Tranexamic acid to reduce inflammation after knee ligament surgery
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests whether a medication called tranexamic acid can reduce swelling and pain after ACL reconstruction surgery. If you're having this knee surgery, it might help you recover more comfortably.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You are having a first-time ACL reconstruction (a surgery to rebuild the knee's main stabilizer).
- Your surgery will be done using spinal anesthesia (numbing from the waist down) plus a numbing block in the leg.
- You are generally healthy (classified as ASA I or II).
- You are not pregnant or breastfeeding, and you don't take blood thinners that can't be safely stopped.
- You have no bleeding disorders, allergy to the study drug, or history of seizures.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests whether tranexamic acid can reduce swelling and protect knee cartilage after an ACL injury. It may help by limiting bleeding-related inflammation in the injured joint soon after injury.
This study tests whether taking tranexamic acid for up to seven days after knee replacement surgery can reduce swelling, pain, and the need for pain pills. It may help you recover more comfortably after your operation.
This study tests whether taking tranexamic acid (a medication that helps blood clot) for a few days after knee replacement surgery can reduce bleeding and the need for blood transfusions. It may help patients recover with fewer complications.
This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.
This study tests whether putting tranexamic acid (a medicine that helps blood clot) directly into the bone during knee replacement surgery can reduce blood loss. It may help people recover with less need for blood transfusions.
This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.
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