enrolling by invitation
Pain Management After ACL Reconstruction Surgery
This study looks at ways to manage pain in adults who are getting surgery to repair a torn ACL (a knee ligament). It may help improve comfort and recovery after ACL reconstruction.
Sacramento, CaliforniaAges 18–45 - NCT05527171Recruiting
Virtual reality mindfulness after ACL knee surgery
This study uses a virtual-reality mindfulness meditation program to help improve fear and movement quality after ACL reconstruction. It may help you feel less afraid of movement and land more safely when you return to sports.
Chapel Hill, North CarolinaAges 14–25 - NCT07765173Recruiting
Muscle function after ACL reconstruction in active people
This study looks at how well your thigh muscles work after ACL reconstruction surgery. It aims to understand muscle power recovery in active people, which could help improve rehabilitation programs.
Challes-les-EauxAges 18–65 - NCT06910150Enrolling by invitation
Pain relief after knee surgery: electric stimulation study
This trial tests two types of mild electric stimulation (one with tiny needles, one without) applied to the thigh muscle to reduce pain in people who had ACL knee surgery in the last six weeks. The goal is to see if this can help you feel better and recover quicker.
Madrid, MadridAges 18–55 - NCT06464705Recruiting
PEMF Therapy for Hamstring Strength After ACL Surgery
This study tests whether wearing a special device (PEMF) for a few minutes each day can help you regain hamstring strength more quickly after ACL surgery. If your hamstring is still weaker than your other leg at 4 months, this may help you recover better.
ShatinAges 18 years+ - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT07580157Enrolling by invitation
Shockwave therapy for knee pain after ACL surgery
This study tests whether focused shockwave treatment can reduce knee pain in people who have had ACL (anterior cruciate ligament) reconstruction surgery. Shockwave therapy uses sound waves to reduce pain and inflammation.
Rochester, MinnesotaAges 18 years+ - NCT06493851Recruiting
Hyperbaric oxygen therapy to speed recovery after ACL reconstruction
This trial tests whether hyperbaric oxygen therapy (breathing oxygen in a pressurized chamber) can help you recover faster after ACL knee surgery. If you're having ACL reconstruction, this treatment might reduce healing time.
ZrifinAges 18–45 - NCT06858293Recruiting
Imagining exercises to boost knee strength after ACL surgery
This study tests whether imagining yourself doing exercises can help you regain strength in your thigh muscle after ACL surgery, and if it's something people can stick with during physical therapy.
Milwaukee, WisconsinAges 18 years+ - NCT06538792Recruiting
Proprioception and strength after ACL reconstruction
This study looks at how well people regain body awareness, muscle strength, and fear of movement after ACL knee surgery. It may help understand recovery patterns in the first year after surgery.
IstanbulAges 18–35 - NCT06259968Recruiting
Electrical stimulation after ACL surgery recovery trial
This trial tests if adding electrical stimulation to standard physical therapy helps people recover strength and movement after ACL reconstruction surgery. It compares two rehab programs starting within days after surgery.
Veranópolis, Rio Grande do SulAges 18–40 - NCT06240780Enrolling by invitation
Incrediwear recovery study for ACL and MCL surgery
This trial tests whether wearing Incrediwear clothing helps you recover faster after arthroscopic knee surgery for ACL or MCL tears. It is designed for people about to have surgery and who want to improve their healing process.
Oklahoma City, OklahomaAges 18–65 - NCT05968729Recruiting
Study testing walking changes after ACL surgery
This study looks at how your walking pattern adapts when you follow a purposely uneven walking setup. It may help researchers understand recovery after ACL surgery and how to improve return-to-sport safety.
Storrs, ConnecticutAges 18–30 - NCT05972876Recruiting
Blood-flow restriction rehab after ACL surgery
This trial looks at how well your ACL graft (the repaired tissue) heals after ACL reconstruction when you use a specific rehab method called blood-flow restriction training. It may help your care team understand whether this rehab approach leads to better healing and function.
Sittard, LimburgAges 18–65 - NCT05395767Recruiting
Living-donor tendon graft for ACL repair in teens
This study tests whether an ACL reconstruction using a tendon from a living donor works well and is safe in children and teens. It may help families compare this approach while closely tracking knee function after surgery.
Pembury, KentAges 8–17 - NCT05012982Recruiting
Blood-flow restriction training after ACL surgery
This study looks at whether a special exercise method called blood-flow restriction (BFR) training changes blood and metabolism-related responses after ACL reconstruction surgery. It may help people understand who could safely benefit from BFR during recovery.
Milford, ConnecticutAges 18–60 - NCT04462458Recruiting
Study tracking outcomes after ACL reconstruction surgery
This is a study that follows adults who had an ACL tear treated with ACL reconstruction. It helps understand how the surgical device/material performs in real-world care.
InnsbruckAges 18 years+ - NCT03552705RecruitingPhase 2
Tranexamic acid to reduce knee inflammation after ACL injury
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
Stanford, CaliforniaAges 18–30 - NCT06099600Recruiting
ACL reconstruction study with follow-up via app
This trial is for people getting ACL (anterior cruciate ligament) surgery. It tests if tracking your recovery through questionnaires on a phone or tablet helps improve outcomes.
LyonAges 18 years+ - NCT06798623RecruitingPhase 1
ACL repair with stem cells from your own knee fat
This trial tests whether adding stem cells from your knee fat pad to a standard ACL reconstruction helps you heal better. It is for Houston Methodist patients who can do physical therapy there and meet basic health requirements.
Houston, TexasAges 18 years+ - NCT06662955Recruiting
Exercise with sound cues after ACL reconstruction
This study tests if adding sounds (like a metronome beat) to your rehab exercises helps your leg muscles work better after ACL reconstruction. It is for athletes who had their ACL surgery within the past 2 weeks and are ready to start moving.
Salaya, Changwat Nakhon PathomAges 18–35 - NCT06688344Recruiting
Shock wave therapy after ACL surgery
This trial tests if adding focused shock wave therapy to standard rehab can improve recovery after ACL reconstruction using a hamstring graft. It may help reduce pain and speed up healing.
IstanbulAges 18–45 - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT07020312RecruitingPhase 2
Brain training to improve muscle recovery after joint surgery
This trial tests whether brain-computer interface training can help you regain muscle control more effectively after knee or hip surgery. It focuses on four common procedures and uses neurofeedback to optimize muscle activation during recovery.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for anterior cruciate ligament reconstruction?
- Yes. Clin2 currently lists 127 recruiting anterior cruciate ligament reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- Anterior Cruciate Ligament (ACL) Reconstruction
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Tear
- Anterior Cruciate Ligament
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.