SRS radiation for small cell lung cancer with brain spread
Part of Brain & nervous system, Cancer, Lungs & breathing clinical trials.
This Phase 2 trial tests a type of focused radiation (stereotactic radiosurgery, or SRS) for people with small cell lung cancer that has spread to the brain. It looks at whether this approach can treat brain metastases when the cancer has limited to a certain number of spots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have small cell lung cancer confirmed by biopsy/pathology
- Your brain MRI (with contrast) shows 1 to 20 brain metastases
- You are age 18 or older and can consent to the study
- You can have an MRI with contrast (you are not unable to safely get the scan)
- If you are able to become pregnant, you must not be pregnant; pregnancy blood test should be negative at enrollment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 study tests a form of focused radiation given in stages to shrink larger brain metastases. It may help people whose tumors are in the brain but not suited to whole-brain radiation alone, while also checking safety and how well the treatment can be delivered.
This Phase 2 trial tests a brain radiation technique that aims to treat up to a few brain metastases while sparing areas important for thinking and memory. It may help people keep cognitive abilities better than with more brain-wide radiation approaches.
This trial compares two types of radiation for people with small cell lung cancer that has spread to the brain (10 or fewer spots). One approach uses focused radiation only on the tumors, the other treats the whole brain while trying to protect memory. The goal is to see which works better with fewer side effects.
This Phase 2 study tests a precise, no-head-frame radiation technique to treat brain metastases. It may help by aiming radiation tightly at the tumors while limiting exposure to nearby healthy brain.
This Phase 1 study tests how to safely give focused radiation (SRS) at different doses to people with brain metastases. It aims to find a dose level that works well while limiting side effects.
This trial tests a new radiation approach for people with small cell lung cancer that has spread to the brain. It combines whole-brain radiation that avoids the memory centers, followed by focused radiation to the tumors, while you also receive standard chemotherapy and immunotherapy.
Hear when a new Lung cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.