Closed-loop deep brain stimulation for Parkinson’s medication side effects
Part of Brain & nervous system clinical trials.
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can understand the study and sign consent
- You have Parkinson’s and a doctor says you are safe to have DBS surgery
- Your Parkinson’s medicine (levodopa) causes troublesome side effects like involuntary movements or “on-off” swings
- Levodopa improves your symptoms by at least 30% when you’re in the “off” state
- You can return for follow-up visits during the study
- You do not have conditions that block DBS, such as unsafe surgical risk or major brain injury besides Parkinson’s
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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