Targeted radiation for brain metastases using staged stereotactic treatment
Part of Brain & nervous system, Cancer clinical trials.
This Phase 1 study tests a form of focused radiation given in stages to shrink larger brain metastases. It may help people whose tumors are in the brain but not suited to whole-brain radiation alone, while also checking safety and how well the treatment can be delivered.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older, and your cancer in the last 5 years must be a solid tumor (not small cell lung cancer).
- You have a brain metastasis that is still there (not removed) and measures 3 to 6 cm, or you had surgery and now need staged stereotactic radiation.
- An MRI with contrast must be done within 30 days (or you qualify based on the surgery plan).
- You can have had whole-brain radiation before, and you may have multiple brain spots as long as one “main” lesion is 3 to 6 cm.
- You must not have leptomeningeal metastases (cancer spread to the fluid layer around the brain), and the main spot must not have already had radiotherapy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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