Preventing blood clots after severe brain injury
Treatments studied
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This trial tests whether taking an anti–blood clot medicine (dalteparin) and using leg compression can reduce dangerous blood clots after a severe traumatic brain injury. It may help lower the chance of clots forming when people are immobile and at higher risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 years or older
- You have a traumatic brain injury with low brain function (GCS 8 or less) or moderate brain injury (GCS 9–12) with ICU care and certain brain scan findings
- You can start the first study medicine within 3 days of the injury
- There isn’t ongoing bleeding that can’t be controlled
- You don’t have a known allergy to the study blood thinner (dalteparin or similar heparins) or pork products
- You can use a leg compression device (SCD) on at least one leg during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a special blood clotting test called thromboelastography can help assess clotting problems after a head injury. It may help doctors better understand bleeding risk and related complications early after trauma.
This study tests whether an anti-bleeding medicine (given to reduce unwanted clot breakdown) can improve outcomes after a mild head injury in people 50 and older. It is looking for patients who arrive quickly after injury and have certain symptoms like brief loss of consciousness, confusion, or nausea.
This trial tests if baricitinib, an anti-inflammatory drug, can help people with bleeding in the brain from a head injury. It is for adults with moderate to severe traumatic brain injury who are not immediately having surgery.
This study is testing a new blood-based test to help doctors diagnose traumatic brain injury (TBI) and track recovery or complications. If you have had a head injury and a CT scan as part of your care, you may be able to join.
This trial tests whether giving a platelet transfusion to patients with severe traumatic brain injury who are on antiplatelet medication can improve how well their blood clots. You may qualify if you have a serious brain bleed and are taking a medication like aspirin or clopidogrel.
This Phase 2 trial studies whether giving antithrombin can better prevent harmful blood clots (venous thromboembolism) after serious injuries. The goal is to reduce clot risk while you’re in the trauma ICU or step-down unit.
Hear when a new Traumatic Brain Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.